ARTMS to Advance ImmunoPET Imaging Isotope with Funding Support from Innovate BC

On March 2, 2021 ARTMS Inc., the global leader in the development and commercialization of novel technologies and products enabling cyclotron production of the world’s most needed medical radioisotopes, reported that it received $300,000 funding from Innovate BC as part of its Ignite program (Press release, ARTMS Products, MAR 2, 2021, View Source [SID1234575964]). The funding will be combined with over $600,000 from additional sources to further develop and validate the production of zirconium-89 (Zr-89) ­for use in Positron Emission Tomography (PET) imaging scans of cancer patients eligible for immuno-oncology (IO) therapies.

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"While immuno-oncology therapy holds great promise for many cancer patients, the challenge is understanding which patients will benefit from a given therapeutic. The Ignite funding will help us advance the development of Zr-89, a leading medical isotope utilized in identifying potential IO responder patients."

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Mr. Raghwa Gopal, President/CEO of Innovate BC, commented about the work with ARTMS, "We’re excited to help accelerate game-changing innovation like ARTMS’ proprietary approach to producing critically important, high-quality radiopharmaceutical medical isotopes for cancer patients. Past winners have solved critical market problems that other companies have tried to solve for 50 years."

"We want to thank the Innovate BC team for their support and confidence in ARTMS," said Dr. Michael Cross, Chief Operating Officer and project lead at ARTMS. "While immuno-oncology therapy holds great promise for many cancer patients, the challenge is understanding which patients will benefit from a given therapeutic. The Ignite funding will help us advance the development of Zr-89, a leading medical isotope utilized in identifying potential IO responder patients."

The overarching goal of this project is to utilize ARTMS’ proprietary QUANTM Irradiation SystemTM (QISTM) hardware system and expertise in solid targetry to produce high-quality and high-activity Zr-89 for the radiolabeling of molecular targeting ligands, such as antibodies, which are used in the non-invasive monitoring of the immune system by Immuno-Positron Emission Tomography.

Dr. Paul Schaffer, Principal Investigator and Chief Technology Officer of ARTMS remarked, "The emergence of Immuno-PET using Zr-89-based radiopharmaceuticals as a companion diagnostic with immuno-therapy allows physicians to better understand their patient’s specific molecular signature and thereby enables a personalized medicine approach with their treatment."

With the goal of providing efficient and cost-effective radioisotope supply solutions, ARTMS continues to drive a paradigm shift in the practice of nuclear medicine by disrupting the current supply chain with its award-winning QIS hardware and consumable products.

Ad hoc: MorphoSys AG preliminary results for the fiscal year 2020 exceeding guidance

On March 2, 2021 MorphoSys AG (FSE: MOR; Prime Standard Segment; MDAX & TecDAX; NASDAQ: MOR) reported that according to the analysis of the preliminary results during the ongoing year end closing process, MorphoSys’ outlook has been exceeded (Press release, MorphoSys, MAR 2, 2021, View Source [SID1234575983]). Group revenues for 2020 are expected to amount to € 327.7 million and therefore slightly above the upper end of the guidance range from € 317 to 327 million. Group revenues include € 18.5 million (USD 22.0 million) revenues from product sales of Monjuvi as well as € 42.5 million for royalties on net sales of Tremfya. EBIT (Earnings before Interests and Taxes) for 2020 is expected to be € 27.4 million, and therefore significantly above the upper end of the guidance range of € 10 to 20 million. Expenses for research and development are expected to amount to € 141.4 million and therefore slightly above the guided range of € 130 to 140 million.

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All figures are preliminary. Full results will be published as planned on March 15, 2021.

Inhibikase Therapeutics to Present at H.C. Wainwright & Co. Global Life Sciences Virtual Conference

On March 2, 2021 Inhibikase Therapeutics, Inc. (NASDAQ: IKT) (Inhibikase), a clinical-stage pharmaceutical company developing therapeutics to modify the course of Parkinson’s disease and related disorders inside and outside of the brain, reported that Milton Werner, Ph.D., Chief Executive Officer of Inhibikase, will present at the H.C. Wainwright & Co. Global Life Sciences Virtual Conference (Press release, Inhibikase Therapeutics, MAR 2, 2021, https://www.inhibikase.com/news/press-releases/detail/29/inhibikase-therapeutics-to-present-at-h-c-wainwright-co [SID1234575917]).

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The presentation will be available for on-demand viewing under "News & Events" in the Investors section of the Company’s website at www.inhibikcase.com, beginning Tuesday, March 9th, 2021 at 7:00 am ET. The webcast will be available for approximately 90 days following the event.

Five Prime Therapeutics Announces Timing of Its Fourth Quarter 2020 and Full Year Results Conference Call

On March 2, 2021 Five Prime Therapeutics, Inc. (NASDAQ: FPRX), reported its fourth quarter and full year 2020 operational and financial results on Wednesday, March 10, 2021 after the U.S. financial markets close (Press release, Five Prime Therapeutics, MAR 2, 2021, View Source [SID1234575933]). Five Prime will also host a conference call and live audio webcast that same day at 4:30 p.m. (ET) / 1:30 p.m. (PT) to provide a general business update and discuss the company’s financial results.

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The live audio webcast may be accessed through the "Events & Presentations" page in the "Investors" section of the company’s website at www.fiveprime.com. Alternatively, participants may dial (877) 878-2269 (domestic) or (253) 237-1188 (international) and refer to conference ID: 9872966.

The archived conference call will be available on Five Prime’s website beginning approximately two hours after the event and will be archived and available for replay for at least 30 days after the event.

Navidea Biopharmaceuticals Announces $5 Million Private Placement with Existing Investor

On March 2, 2021 Navidea Biopharmaceuticals, Inc. (NYSE American: NAVB) ("Navidea" or the "Company"), a company focused on the development of precision immunodiagnostic agents and immunotherapeutics, reported that it has executed an agreement with the Company’s largest shareholder, John K. Scott, Jr., to purchase $5 million of newly-designated Series E Redeemable Convertible Preferred Stock (Press release, Navidea Biopharmaceuticals, MAR 2, 2021, View Source [SID1234575949]). Over the next 18 months, the Series E Preferred can be converted into approximately 2.17 million shares of Navidea’s common stock.

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"We are pleased to receive continued support from our largest shareholder. Today’s financing provides additional strength to our balance sheet and will allow our company to accelerate potential value-accretive investments, including our therapeutics pipeline," commented Jed Latkin, Chief Executive Officer of Navidea. "We look forward to providing additional updates on the progress of our ongoing studies across our portfolio on our earnings call later this month."

John K. Scott, Jr. commented, "I am pleased to be given the opportunity to continue to support Navidea as it moves some of its key assets into the next phase of development. As a stockholder in Navidea since December 2003, I believe in the Company’s drug candidates and the positive contributions they can make to individuals and the scientific community."

The securities offered and to be sold by Navidea in the private placement to Mr. Scott have not been registered under the Securities Act of 1933 (the "Securities Act"), as amended, or state securities laws and may not be offered or sold in the United States absent registration with the Securities and Exchange Commission (the "SEC") or an applicable exemption from registration requirements. Navidea has agreed to file a registration statement with the SEC covering the resale of the shares of common stock to be issued to Mr. Scott.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy any of Navidea’s securities. No offer, solicitation or sale will be made in any state or other jurisdiction in which such offering, solicitation or sale would be unlawful.