On February 17, 2021 NexImmune, Inc. (Nasdaq: NEXI), a clinical-stage biotechnology company developing a novel approach to immunotherapy designed to employ the body’s own T cells to generate a specific, potent and durable immune response, reported the closing of its previously announced upsized initial public offering of 7,441,650 shares of its common stock at a price to the public of $17.00 per share, which includes the exercise in full by the underwriters of their option to purchase 970,650 additional shares (Press release, NexImmune, FEB 17, 2021, View Source [SID1234576168]). Including the option exercise, the gross proceeds to NexImmune from the offering, before deducting the underwriting discounts and commissions and estimated offering expenses, were approximately $126.5 million.

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Barclays Capital Inc., Cantor Fitzgerald & Co., Raymond James & Associates, Inc. and Allen & Company LLC acted as the joint book-running managers for the offering.

Registration statements relating to these securities have been filed with the Securities and Exchange Commission and became effective on February 11, 2021. The offering was made only by means of a prospectus. Copies of the final prospectus related to the offering may be obtained from: Barclays Capital Inc., Attention: Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, New York 11717, telephone: (888) 603-5847, or email: [email protected]; Cantor Fitzgerald & Co., Attention: Capital Markets Department, 499 Park Avenue, New York, NY 10022, or email: [email protected]; Raymond James & Associates, Inc., Attention: Equity Syndicate, 880 Carillon Parkway, St. Petersburg, FL 33716, telephone: (800) 248-8863, or email: [email protected]; or Allen & Company LLC., Attention: Prospectus Department, 711 Fifth Avenue, New York, NY 10022, telephone: (212) 339-2220, or email: [email protected].

This press release shall not constitute an offer to sell or a solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

On February 17, 2021 Micronoma, the first cancer detection biotech company that utilizes signals from the tumor-related microbiome to diagnose cancer at an early stage with liquid biopsy technology, reported the closing of $3.5 million in convertible debt financing (Press release, Micronoma, FEB 17, 2021, View Source [SID1234575167]). The contributions came from existing investor, US-based SymBiosis, LLC, and new European investor, The Seerave Foundation. The investments bring Micronoma’s total amount of funding to $6.5 million since the company’s first seed round six months ago.

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Micronoma decrypts signals from some of the most ancient matter in the world, the microbiome, to detect cancer early, from all genomes. The additional financing will enable Micronoma to complete its validation study on lung cancer prediction, set up CLIA (Clinical Laboratory Improvement Amendments) operations, establish its go-to-market strategy utilizing its Oncobiota platform, and initiate work on a second cancer target.

"The Seerave Foundation is a strong supporter of efforts enabling personalized cancer treatments. We are confident that the nutrition-microbiome-immune system axis is a significant factor in each patient’s journey," said David Rees, founder of The Seerave Foundation. "Thus, we recognize early diagnosis of cancer-associated microbial DNA as a key element to transforming cancer diagnostics and treatment going forward. We are convinced that the Micronoma platform will complement our other research activities and help in translating scientific innovations for practical applications. We are interested in being able to enhance the standard of care with a more holistic and patient-centric approach. Our ultimate goal is to move from a therapeutic into a preventive setting of personalized medicine which is where Micronoma’s innovation and expertise come into play, to empower physicians with actionable biomarkers."

Micronoma’s promising research was published in Nature last year, showing unique predictive microbial signatures in tissue and blood for most major types of cancer. Accurate, early cancer detection via liquid biopsy remains a challenge that Micronoma may be able to solve through its proprietary Oncobiota platform. Though having the potential to be a pan-cancer diagnostic tool, Micronoma will start with lung cancer, and with this recent funding, move toward pancreatic cancer diagnostics.

"We are grateful for the continued and new support from like-minded organizations that are as dedicated as we are to finding innovative and precise ways to significantly improve early cancer diagnosis," said Sandrine Miller-Montgomery, CEO of Micronoma. "SymBiosis has been an amazing partner and we are so happy to now have Seerave, expanding our support globally. Together, we can expand the limits of care and revolutionize what practitioners and patients have come to understand as status quo. We are all very passionate about bringing this technology to market as quickly and thoroughly as possible."

Each year, there are approximately 18 million new cancer cases worldwide and nine million cancer deaths. It is estimated that with early detection, up to 4 million of those deaths could be prevented every year. The diagnostic implications of microbiome markers in liquid and tissue biopsies are extensive, and Micronoma is prepared to lead the way on helping prevent unnecessary suffering caused by later-stage cancer diagnosis.

On February 17, 2021 Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE), a biopharmaceutical company focused on the development and commercialization of novel products for serious rare and ultra-rare genetic diseases, reported that Emil D. Kakkis, M.D., Ph.D., the company’s Chief Executive Officer and President, will present at the following upcoming investor conferences (Press release, Ultragenyx Pharmaceutical, FEB 17, 2021, View Source [SID1234575185]):

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SVB Leerink 10th Annual Global Healthcare Conference on Wednesday, February 24, 2021 at 2:20 PM ET.

Cowen 41st Annual Health Care Conference on Monday, March 1, 2021 at 2:00 PM ET.
The live and archived webcast of the presentation will be accessible from the company’s website at View Source The replay of the webcast will be available for 90 days.

On February 17, 2021 BioLineRx Ltd. (NASDAQ: BLRX) (TASE: BLRX), a late clinical-stage biopharmaceutical company focused on oncology, reported it will release its audited financial results for the year ended December 31, 2020 on Tuesday, February 23, 2021, before the US markets open (Press release, BioLineRx, FEB 17, 2021, View Source [SID1234575202]).

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The Company will host a conference call on Tuesday, February 23, 2021 at 10:00 a.m. EST featuring remarks by Philip Serlin, Chief Executive Officer, and other members of the management team. The conference call will be available via webcast and can be accessed through the Investor Relations page of BioLineRx’s website. Please allow extra time prior to the call to visit the site and download any necessary software to listen to the live broadcast.

To dial into the conference call, please dial +1-866-744-5399 from the US or +972-3-918-0610 internationally. A replay of the conference call will be available approximately two hours after completion of the live conference call on the Investor Relations page of BioLineRx’s website. A dial-in replay of the call will be available until February 25, 2021; please dial +1-888-782-4291 from the US or +972-3-925-5904 internationally.

On February 17, 2021 Jazz Pharmaceuticals plc (Nasdaq: JAZZ) reported that the company will webcast its corporate presentation at the Leerink 10th Annual Global Healthcare Conference (Press release, Jazz Pharmaceuticals, FEB 17, 2021, View Source [SID1234575221]).

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Bruce Cozadd, chairman and chief executive officer, will provide an overview of the company and a business and financial update on Wednesday, February 24, 2021 at 1:40 p.m. EST / 6:40 p.m. GMT.

A live audio webcast of the presentation may be accessed from the Investors section of the Jazz Pharmaceuticals website at www.jazzpharmaceuticals.com. Please connect to the website prior to the start of the presentation to ensure adequate time for any software downloads that may be necessary to listen to the webcast.

An archive of the webcast will be available following the presentation for at least one week on the Investors section of the company’s website at www.jazzpharmaceuticals.com.