New Data to be Presented at CHEST 2021 Showcase Clinical Performance of Veracyte’s Genomic Diagnostic Tests in Lung Cancer and Interstitial Lung Disease

On October 6, 2021 Veracyte, Inc. (Nasdaq: VCYT) reported that four abstracts highlighting the clinical impact of the company’s genomic diagnostic tests for lung cancer and interstitial lung disease (ILD) will be presented at the American College of Chest Physicians (CHEST) Annual Meeting 2021, being held virtually October 17-20, 2021 (Press release, Veracyte, OCT 6, 2021, View Source [SID1234590870]).

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The abstracts include new data from an expanded clinical validation study which demonstrate the ability of Veracyte’s Percepta Nasal Swab test to determine cancer risk in patients with lung nodules found on CT scans – across lung nodule sizes, lung cancer stages and patients’ prior-cancer status. Veracyte developed the novel noninvasive test to help physicians more accurately, quickly and confidently determine which patients can be safely directed to routine monitoring and which should proceed to further diagnostic work-up and treatment as needed.

"The Percepta Nasal Swab is a key component of Veracyte’s lung cancer portfolio and expands our ability to answer clinical questions across the patient journey in lung cancer," said Marc Stapley, Veracyte’s chief executive officer. "Collectively, the new data that will be presented at this year’s CHEST meeting demonstrate the power of our cutting-edge genomic science and technology to help physicians and patients make better, faster and more confident care decisions in serious lung diseases."

Additional abstracts to be presented at the CHEST meeting provide further evidence that Veracyte’s Percepta and Envisia classifiers deliver valuable genomic information that helps guide patient care in lung cancer and ILDs (including idiopathic pulmonary fibrosis), respectively.

Following are details of the four abstracts:

Date/Time:

Sunday, October 17, 9:15 a.m.-10:20 a.m. CT

Title:

A Nasal Clinical-Genomic Classifier for Assessing Risk of Malignancy in Lung Nodules Demonstrates Accurate Performance Independent of Nodule Size or Cancer Stage

Abstract #:

39959 (oral presentation)

Presenter:

Carla R. Lamb, M.D., Lahey Hospital & Medical Center

Date/Time:

Sunday, October 17, 9:15 a.m.-10:20 a.m. CT

Title:

Impact of Percepta Bronchial Genomic Classifier on Lung Nodule Management at an Academic Medical Center

Abstract #:

39994 (oral presentation)

Presenter:

Harpreet Singh, M.D., Medical College of Wisconsin

Date/Time:

Monday, October 18, 12:15 p.m.-1:20 p.m. CT

Title:

The Impact of the Envisia Genomic Classifier in the Diagnosis and Management of Patients with Interstitial Lung Disease

Abstract #:

40063 (oral presentation)

Presenter:

Joseph Lasky, M.D., Tulane University Medical School

Date/Time:

On-Demand October 17-21

Title:

Role of Next Generation Sequencing with Percepta Brushing in Reclassifying Lung Nodule Risk After Non-Diagnostic Bronchoscopy

Abstract #:

36774 (poster)

Presenter:

Abhijit Raval, M.D., AnMed Health Medical Center

Aadi Bioscience to Present New Preclinical Data on nab-Sirolimus (ABI-009) at AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics

On October 6, 2021 Aadi Bioscience, Inc. ("Aadi") (Nasdaq: AADI), a clinical-stage biopharmaceutical company focusing on precision therapies for genetically-defined cancers with alterations in mTOR pathway genes, reported it will present a poster at the Virtual AACR-NCI-EORTC (Free AACR-NCI-EORTC Whitepaper) International Conference on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR) (Free ASGCT Whitepaper) (Free EORTC-NCI-AACR Whitepaper) to be held this year from October 7th -10th (Press release, Aadi Bioscience, OCT 6, 2021, View Source [SID1234592087]).

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The Company will present preclinical data evaluating nab-sirolimus (ABI-009) in PTEN-deleted and TSC2-deleted cancer models in comparison with other mTOR inhibitors sirolimus and everolimus and evaluating their effects on important downstream targets S6 and 4EBP1.

Learn more about Aadi’s development of therapies that target the genetic drivers of cancers of the mTOR pathway at www.aadibio.com.

Aadi’s presentation at the 2021 AACR (Free AACR Whitepaper)-NCI-EORTC International Conference:

All times noted are U.S. Eastern Time (ET).

