On October 11, 2022 NorthStar Medical Radioisotopes, LLC, a global innovator in the development, production and commercialization of radiopharmaceuticals used for therapeutic applications and medical imaging, and Eckert & Ziegler Isotope Technologies Dresden (ITD), a specialist for radiopharmaceutical plant engineering and fully owned subsidiary of Eckert & Ziegler AG (ISIN DE0005659700, SDAX), reported an agreement for the purchase of hot cells and related equipment for NorthStar’s dedicated non-carrier-added (n.c.a.) actinium-225 (Ac-225) production facility (Press release, NorthStar Medical Radiostopes, OCT 11, 2022, View Source [SID1234621916]). Hot cells are specially designed shielded enclosures that allow the safe handling of radioactive material. The equipment, worth several million USD, will be used by NorthStar in Beloit, Wisconsin, to produce commercial-scale quantities of n.c.a. Ac-225. Ac-225 is an emerging medical radioisotope for potential use in the treatment of cancer. The manufacturing process for these advanced radiopharmaceuticals requires innovative solutions and equipment to enable routine large-scale commercial production of Ac-225.
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"This agreement underlines our long-standing and extensive know-how in the construction of customized special plants, both because of its scope and with respect to the technological requirements," explained Felix Husmann, Managing Director of Eckert & Ziegler’s subsidiary Isotope Technologies Dresden GmbH. "We are proud that a leading radiopharmaceutical company like NorthStar is putting its trust in our expertise in process development."
"NorthStar is confident that we will be the first commercial-scale supplier of n.c.a. Ac-225 utilizing our environmentally preferable and non-uranium based electron accelerator technology," said Stephen Merrick, Chief Executive Officer of NorthStar Medical Radioisotopes. "From the preliminary stages of this project, we have had the full support of ITD’s technology team. We consider them the leading industry specialist in turnkey facilities for radiochemical and radiopharmaceutical processes, and anticipate that their technical solutions will enable us to make a significant contribution to the global supply of Ac-225 in the future."