On May 25, 2021 AVEO Oncology (Nasdaq: AVEO) reported that Michael Bailey, president and chief executive officer of AVEO, will present at the Jefferies 2021 Virtual Healthcare Conference on Tuesday, June 1, 2021 at 2:30 p.m. Eastern Time (Press release, AVEO, MAY 25, 2021, View Source [SID1234580529]).

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A live webcast of the presentation can be accessed by visiting the investors section of the Company’s website at www.aveooncology.com. A replay of the webcast will be archived for 30 days following the presentation date.

On May 25, 2021 Isofol Medical AB’s (publ), (Nasdaq First North Premier Growth Market: ISOFOL), ("Isofol or the "Company") Board of Directors reported on May 18, 2021, on an issue of shares of a maximum of 62,524,474 shares with preferential rights for the Company’s existing shareholders (the "Rights Issue") (Press release, Isofol Medical, MAY 25, 2021, View Source [SID1234580546]). If the Rights Issue is fully subscribed, the Company will receive approximately SEK 400 million before transaction costs related to the Rights Issue. In connection with the Rights Issue, the Company publishes a prospectus which today has been approved and registered by the Swedish Financial Supervisory Authority (Sw. Finansinspektionen).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Not for publication, distribution or release, directly or indirectly, in whole or in part, within or into the United Kingdom, US, Canada, Japan, Australia, Hong Kong, New Zealand or any other jurisdiction in which such publication, distribution or release may be contravening to any applicable laws or rules. Additional restrictions are applicable, please see "Important information" in the end of this press release.

Timetable for the Rights Issue

Prospectus

For full information regarding the Rights Issue, please refer to the prospectus, which is available on Isofol’s website, www.isofolmedical.com. Link to the application form is available on the same link at the start of the subscription period at the latest, and on Carnegie Investment Bank AB (publ)’s website, www.carnegie.se. The prospectus is also available on the Swedish Financial Supervisory Authority’s (Sw. Finansinspektionen) website, www.fi.se.

Advisors

Carnegie Investment Bank AB (publ) and Pareto Securities AB act as Joint Bookrunners in connection with the Rights Issue. Vinge law firm acts as legal adviser to Isofol, and Schjødt law firm acts as legal adviser to the Joint Bookrunners. Ashurst LLP acts as legal adviser to the Joint Bookrunners as to US securities law.

The information was submitted for publication, through the agency of the contact person set out above, at 10:30 CEST on May 25, 2021.

About arfolitixorin

Arfolitixorin is Isofol’s proprietary drug candidate being developed to increase the efficacy of standard of care chemotherapy for advanced colorectal cancer. The drug candidate is currently being studied in a global Phase III study, AGENT. As the key active metabolite of the widely used folate-based drugs, arfolitixorin can potentially benefit more patients with advanced colorectal cancer, as it does not require complicated metabolic activation to become effective.

On May 25, 2021 TRACON Pharmaceuticals (NASDAQ: TCON), a clinical stage biopharmaceutical company focused on the development and commercialization of novel targeted cancer therapeutics and utilizing a cost efficient, CRO-independent product development platform to partner with ex-U.S. companies to develop and commercialize innovative products in the U.S., reported that Charles Theuer, M.D., Ph.D., President and Chief Executive Officer, will present a corporate overview at the Jefferies Virtual Healthcare Conference on June 4, 2021 at 2:30pm Eastern Time (Press release, Tracon Pharmaceuticals, MAY 25, 2021, View Source [SID1234580562]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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To access a live webcast of the presentation, please visit the "Events and Presentations" page within the "Investors" section of the TRACON Pharmaceuticals website at www.traconpharma.com.

On May 25, 2021 BioTheryX, Inc., a clinical-stage company focused on degrading proteins to create life-saving medicines, reported that the company will present virtually at the 2021 Jefferies Virtual Healthcare Conference on Tuesday, June 1st, 2021 at 1:30 pm ET (Press release, BioTheryX, MAY 25, 2021, View Source [SID1234580578]). A live webcast of the presentation can be accessed here and will be made available on the company’s website under the Events section.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Robert Williamson, President and CEO, will present an overview on the company’s targeted protein degradation platform, its clinical stage oncology pipeline, and the management team will participate with him in 1x1s with investors.

On May 25, 2021 Avid Bioservices, Inc. (NASDAQ:CDMO) (NASDAQ:CDMOP), a dedicated biologics contract development and manufacturing organization (CDMO) working to improve patient lives by providing high quality development and manufacturing services to biotechnology and pharmaceutical companies, reported that it will serve as the commercial manufacturer for the humanized monoclonal antibody portion of ZYNLONTA (loncastuximab tesirine-lpyl), a recently approved cancer treatment developed by ADC Therapeutics SA (NYSE: ADCT) (Press release, Avid Bioservices, MAY 25, 2021, View Source [SID1234580530]). Avid has provided clinical manufacturing services to ADC Therapeutics to support development of the product since 2017 and will now expand its manufacturing relationship with ADC Therapeutics to include commercial manufacturing activities for ZYNLONTA.

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ZYNLONTA is an antibody drug conjugate (ADC) composed of a humanized monoclonal antibody directed against human CD19 and conjugated through a linker to a pyrrolobenzodiazepine (PBD) dimer cytotoxin. In April 2021, ADC Therapeutics received U.S. Food and Drug Administration (FDA) approval for ZYNLONTA for the treatment of adult patients with relapsed or refractory (r/r) large B-cell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL) not otherwise specified (NOS), DLBCL arising from low-grade lymphoma and also high-grade B-cell lymphoma. As part of the ZYNLONTA approval process, Avid hosted the FDA earlier this year for the Pre-License Inspection (PLI), which was completed with no 483 observations.

"ADC Therapeutics is a highly valued client and we are pleased it has elected to expand the scope of our work to include commercial manufacturing of ZYNLONTA. We have worked closely with the company to provide clinical manufacturing services in support of this program as it advanced through clinical development and regulatory approval. Our experience with this innovative product, our strong relationship with the ADC team and exceptional quality systems will allow us to seamlessly transition efforts to producing commercial supply," said Timothy Compton, chief commercial officer of Avid. "Our experience with ADC Therapeutics provides an excellent case study in how Avid is well positioned to support the evolving needs of our clients as they advance innovative biologics through the clinical development and regulatory approval processes. Starting with early-stage clinical manufacturing and advancing into commercial supply production, Avid offers clients like ADC Therapeutics the opportunity to work with a single trusted partner throughout the development life cycle."

"We are delighted to expand our relationship with the team at Avid as they have significant experience producing monoclonal antibodies," said Mike Mulkerrin, VP, Head of Chemistry, Manufacturing and Control of ADC Therapeutics. "Avid has been a trusted and responsive manufacturing partner for the last four years and we look forward to collaborating with them in this next phase of our work to bring ZYNLONTA to more patients in need of a new therapeutic option."