Rocket Pharmaceuticals to Host Conference Call on Aug. 9 at 4:30 p.m. ET to Discuss Second Quarter Results and Recent Business Highlights

On August 3, 2021 Rocket Pharmaceuticals, Inc. (NASDAQ: RCKT), a clinical-stage company advancing an integrated and sustainable pipeline of genetic therapies for rare childhood disorders, reported that it will host a conference call and live audio webcast on Monday, Aug. 9, 2021, at 4:30 p.m. ET to report second quarter 2021 financial results and recent business highlights (Press release, Rocket Pharmaceuticals, AUG 3, 2021, View Source [SID1234585647]).

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Investors may access the conference call by dialing (866) 939-3921 from locations in the United States or +1 (678) 302-3550 from outside the United States. Please refer to conference ID number 50210581. A live webcast of the call can be accessed under "Events" in the Investors section of the Company’s website at View Source

The webcast replay will be available on the Rocket website following the completion of the call.

Sprint Bioscience licenses the cancer drug program Vps34 to Deciphera Pharmaceuticals

On August 3, 2021 Sprint Bioscience AB (publ) reported that the company has licensed its cancer drug program Vps34 to the US pharmaceutical company Deciphera Pharmaceuticals (Press release, Sprint Bioscience, AUG 3, 2021, View Source [SID1234585600]). The license agreement covers exclusive global rights to the program. The agreement has a total potential value of up to USD 277 million, plus additional tiered percentage royalties ranging from the mid-single-digits to the low-double-digits on the sales of a future drug from the program, if approved. On signing of the agreement, Sprint Bioscience will receive an upfront payment of USD 4 million, which will be entered into the accounts for the third quarter of 2021.

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The chosen partner, Deciphera Pharmaceuticals Inc., founded in 2003, is a pharmaceutical company focused on delivering important new medicines to patients for the treatment of cancer. The company has an approved product on the market in multiple geographies, as well as three product candidates in clinical development. The company is listed on the Nasdaq Global Select Market with a market cap of approximately USD 2 billion. With a clear focus on improving the lives of people living with cancer and demonstrated expertise in bringing a new drug to market, Deciphera is considered to be an extremely attractive partner for the Sprint Biosciences Vps34 program. Deciphera will assume full responsibility for resource allocation as it continues research efforts, and for taking the program to the clinic and further onto the market.

"Today’s announcement represents Deciphera’s focus to discover, develop, and deliver important new medicines to patients for the treatment of cancer, as well as an effort to complement our robust internal research programs with partnership opportunities such as this one. This Vps34 program fits well with our growing pipeline, and enhances our efforts to explore the potential for regulating autophagy in cancer," said Dan Flynn, Executive Vice President and Chief Scientific Officer (CSO) of Deciphera Pharmaceuticals.

Deciphera will now take over the program’s continued development and all associated costs.

"The licensing agreement with Deciphera Pharmaceuticals is the most comprehensive to date that Sprint Bioscience has signed and further proof of our ability to continuously generate groundbreaking programs with great commercial potential. We have an increasing number of programs in our portfolio where well-funded partners take over responsibility and all costs for continued development at an early stage, while we are eligible for milestone payments when the programs achieve predetermined goals. As the number of out-licensed programs increases and further develops, we create more and more opportunities for revenues. The total revenue potential from our active licensing agreements has now increased to approximately USD 747 million, plus royalty payments," said Erik Kinnman, CEO of Sprint Bioscience.

In addition to the upfront payment, Sprint Bioscience is entitled to payments linked to predefined milestones during the project’s further development, regulatory process and commercialization of a drug. With the upfront, the total value of these payments amounts up to USD 277 million.Should the program result in an approved drug, Sprint Bioscience is also entitled to tiered percentage royalties ranging from the mid-single-digits to the low-double-digits on the sales of a future drug from the program, if approved.

This disclosure contains information that Sprint Bioscience is obliged to make public pursuant to the EU Market Abuse Regulation (EU nr 596/2014). The information was submitted for publication, through the agency of the contact person, on 03-08-2021 22:15 CET.

Karyopharm Announces Upcoming Virtual Investor Conference Participation

On August 3, 2021 Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, reported that Richard Paulson, President and Chief Executive Officer, will participate on a speaker panel at the 2021 Wedbush PacGrow Healthcare Virtual Conference titled, "Building Back a Better Commercial Infrastructure – Selling in COVID Times" and participate in a fireside chat at the Canaccord Genuity 41st Annual Growth Conference (Press release, Karyopharm, AUG 3, 2021, View Source [SID1234585616]). Details regarding these upcoming virtual investor conferences are below.

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2021 Wedbush PacGrow Healthcare Virtual Conference
Date: Tuesday, August 10, 2021
Time: 8:35 AM Eastern Time

Canaccord Genuity 41st Annual Growth Conference
Date: Thursday, August 12, 2021
Time: 3:30 PM Eastern Time

A live webcast of the panel and fireside chat can be accessed under "Events & Presentations" in the Investor section of the Company’s website, View Source A replay of the webcasts will be archived on the Company’s website for 30 days following the panel and fireside chat.

