On October 5, 2021 CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, reported that management will host a virtual event on October 12, 2021 at 4:30 p.m. ET to highlight clinical data from its ongoing Phase 1 CARBON trial assessing the safety and efficacy of CTX110, its wholly-owned allogeneic chimeric antigen receptor T cell (CAR-T) investigational therapy targeting CD19, for the treatment of relapsed or refractory B-cell malignancies(Press release, CRISPR Therapeutics, OCT 5, 2021, View Source [SID1234590813]).

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Conference Call and Webcast
To access the conference call, please dial +1 (866) 952-8559 (domestic) or +1 (785) 424-1743 (international) and reference the conference ID "CRISPR."

A live webcast of the event will be available on the "Events & Presentations" page in the Investors section of the Company’s website at View Source A webcast replay will be available on the CRISPR Therapeutics website after the event and will be archived for 14 days.

About CTX110
CTX110, a wholly owned program of CRISPR Therapeutics, is a healthy donor-derived gene-edited allogeneic CAR-T investigational therapy targeting Cluster of Differentiation 19, or CD19. CTX110 is being investigated in the ongoing CARBON trial.

About CARBON
The ongoing Phase 1 single-arm, multi-center, open label clinical trial, CARBON, is designed to assess the safety and efficacy of several dose levels of CTX110 for the treatment of relapsed or refractory B-cell malignancies.

On October 5, 2021 NOXXON Pharma N.V. (Euronext Growth Paris: ALNOX), a biotechnology company focused on improving cancer treatments by targeting the tumor microenvironment (TME), reported that new data from the ongoing Phase I/II GLORIA trial in brain cancer will be presented by Dr. Frank Giordano, the principal investigator of the study, in an oral presentation at the Society for Neuro-Oncology Annual Meeting (Press release, NOXXON, OCT 5, 2021, View Source [SID1234590853]). The meeting will take place in Boston, Massachusetts, US from November 18 – 21, 2021.

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Details of the oral presentation are as follows:

Title: CXCL12 inhibition in MGMT unmethylated glioblastoma – results of an early proof-of-concept assessment in the multicentric phase I/II GLORIA trial (NCT04121455)
Session Title: Abstract Session: Clinical Trials I
Session Date: Friday, November 19, 2021
Presentation Time: 05:00 – 05:05 p.m. EST / 11:00 – 11:05 p.m. CET
Presenter: Dr. Frank Giordano, Director and Chair of the Department of Radiation Oncology at the University Hospital Bonn, Germany

The embargo for abstracts published in the 2021 abstract supplement to the SNO official journal Neuro-Oncology will lift at 07:00 a.m.EST on Thursday, November 11, 2021 and the abstract will be made available at: View Source

To register to the event, please click here.

A copy of the presentation will be available on NOXXON’s website shortly after the event.

On October 5, 2021 Orion reported that it will publish Interim Report for January–September 2021 on Wednesday, 20 October 2021 at approximately 12.00 noon EEST (Press release, Orion , OCT 5, 2021, View Source [SID1234590835]). The release and related presentation material will be available on the company’s website at www.orion.fi/en/investors after publishing.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Webcast and conference call

A webcast and a conference call for analysts, investors and media will be held on Wednesday, 20 October 2021 at 13.30 EEST. The event will be held only online and by conference call.

A link to the live webcast will be available on Orion’s website at www.orion.fi/en/investors. A recording of the event will be available on the website later the same day.

On October 5, 2021 NovoCodex Pharma reported positive interim data from a China trial of its lead drug in patients with HER2+ metastatic gastric / gastroesophageal junction (GEJ) cancer(Press release, NovoCodex Biopharmaceuticals, OCT 5, 2021, View Source [SID1234590815]). ARX788 is an antibody-drug conjugate composed of an EGFR antibody targeting EGFR2 and HER2, joined to a apoptosis molecule. The candidate showed a tolerable safety profile and promising efficacy data. NovoCodex acquired China rights to ARX788 from Ambrx, a San Diego biotech. NovoCodex is a majority owned subsidiary of Zhejiang Medicine.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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On October 5, 2021 Harpoon Therapeutics, Inc. (NASDAQ: HARP), a clinical-stage immunotherapy company developing a novel class of T cell engagers, reported that an abstract with preclinical data of its TriTAC-XR T cell engager platform has been accepted for poster presentation at the 36th Annual Meeting of the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) (Press release, Harpoon Therapeutics, OCT 5, 2021, View Source [SID1234590836]). The meeting will be held virtually and in person in Washington, D.C. from November 10-14, 2021.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Abstract details:

Title: TriTAC-XR is an extended-release T cell engager platform designed to minimize cytokine release syndrome by reducing Cmax in systemic circulation
Abstract #: 867
Author: Kathryn S. Kwant, Ph.D., et al.
Session Category: Novel Single-Agent Immunotherapies
Poster Presentation Date and Time: November 12, 7 a.m. – 8:30 p.m. ET

The full abstract will be released on November 9, 2021 at 8 a.m. ET and the poster will be available on Harpoon’s website following the presentation.

For more details about the SITC (Free SITC Whitepaper) Virtual Annual Meeting please visit: View Source