Curis to Present at Upcoming Healthcare Conferences in September

On September 2, 2021 Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development of innovative therapeutics for the treatment of cancer, reported that James Dentzer, President and Chief Executive Officer of Curis, will participate in the following upcoming conferences (Press release, Curis, SEP 2, 2021, View Source [SID1234587178]):

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Morgan Stanley Virtual Global Healthcare Conference on Friday, September 10, 2021 at 11:00 a.m. ET
Cantor Virtual Global Healthcare Conference on Thursday, September 30, 2021 at 9:20 a.m. ET.
A live webcast of the presentation will be available under "Events & Presentations" in the Investors section of the Company’s website at www.curis.com. A replay of the webcast will be available on the Curis website for approximately 90 days following the event.

TYME Technologies, Inc. to Present at Upcoming Virtual Healthcare Industry Conferences

On September 2, 2021 TYME Technologies, Inc. (Nasdaq: TYME) (the "Company" or "TYME"), an emerging biotechnology company developing cancer metabolism-based therapies (CMBTs), reported that Richie Cunningham, Chief Executive Officer, and Frank Porfido, Chief Financial Officer, will present virtually at two upcoming healthcare conferences as follows (Press release, TYME, SEP 2, 2021, View Source [SID1234587197]):

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H.C. Wainwright 23rd Annual Global Investment Conference

Date:

Monday, September 13, 2021

Time:

On demand beginning at 7:00am ET

Webcast:

View Source

2021 Cantor Virtual Global Healthcare Conference

Date:

Thursday, September 30, 2021

Time:

10:40am ET

Webcast:

View Source

The webcasts will be accessible on the Events & Presentations page of the Investors section of the TYME website, tymeinc.com, and will be archived for 90 days following the events.

Syndax Announces Participation at Three Upcoming Investor Conferences

On September 2, 2021 Syndax Pharmaceuticals, Inc. ("Syndax," the "Company" or "we") (Nasdaq: SNDX), a clinical stage biopharmaceutical company developing an innovative pipeline of cancer therapies, reported that members of its management team will participate in three upcoming virtual investor conferences (Press release, Syndax, SEP 2, 2021, View Source [SID1234587213]):

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A fireside chat at the Morgan Stanley 19th Annual Global Healthcare Conference at 9:30 a.m. ET on Thursday, September 9, 2021.
A panel at the Citi 16th Annual BioPharma Virtual Conference at 9:45 a.m. ET on Friday, September 10, 2021.
A fireside chat at the Baird Global Healthcare Conference at 8:30 a.m. ET on Tuesday, September 14, 2021.
A live webcast of the Morgan Stanley presentation and Citi panel can be accessed from the Investor section of the Company’s website at www.syndax.com, where a replay of the events will also be available for a limited time.

Acquisition of Voluntis’ shares by AptarGroup,Inc

On September 2, 2021 Voluntis (Euronext Growth Paris, Ticker: ALVTX – ISIN: FR0004183960), a leader in digital therapeutics, and its reference shareholders (Bpifrance Participations, LBO France Gestion, Debiopharm Innovation Fund, SHAM Innovation Santé, Vesalius Biocapital and Indigo) reported that following the signature of a share purchase agreement with AptarGroup, Inc. (NYSE: ATR) ("Aptar") on July 22, 2021 and the approval of the French Ministry of Economy under the foreign investment clearance regulations, Aptar has completed the acquisition of a majority stake in Voluntis from the company’s reference shareholders and certain members of the management, representing approximately 64.6% of the share capital of Voluntis (on a non-diluted basis), at a price of €8.70 per share (Press release, Debiopharm, SEP 2, 2021, View Source [SID1234587255]).

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In accordance with applicable regulation, Aptar will launch a mandatory cash tender offer to acquire Voluntis’ remaining shares for the same price of €8.70 per share (the "Tender Offer"). The Tender Offer is intended to be filed with the French Markets Authority (the "AMF") in September 2021 and will be subject to the regulatory clearance from the AMF.