Arbutus to Present at Wedbush PacGrow Healthcare Virtual Conference

On August 3, 2021 Arbutus Biopharma Corporation (Nasdaq: ABUS), a clinical-stage biopharmaceutical company primarily focused on discovering, developing and commercializing a cure for people with chronic hepatitis B virus (HBV) infection, as well as therapies to treat coronaviruses (including COVID-19), reported that the Company will participate in a fireside chat at the Wedbush PacGrow Healthcare Virtual Conference on Tuesday, August 10, 2021 at 4:05 PM ET.

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Arbutus Fireside Chat Presenters:

William Collier, President and CEO; Dr. Michael Sofia, Chief Scientific Officer; Dr. Gaston Picchio, Chief Development Officer; and David Hastings, Chief Financial Officer.

A live webcast of the fireside chat can be accessed through the Investors section of Arbutus’ website at www.arbutusbio.com or directly at Live Webcast. An archived replay of the webcast will be available on the Company’s website after the conference.

Announcement of Consolidated Financial Results Fiscal 2021 Second Quarter

On August 3, 2021 Kyowa Hakko Kirin reported (Press release, Kyowa Hakko Kirin, AUG 3, 2021, View Source [SID1234585586])

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1. Consolidated Financial Results for the Six Months Ended June 30, 2021

(2) Consolidated financial position

2. Dividends

3. Consolidated Earnings Forecasts for the Fiscal Year Ending December 31, 2021 (from January 1, 2021 to December 31, 2021) Quarterly financial results reports are exempt from quarterly review conducted by certified public accountants or an audit corporation. * Notice regarding the appropriate use of the earnings forecasts and other special comments

The forward-looking statements, including earnings forecasts, contained in these materials are based on the information currently available to the Company and on certain assumptions deemed to be reasonable by management. As such, they do not constitute guarantees by the Company of future performance. Actual results may differ materially from these projections for a wide variety of reasons.

1. Operating Results and Financial Statements
(1) Summary of Consolidated Financial Position

Assets as of June 30, 2021, were ¥819.8 billion, an increase of ¥18.5 billion compared to the end of the previous fiscal year.

 Non-current assets increased by ¥8.3 billion to ¥367.1 billion, due mainly to an increase in deferred tax assets, in addition to an increase in goodwill associated with the impact of yen depreciation.

 Current assets increased by ¥10.2 billion to ¥452.7 billion, due mainly to an increase in cash and cash equivalents resulting from the proceeds from sale of assets held for sale (shares of Hitachi Chemical Diagnostics Systems Co., Ltd.) as well as an increase in inventories, despite a decrease in assets held for sale.

Liabilities as of June 30, 2021, were ¥99.2 billion, a decrease of ¥3.7 billion compared to the end of the previous fiscal year, due mainly to a decrease in trade and other payables.

 Equity as of June 30, 2021, was ¥720.5 billion, an increase of ¥22.1 billion compared to the end of the previous fiscal year, due mainly to an increase due to the recording of profit attributable to owners of parent as well as an increase in exchange differences on translation of foreign operations resulting from the impact of exchange rates, despite a decrease due to the payment of dividends, etc. As a result, the ratio of equity attributable to owners of parent to total assets as of the end of the second quarter was 87.9%, an increase of 0.7 percentage points compared to the end of the previous fiscal year.

(2) Summary of Consolidated Business Performance

1) Overview of results The Group now applies the International Financial Reporting Standards ("IFRS") in line with its policy of expanding business globally, and adopts "core operating profit" as a level of profit that shows the recurring profitability from operating activities. Core operating profit is calculated by deducting "selling, general and administrative expenses" and "research and development expenses" from "gross profit," and adding "share of profit (loss) of investments accounted for using equity method" to the amount. For the six months ended June 30, 2021 (January 1, 2021 to June 30, 2021), revenue was ¥165.0 billion (up 4.6% compared to the same period of the previous fiscal year), and core operating profit was ¥30.9 billion (down 10.2%). Profit attributable to owners of parent was ¥25.1 billion (down 9.8%).

 The increase in revenue was the result of steady growth of global strategic products in North America and EMEA and strong sales in Asia, mainly in China, despite lower revenue in Japan. The positive effect on revenue from foreign exchange was ¥1.5 billion.

 The decrease in core operating profit was the result of increases in selling, general and administrative expenses, and research and development expenses, despite an increase in gross profit due to an increase in overseas revenue. The positive effect on core operating profit from foreign exchange was ¥0.2 billion. 

Profit attributable to owners of parent decreased as a result of an increase in income tax expense in addition to a decrease in core operating profit, despite a decrease in other expenses.