Juno Therapeutics to Resume JCAR015 Phase II ROCKET Trial

On July 12, 2016 Juno Therapeutics, Inc. (Nasdaq: JUNO), a biopharmaceutical company focused on re-engaging the body’s immune system to revolutionize the treatment of cancer, reported that the U.S. Food and Drug Administration has removed the clinical hold on the Phase II clinical trial of JCAR015 (known as the "ROCKET" trial) in adult patients with relapsed or refractory B cell acute lymphoblastic leukemia (r/r ALL) (Press release, Juno, JUL 12, 2016, View Source [SID:1234513848]).

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Under the revised protocol, the ROCKET trial will continue enrollment using JCAR015 with cyclophosphamide pre-conditioning only.