On October 24, 2022 Adaptimmune Therapeutics plc ("Adaptimmune") reported to have received notice of termination of the Collaboration and License Agreement ("Collaboration Agreement") between Adaptimmune Limited and GlaxoSmithKline Intellectual Property Development Ltd ("GSK") dated May 30, 2014 (Press release, Adaptimmune, OCT 24, 2022, View Source [SID1234625433]). On December 19, 2022 and as a result of such termination, Adaptimmune and GSK entered into Amendment Agreement No. 8 (the "Amendment") further amending the Collaboration Agreement. The Amendment deleted Section 13.6.9 of the Collaboration Agreement relating to GSK’s post termination manufacturing and supply obligations in consideration for the payment of £5 million by GSK to Adaptimmune and clarified that no additional milestones are due under the Collaboration Agreement. The Amendment also clarified the allocation of responsibilities between GSK and Adaptimmune with respect to the transfer of information relating to the manufacturing process for the collaboration product targeting NY-ESO (lete-cel) and information relating to the collaboration program directed to the PRAME target to Adaptimmune. Further elements of the transfer of the NY-ESO and PRAME programs and any remaining payments are subject to further negotiation and a future agreement between the parties.

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