On September 2, 2021 Alligator Bioscience AB (Nasdaq Stockholm: ATORX) and Scandion Oncology A/S (Nasdaq Stockholm: SCOL), reported the conclusion of their collaboration with a very positive outcome (Press release, Alligator Bioscience, SEP 2, 2021, View Source [SID1234587143]).

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The purpose of the collaboration was to explore the anti-tumor efficacy of the CD40 antibody mitazalimab in chemotherapy-resistant preclinical tumor models as an addition to chemotherapy (FOLFIRINOX) combined with SCO-101. The hypothesis that was tested was to see if SCO-101, as compared to saline control will revert chemotherapy resistance and thereby facilitate a strengthening of the anti-tumor effects of mitazalimab. After the final data has been evaluated, the joint feasibility study have reached all goals of the cooperation and the companies have now concluded the collaboration.

"The feasibility study supported our hypothesis and opens the door for harvesting the value of this successful study with larger players. Both Scandion Oncology and Alligator have limited resources and our joint intention was to support the hypothesis, which now has been achieved. We remain committed to further exploring the potential of SCO-101 in immuno-oncology," said Bo Rode Hansen, President and CEO of Scandion Oncology.

"We were pleased to see that the results strengthen and expand the preclinical efficacy data for mitazalimab by demonstrating synergy with FOLFIRINOX in tumors resistant to chemotherapy. We are committed to develop mitazalimab in hard-to-treat cancer, and this data is very valuable in continuing to assess the efficacy of mitazalimab as a combination therapy with FOLFIRINOX in pancreatic cancer in our OPTIMIZE-1 phase II study," said Søren Bregenholt, CEO of Alligator Bioscience.

As announced in June 2021, the combination of mitazalimab and FOLFIRINOX, in pre-clinical trials, demonstrated a strong anti-tumor response in FOLFIRINOX resistant cancer cells and indicated that the anti-tumor effect of SCO-101, mitazalimab and FOLFIRINOX is even more potent than mitazalimab and FOLFIRINOX. The data support the basic concept that SCO-101 in combination with chemotherapy and immuno-oncology is well tolerated and has a very potent anti-tumor effect in vivo on drug resistant cancer cells. The data further validate the potential of mitazalimab in combination with standard of care chemotherapy such as FOLFIRINOX.

On September 2, 2021 Supernus Pharmaceuticals, Inc. (Nasdaq: SUPN), a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases, reported that the Company’s management will participate and host investor meetings in the following upcoming September 2021 virtual investor conferences (Press release, Supernus, SEP 2, 2021, View Source [SID1234587163]).

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Citi’s 16th Annual BioPharma Virtual Conference
Date: Thursday, September 9, 2021
Participation Type: One-on-one meetings

Wells Fargo 2021 Virtual Healthcare Conference
Date: Friday, September 10, 2021
Participation Type: Presentation
Presentation Time: 9:20 a.m. ET

Morgan Stanley 19th Annual Global Healthcare Conference
Date: Wednesday, September 15, 2021
Participation Type: Fireside Chat
Presentation Time: 11:45 a.m. ET

A live webcast of the events can be accessed by visiting Events & Presentations in the Investor Relations section on the Company’s website at www.supernus.com. An archived replay of each webcast will be available for 60 days on the Company’s website after the respective conference.

On September 2, 2021 Jounce Therapeutics, Inc. (NASDAQ: JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, reported that company management will participate at several upcoming investor conferences in September (Press release, Jounce Therapeutics, SEP 2, 2021, View Source [SID1234587179]):

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2021 Wells Fargo Virtual Healthcare Conference: Fireside chat on Friday September 10, 2021 at 8:00 a.m. ET.
H.C. Wainwright 23rd Annual Global Investment Conference: Presentation will be available on-demand during the conference, starting on Monday, September 13, 2021 at 7:00 a.m. ET.
Baird’s 2021 Global Healthcare Conference: Presentation on Wednesday, September 15, 2021 at 12:15 p.m. ET.
2021 Cantor Fitzgerald Virtual Global Healthcare Conference: Presentation on Wednesday, September 29, 2021 at 4:00 p.m. ET.
A webcast of the presentations will be available by visiting "Events and Presentations" in the Investors and Media section of Jounce’s website at www.jouncetx.com. A replay of the webcasts will be archived for 30 days following the presentation.

On September 2, 2021 Repare Therapeutics Inc. ("Repare" or the "Company") (Nasdaq: RPTX), a leading clinical-stage precision oncology company enabled by its proprietary synthetic lethality approach to the discovery and development of novel therapeutics, reported that members of its senior management team will participate in a fireside chat at the 19th Annual Morgan Stanley Virtual Global Healthcare Conference on Thursday, September 9 at 2:45 p.m. Eastern Time (Press release, Repare Therapeutics, SEP 2, 2021, View Source [SID1234587198]).

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A live webcast of the fireside chat can be accessed in the Investor section of the Company’s website at View Source A replay of the webcast will be archived on the Company’s website for 30 days.

On September 2, 2021 Almac Group reported that Khadeeja Ali Syeda, a 2021 graduate of Apex Friendship High School, has been selected as the recipient of the inaugural Almac Group Scholarship, and will receive $50,000 over the next four years (Press release, Almac, SEP 2, 2021, View Source [SID1234587217]).

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After an independent review by Triangle Community Foundation’s seasoned scholarship committee, Khadeeja was named this year’s recipient due to her impressive academic performance and involvement in the community, interest in pursuing a STEM career, and powerful personal statement. She will attend North Carolina State University and will receive, in addition to tuition assistance, mentorship opportunities and unique exposure to Almac Group’s career opportunities in the global pharmaceutical and biotech industry.

Commented Donna Christopher, Global VP of Operations, Almac Clinical Services, "Almac and the McClay Foundation support students in overcoming barriers to education across the world, and I am so pleased that we have expanded our reach to create opportunity here in the Triangle region. On behalf of Almac, we are excited to offer the inaugural Almac Group Scholarship to Khadeeja Ali Syeda, whom we had the recent pleasure of meeting at our facility in Durham prior to her first day at North Carolina State University. She is an impressive student who is well-prepared to succeed, and we look forward to continuing to forge a relationship with her as we provide support to help chart her success during her college career and beyond."

Commented Khadeeja Ali Syeda, ""I would like to thank Almac for their generosity. This scholarship will alleviate much of the financial burden I had due to the cost of my education, and will make it easier for me to pursue my goals. I am honored to have been the recipient of this award, and I am excited for the opportunities it will open up for me in the future."

The Almac Group Scholarship Fund was established in Spring2021 in partnership with Triangle Community Foundation to support a substantial, multi-year scholarship award for a selected first-year college student in the Triangle region. Triangle Community Foundation is responsible for scholarship administration and independent evaluation of scholarship candidates, and the McClay Foundation, which wholly owns the Almac Group, is the sole financier of the Fund and its subsequent awards, including this year’s award.

Commented Julia Da Silva, Scholarships Officer at Triangle Community Foundation, "We’re thrilled to be able to partner with Almac Group to support Khadeeja through her college journey and see her join our community of scholars. We can’t wait to see the positive impact she will have on her community and the amazing things she will do with the degree she has chosen to pursue."

The McClay Foundation was established by the late Sir Allen McClay, one of Northern Ireland’s most distinguished entrepreneurs and philanthropists and founder of Almac Group, with the vision to "make a meaningful improvement and advance human health," through the contributions of Almac Group’s innovative family of companies and support to a wide range of global charitable organizations.