On February 22, 2019 Bexion Pharmaceuticals, Inc. (Bexion) reported the opening of Part 3 of their Phase I First-In-Human Trial using BXQ-350 for the treatment of cancer (Press release, Bexion, FEB 22, 2019, View Source [SID1234533802]). This trial was designed to determine the maximum tolerated dose of BXQ-350 and to characterize its safety and pharmacokinetics.

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The Phase I Part 1 study showed that BXQ-350 was well tolerated at all five doses tested with no dose limiting toxicities observed and with no serious adverse events attributed to the therapy. Part 2 tested the highest dose in an additional 36 solid tumor patients. Preliminary data support a safe and tolerable drug profile. The purpose of Part 3 will be to explore safety, and additional indications in rare and gastrointestinal tumors.

"By enrolling patients in Part 3, we hope to gain a better understanding of the potential of BXQ-350 in treating cancer," stated Dr. Ray Takigiku, Founder and CEO of Bexion.