Genomic Testing Cooperative (GTC) and C2i Genomics Announce Collaboration to Offer Liquid Biopsy Testing for Staging and Monitoring Solid Tumors Based on Pattern Recognition of Whole Genome DNA Signature

On January 14, 2020 Genomic Testing Cooperative, LCA (GTC), a cooperative (Co-Op) company offering comprehensive genomic profiling of hematologic and solid tumors, and C2i Genomics, Inc, a tumor pattern recognition liquid biopsy company, reported collaboration to develop liquid biopsy tests for the staging and monitoring of solid tumors (Press release, Genomic Testing Cooperative, JAN 14, 2020, View Source [SID1234553208]). C2i Genomics approach is based on proprietary technology using AI-based pattern recognition of whole genome sequencing of cell-free DNA (cfDNA). The technology will be adapted by GTC and distributed to the Co-Op members upon completion of technical and clinical validation. This technology will be used for highly accurate personalized monitoring of patients with various types of cancer. The initial focus of this collaboration will be on cancers of the lung, colon, breast, and melanoma.

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Dr. Asaf Zviran, C2i Genomics Chief Executive Officer and Chief Scientific Officer stated, "We are delighted to be working with GTC to transition our technology from the research and development phase into a real-world clinical diagnostic test. Using our liquid biopsy approach to more sensitively and accurately stage and monitor patients with early stage cancer addresses an unmet need and we believe that the extensive experience of the team at GTC in developing and validating new clinically actionable tests will significantly accelerate bringing this innovation to patient care."

Dr. Maher Albitar, GTC Chief Executive Officer and Chief Medical Officer, said, "We believe that broad whole genome pattern recognition of genomic abnormalities is a reliable approach for cancer patients staging and monitoring. Working on the clinical development of this type of testing with C2i Genomics is aligned with GTC’s mission as an innovation company focused on expanding the use of genomics in improving patient care."

As part of the agreement, GTC will perform sequencing and participate in the efforts of technical and clinical validation. C2i will be responsible for the AI-based analysis of data, recruitment of samples and various clinical trial activities.