On November 29, 2022 Helsinn Group ("Helsinn"), a fully integrated global biopharma company with a track record of over forty years of commercial execution and a strong focus in oncology and rare diseases announces, announces its poster presentation at the upcoming European Society for Medical Oncology (ESMO) (Free ESMO Whitepaper) Asia Congress, being held in Singapore from 2-4 December(Press release, Helsinn, NOV 29, 2022, View Source [SID1234624536]).
Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:
Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing
Schedule Your 30 min Free Demo!
Helsinn will be presenting a poster on the ongoing MyRisk international trial, assessing whether the administration of a combined treatment of NEPA (Fixed Combination of Netupitant/Palonosetron) and dexamethasone is more effective than the current standard of care prophylaxis1-2-3 (a combination of 5-HT3 receptor antagonist and dexamethasone) in preventing Chemotherapy-induced Nausea and Vomiting (CINV) in patients at increased risk of emesis receiving moderately emetogenic chemotherapy.
Full details of the poster presentation are below:
Title: Assessing the Benefit of NEPA (Fixed Combination of Netupitant/Palonosetron) for Preventing Chemotherapy-induced Nausea and Vomiting (CINV) in Patients at Increased Emetic Risk Receiving Moderately Emetogenic Chemotherapy
Author: Alex Molassiotis, Matti Aapro, Alessandro Alonzi, Marika Chrápavá, Karin Jordan Eric J. Roeland, Lee Schwartzberg, Carole Terrasanta, Silvia Olivari Tilola, George Dranitsaris
Session: Poster session, 03 December, 18:00 – 18:45
Abstract ID: NCT04817189
Dr Silvia Sebastiani, Helsinn Group Head of Medical Affairs, commented: "We are pleased to present the design of this important ongoing study at the ESMO (Free ESMO Whitepaper) Asia congress. Despite the array of effective antiemetics, CINV still represents a huge unmet need in clinical practice. To further the goal of CINV prevention for all patients undergoing emetogenic chemotherapy, it is important to explore ways to optimize antiemetic selection, including exploring factors that may increase CINV risk for patients."
Prof. Alex Molassiotis, Pro Vice Chancellor and Dean, University of Derby, UK and Scientific Lead of the MyRisk study added: "In patients receiving moderately emetogenic chemotherapy (MEC), antiemetic guidelines generally recommend a setron + dexamethasone (DEX). However, one guideline committee (the National Comprehensive Cancer Network ("NCCN")) recognized that this approach is inadequate prophylaxis for many patients and included an NK1 RA-containing option selectively for those with individual emetic risk factors2. MyRisk is the first study prospectively exploring the role of NK1 RA-containing regimen, Akynzeo in this case, in patients receiving MEC who have additional risk factors."