If the regulatory conditions are met upon completion of the Tender Offer, Aptar intends to implement a squeeze-out on the remaining outstanding shares of Voluntis. Voluntis’ board of directors (the "Board"), upon the recommendation of its ad hoc committee and in accordance with applicable regulation, appointed Advolis Orfis as independent expert on July 5, 2021, and will issue, notably on the basis of the independent expert’s report opining on the financial terms of the Tender Offer and potential subsequent squeeze-out, a reasoned opinion on the Tender Offer and its consequences on Voluntis, its shareholders and employees.

The independent expert’s report and the Board’s opinion will be included in the draft response offer document that will be prepared by Voluntis in the context of the Tender Offer and submitted to the AMF, which will assess its compliance with applicable regulation.

On September 2, 2021, following resignation of the selling shareholders’ representatives on the Voluntis Board, namely Laurent Higueret (representative of Bpifrance Participations) and Franck Noiret (representative of LBO France Gestion), Gael Touya and Patrick Jeukenne, Aptar’s representatives, have been appointed to replace them in the Board.

The Board has also appointed M. Sai Shankar as deputy CEO of Voluntis, and the current management of Voluntis is otherwise expected to remain the same following the completion of the Tender Offer.

In addition, Voluntis announces that it has fully repaid in advance the bond loan subscribed with Kreos for an amount of € 0.75 million

Positive Results from the Scandion Oncology and Alligator Bioscience Collaboration Further Supports Efficacy of Mitazalimab in Combination Therapy

On September 2, 2021 Alligator Bioscience AB (Nasdaq Stockholm: ATORX) and Scandion Oncology A/S (Nasdaq Stockholm: SCOL), reported the conclusion of their collaboration with a very positive outcome (Press release, Alligator Bioscience, SEP 2, 2021, View Source [SID1234587143]).

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The purpose of the collaboration was to explore the anti-tumor efficacy of the CD40 antibody mitazalimab in chemotherapy-resistant preclinical tumor models as an addition to chemotherapy (FOLFIRINOX) combined with SCO-101. The hypothesis that was tested was to see if SCO-101, as compared to saline control will revert chemotherapy resistance and thereby facilitate a strengthening of the anti-tumor effects of mitazalimab. After the final data has been evaluated, the joint feasibility study have reached all goals of the cooperation and the companies have now concluded the collaboration.

"The feasibility study supported our hypothesis and opens the door for harvesting the value of this successful study with larger players. Both Scandion Oncology and Alligator have limited resources and our joint intention was to support the hypothesis, which now has been achieved. We remain committed to further exploring the potential of SCO-101 in immuno-oncology," said Bo Rode Hansen, President and CEO of Scandion Oncology.

"We were pleased to see that the results strengthen and expand the preclinical efficacy data for mitazalimab by demonstrating synergy with FOLFIRINOX in tumors resistant to chemotherapy. We are committed to develop mitazalimab in hard-to-treat cancer, and this data is very valuable in continuing to assess the efficacy of mitazalimab as a combination therapy with FOLFIRINOX in pancreatic cancer in our OPTIMIZE-1 phase II study," said Søren Bregenholt, CEO of Alligator Bioscience.

As announced in June 2021, the combination of mitazalimab and FOLFIRINOX, in pre-clinical trials, demonstrated a strong anti-tumor response in FOLFIRINOX resistant cancer cells and indicated that the anti-tumor effect of SCO-101, mitazalimab and FOLFIRINOX is even more potent than mitazalimab and FOLFIRINOX. The data support the basic concept that SCO-101 in combination with chemotherapy and immuno-oncology is well tolerated and has a very potent anti-tumor effect in vivo on drug resistant cancer cells. The data further validate the potential of mitazalimab in combination with standard of care chemotherapy such as FOLFIRINOX.