On November 05, 2015 Idera Pharmaceuticals, Inc. (NASDAQ:IDRA), a clinical-stage biopharmaceutical company developing toll-like receptor and RNA therapeutics for patients with cancer and rare diseases, reported that new data from the Phase 1/2 clinical trial for IMO-8400, a TLR 7,8 and 9 antagonist, being evaluated for the treatment of relapsed, refractory patients suffering from Waldenström’s Macroglobulinemia, will be presented at the 2015 American Society of Hematology (ASH) (Free ASH Whitepaper) Annual Meeting in Orlando, FL, December 5-8, 2015 (Press release, Idera Pharmaceuticals, NOV 5, 2015, View Source;p=RssLanding&cat=news&id=2107366 [SID:1234508011]).

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The open-label, dose-ranging clinical trial included three dose-escalating cohorts on IMO-8400 and enrolled 19 patients, who were relapsed or refractory to prior therapies. Data from these 19 patients will be presented at the ASH (Free ASH Whitepaper) Meeting.

"The presentation of the clinical safety and efficacy data from our IMO-8400 study in Waldenström’s Macroglobulinemia is a positive step forward for our company, for our clinical aspirations in cancer care and for the role of Toll-Like Receptors as a therapeutic option for patients suffering from B-cell Lymphomas," stated Vincent Milano, Idera’s Chief Executive Officer. "We look forward to presenting the data next month at the ASH (Free ASH Whitepaper) conference and beginning to elucidate the path forward for IMO-8400 beyond this first clinical study."

Poster Presentation

Date: Saturday, December 5, 2015, Presentation Time: 5:30 PM ET – 7:30 PM ET
Session Title: 624. Lymphoma: Therapy with Biologic Agents, excluding Pre-Clinical Models: Poster I
Publication Number: 1540
Presentation Title: Preliminary Results from a Phase 1/2 Open-Label, Dose-Escalation Clinical Trial of IMO-8400 in Patients with Relapsed or Refractory Waldenström’s Macrogloblulinemia
Location: Orange County Convention Center, Hall A