Entry into a Material Definitive Agreement

On November 23, 2019, Adaptimmune Therapeutics plc (the "Company") reported that it has entered into Amendment No. 1 effective as of November 18, 2019 (the "Amendment") to the License Agreement and Sublicense Agreement effective as of December 19, 2012 (the "License Agreements") and the Commercial Development and Supply Agreement effective as of June 1, 2016 (the "Supply Agreement"), which the Company entered into with Life Technologies Corporation, an affiliate of Thermo Fisher Scientific Inc (Filing, 8-K, Adaptimmune, NOV 23, 2019, View Source [SID1234551693]). The Amendment changed the License Agreements from exclusive licensing agreements to a non-exclusive agreement. The Amendment also contained adjustments to the Company’s minimum purchase obligations under the Supply Agreement. The foregoing description of the Amendment is only a summary of the material terms thereof, and does not purport to be complete. The description is qualified in its entirety by reference to the Amendment, which will be filed as an exhibit to the Company’s Annual Report on Form 10-K for the year ended December 31, 2019.

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