On March 14, 2023 Kura Oncology, Inc. (Nasdaq: KURA), a clinical-stage biopharmaceutical company committed to realizing the promise of precision medicines for the treatment of cancer, reported that two abstracts have been accepted for presentation at the upcoming American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting, to be held in Orlando from April 14-19, 2023 (Press release, Kura Oncology, MAR 14, 2023, View Source [SID1234628701]).

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"We look forward to presenting preclinical data supporting the combination of farnesyl transferase inhibitors (FTIs) with KRASG12C inhibitors and tyrosine kinase inhibitors at this year’s AACR (Free AACR Whitepaper) Annual Meeting," said Troy Wilson, Ph.D., J.D., President and Chief Executive Officer of Kura Oncology. "These data add to the emerging body of evidence supporting the potential to use FTIs as combination agents to prevent or delay emergence of resistance to certain classes of targeted therapy. We recently announced FDA clearance of the Investigational New Drug application for our next-generation farnesyl transferase inhibitor, KO-2806, which was designed to improve upon potency, pharmacokinetic and physicochemical properties of earlier FTI drug candidates, and we look forward to initiating our FIT-001 Phase 1 trial with KO-2806 later this year."

Session titles and information for the two abstracts are listed below and are now available on the AACR (Free AACR Whitepaper) online itinerary planner.

Combination of tipifarnib with KRASG12C inhibitors to prevent adaptive resistance 
Session Category / Title: Clinical Research Excluding Trials / Precision Molecular Subtyping and Therapeutic Development
Session Date and Time: Sunday, April 16, 2023; 1:30 PM – 5:00 PM ET
Location: Orange County Convention Center, Poster Section 43
Abstract / Poster: 1079 / 23

Tipifarnib synergizes with TKIs in clear cell renal cell carcinoma models
Session Category / Title: Clinical Research Excluding Trials / Precision Molecular Subtyping and Therapeutic Development
Session Date and Time: Sunday, April 16, 2023; 1:30 PM – 5:00 PM ET
Location: Orange County Convention Center, Poster Section 43
Abstract / Poster: 1071 / 15

Copies of the presentations will be available on Kura’s website at View Source following presentation at the meeting.