Presentation Title: nab-Sirolimus improves mTOR pathway suppression and antitumor activity versus oral mTOR inhibitors in PTEN null bladder cancer (UMUC3) and TSC2 null liver cancer (SNU398) xenografts
Author: Shihe Hou, Ph.D., Aadi Bioscience, Inc.
Session: mTOR/PI3-kinase, P138
Session Date/Time: Thursday, October 7, 9:00 a.m. and on-demand throughout conference

The poster will be posted to the Events and Presentations section of Aadi Bioscience’s website after 9 am ET on October 7th.

Theseus Pharmaceuticals Announces Pricing of Initial Public Offering

On October 6, 2021 Theseus Pharmaceuticals, Inc. ("Theseus"), a biopharmaceutical company focused on improving the lives of cancer patients through the discovery, development and commercialization of transformative targeted therapies, reported the pricing of its initial public offering of 10,000,200 shares of its common stock at a price to the public of $16.00 per share (Press release, Theseus Pharmaceuticals, OCT 6, 2021, View Source [SID1234590871]). All of the shares are being offered by Theseus. The gross proceeds to Theseus from the offering, before deducting underwriting discounts, commissions and other offering expenses payable by Theseus, are expected to be $160 million. In addition, Theseus has granted the underwriters a 30-day option to purchase up to an additional 1,500,030 shares of common stock from Theseus at the initial public offering price less underwriting discounts and commissions.

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Theseus’s common stock is expected to begin trading on The Nasdaq Global Select Market under the ticker symbol "THRX" on October 7, 2021. The offering is expected to close on or about October 12, 2021, subject to the satisfaction of customary closing conditions.

Jefferies, SVB Leerink and Cantor are acting as joint book-running managers for the offering. Wedbush PacGrow is acting as lead manager.

A registration statement relating to the securities being sold in the offering was declared effective by the Securities and Exchange Commission ("SEC") on October 6, 2021. The offering is being made only by means of a written prospectus. Copies of these documents can be accessed by visiting the SEC website at View Source Alternatively, copies of the final prospectus relating to the offering can be obtained, when available, from Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor, New York, NY 10022, by telephone at (877) 821-7388, or by email at [email protected]; SVB Leerink LLC, Attention: Syndicate Department, 53 State Street, 40th Floor, Boston, MA 02109, by telephone at (800) 808-7525, ext. 6105, or by email at [email protected]; Cantor Fitzgerald & Co., Attention Capital Markets, 499 Park Avenue, 4th Floor, New York, NY 10022, or by e-mail at [email protected].

This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

BIO-Europe, 25-28 October 2021

On October 6, 2021 Sijme Zeilemaker, CEO of Immunetune, reported that it will be attending BIO-Europe, taking place October 25-28, 2021, in digital format (Press release, ImmuneTune, OCT 6, 2021, View Source [SID1234590854]). Feel free to reach out to us to set up a meeting and explore collaboration and investment opportunities.

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Citius Pharmaceuticals to Present at Upcoming October Investor Conferences

On October 6, 2021 Citius Pharmaceuticals, Inc. ("Citius" or the "Company") (Nasdaq: CTXR), a late-stage biopharmaceutical company dedicated to the development and commercialization of first-in-class critical care products with a focus on oncology, anti-infective products in adjunct cancer care, unique prescription products, and stem cell therapies, reported that it will present at two investor conferences during the month of October 2021 (Press release, Citius Pharmaceuticals, OCT 6, 2021, View Source [SID1234590872]).

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EVENT: Benzinga Rising Stars: Catalytic Small Cap Growth Conference
DATE: Thursday, October 7, 2021
Citius Executive Chairman Leonard Mazur will present at 9:05 a.m. ET. His presentation will be available for viewing on Benzinga’s live stream channel.

EVENT: Dawson James Securities 6th Annual Small Cap Growth Conference
DATE: Thursday, October 21, 2021
Citius Executive Chairman Leonard Mazur will present at 8:55 a.m. ET in Track 1 and will be available for 1-on-1 meetings with registered conference attendees. The conference will be held October 20-21 at the Wyndham Grand Jupiter at Harbourside Place in Jupiter, Florida. A webcast of the presentation will be available on the Events page of the Citius Investors website.

At the conferences, Mr. Mazur will discuss the Company’s growing pipeline of therapies targeting unmet medical needs consisting of two late-stage assets completing Phase 3 trials, three potential first-and-only prescription treatments in their indications, and a next-generation stem cell therapy program.