Novavax to Participate in H.C. Wainwright Virtual Global Life Sciences Conference Fireside Chat

On March 8, 2021 Novavax, Inc. (Nasdaq: NVAX), a biotechnology company developing next-generation vaccines for serious infectious diseases, reported that it will participate in a fireside chat during the H.C. Wainwright Virtual Global Life Sciences conference. Novavax’ COVID-19 vaccine candidate, NVX-CoV2373, will be the topic of discussion (Press release, Novavax, MAR 8, 2021, View Source [SID1234576335]).

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Fireside Chat details:
Date: Tuesday, March 9, 2021
Time: Available on-demand starting at 7:00 a.m. Eastern Time (ET)
Participants: Gregory M. Glenn, M.D., President, Research and Development and John Trizzino, Executive Vice President, Chief Commercial Officer and Chief Business Officer
A replay of the recorded fireside session will be available through the events page of the Company’s website at ir.novavax.com for 90 days.

Promatix launches to develop next generation novel oncology therapeutics

On 8 March 2021 ALSA Ventures reported the launch of Promatix Inc., a Delaware incorporated company, to develop novel therapeutics with the potential to transform the treatment of cancer (Press release, Promatix Biosciences, MAR 8, 2021, View Source [SID1234629078]). Promatix will use its multi-omic proprietary database, TxPro, to mine for novel, and validate existing, drug targets.

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"As we mark off the 20th anniversary of drafting the human genome, it’s clear we’re still in the early innings of a revolution in molecular biology. Taking a multi-omic approach to novel drug discovery, aided by advances in AI technology, Promatix will take a highly focused, data driven approach, to hunt for novel targets in oncology indications of unmet need"
Alek Safarian, Executive Chairman of Promatix

Building on two decades of development, chiefly in the proteomics space, Promatix will combine its proprietary platform, TxPro, with third party public and private databases to create a powerful multi-omic engine to help Identify novel targets for rapid early development.

Promatix will continue to be incubated in the near term within the ALSA Group, which is providing seed funding to establish its first suite of targeted research projects. Dr Robert Balfour, Investment Director at ALSA, and acting CEO at Promatix emphasised the importance of building on Promatix’s academic links as a guiding principle of its mission.

"Both for known targets, as well as discovering new ones, TxPro has the potential to make a significant contribution to the wider body of knowledge. We are delighted to be working with world class advisors in this endeavour, and are looking forward to establishing a robust pipeline of drug candidates"
Dr Robert Balfour, CEO

Scientific Advisory Board
Promatix’s advisors bring a wealth of knowledge across proteomics, oncology and computational biology.

Dr Jyoti Choudhary is head of the Proteomics Core Facility at the Institute of Cancer Research, UK. Her research focuses on the development and implementation of novel mass spectrometry and data analysis approaches for proteome discovery.

Professor Jasmin Fisher heads up The Fisher Lab at University College London. The Fisher Lab develops computational tools to study the evolution of cancer and the underlying mechanisms of cancer to identify personalised treatment for patients. Prior to joining UCL Jasmin was a Principal Researcher at Microsoft research in Cambridge, UK and an Associate Professor in Systems Biology at Cambridge University.

Dr Namshik Han is the Head of Computational Research Group at the University of Cambridge Milner Therapeutics Institute. The group develops and applies cutting edge computational methods such as artificial intelligence and machine learning to identify new therapies from the analysis of large multi-omic datasets. Prior to Cambridge, he was a post-doc in computational cancer genomics at the University of Manchester and worked in software development for Samsung Electronics.

Targovax to present and attend at upcoming investor and scientific conferences

On March 8, 2021 Targovax ASA, reported that members of its executive management team is invited to present and participate at upcoming conferences (Press release, Targovax, MAR 8, 2021, View Source [SID1234576177]).

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H.C. Wainwright Annual Global Life Sciences Conference, virtual
Date: 9 March 2021
Presenter: Øystein Soug (CEO)
Time: 13:00 CET

Carnegie Healthcare Seminar, virtual
Date: 12 March 2021
Presenter: Øystein Soug (CEO)
Time: 12:45 CET

Roth Capital 33rd Annual Conference, virtual
Date: 15-17 March 2021
1×1 meetings

Tumor Myeloid Microenvironment Directed Therapeutics, virtual
Date: 17 March
Presenter: Victor Levitsky (CSO)
Time: 22:45 CET

European Biotech Investor Days 2021, virtual
Date: 7-8 April 2021
Presenter: Øystein Soug (CEO)
Time: To be scheduled

GT Biopharma Announces Preclinical Results For Its ROR1 TriKE™ As A Treatment For Prostate Cancer

On March 8, 2021 GT Biopharma, Inc. (NASDAQ: GTBP), a clinical stage biopharmaceutical company focused on disruptive, target-directed Natural Killer (NK) cell engager immunotherapy technologies (TriKE) for cancer, reported preclinical results for its ROR1 TriKE product candidate as a prospective therapy for the treatment of prostate cancer (Press release, GT Biopharma, MAR 8, 2021, View Source [SID1234576198]).

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Tyrosine kinase transmembrane receptor ROR1 has recently been shown to be overexpressed on certain cancer cells, and appears to play a functional role in promoting migration/invasion and influencing the metastatic potential of various solid tumor cancers. Targeting ROR1 on cancer cells with TriKE and redirecting NK cells to attack and kill cancer cells expressing ROR1, could result in a therapeutic treatment that limits the metastatic potential and invasiveness of certain solid tumor cancers.

The ROR1 TriKE was evaluated in several preclinical models of prostate cancer, and was found to be effective at promoting NK cell killing of multiple prostate cancer cells including LnCAP, C4-2, PC-3, DU-145, VCaP and 22RV1. Significant NK cell activation and interferon gamma (IFNγ) production was also observed as a result of TriKE engagement and activation of the NK cell.

"We are pleased to report our ROR1 TriKE has passed this important preclinical milestone, and demonstrated effectiveness in promoting redirected and target-specific killing by NK cells," said Anthony J. Cataldo, GT Biopharma’s Chairman and Chief Executive Officer. "We plan to evaluate the ROR1 TriKE in additional IND-enabling preclinical studies with the goal of transitioning to a Phase I/II clinical trial."

Fate Therapeutics to Present at Upcoming Investor Conferences

On March 8, 2021 Fate Therapeutics, Inc. (the "Company" or "Fate Therapeutics") (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to the development of programmed cellular immunotherapies for cancer, reported that the Company will present at the following upcoming investor conferences (Press release, Fate Therapeutics, MAR 8, 2021, View Source [SID1234576215]):

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Barclays Global Healthcare Conference on Thursday, March 11, 2021 from 11:30-11:55AM ET
Oppenheimer Virtual 31st Annual Healthcare Conference on Wednesday, March 17, 2021 from 1:10-1:40PM ET
A live webcast, if recorded, of each presentation can be accessed under "Events & Presentations" in the Investors section of the Company’s website at www.fatetherapeutics.com. The archived webcast will be available on the Company’s website shortly after the event.