On October 16, 2017 Kura Oncology, Inc. (Nasdaq:KURA), a clinical stage biopharmaceutical company focused on the development of precision medicines for oncology, reported presentations at the AACR (Free AACR Whitepaper)-NCI-EORTC AACR-NCI-EORTC (Free AACR-NCI-EORTC Whitepaper) International Conference on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR) (Free ASGCT Whitepaper) (Free EORTC-NCI-AACR Whitepaper), taking place October 26-30, 2017 in Philadelphia (Press release, Kura Oncology, OCT 16, 2017, View Source;p=RssLanding&cat=news&id=2308717 [SID1234520946]).
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A late-breaking poster will be presented on Saturday, October 28, by Dr. Alan Ho of Memorial Sloan Kettering Cancer Center and will feature data from Kura’s recently-announced positive Phase 2 proof-of-concept trial in head and neck squamous cell carcinoma (HNSCC) with HRAS mutations. In addition, the poster has been selected as the subject of a short, oral presentation during the Spotlight on Proffered Papers Session 1 on Friday, October 27.
A second late-breaking poster will be presented on Saturday, October 28, and will feature preclinical data for KO-539, Kura’s potent and selective inhibitor of the menin-MLL interaction, supporting the potential clinical utility of KO-539 in NPM1- and DNMT3A-mutant AML.
The schedule and locations for the late-breaking oral presentation and poster presentations is as follows:
Oral Presentation:
Title of Presentation: Preliminary results from a Phase 2 proof-of-concept trial of tipifarnib in tumors with HRAS mutations
Date & Time: Friday, October 27, 2017, 10:50 a.m. – 12:20 p.m. EDT
Presenter: Alan L. Ho, M.D., Ph.D., Memorial Sloan Kettering Cancer Center
Session: Spotlight on Proffered Papers Session 1
Location: Terrace Ballroom, 400 Level, Pennsylvania Convention Center
Poster Presentations:
Title of Poster: Preliminary results from a Phase 2 proof-of-concept trial of tipifarnib in tumors with HRAS mutations
Date & Time: Saturday, October 28, 12:30 p.m. – 4:00 p.m. EDT
Presenter: Alan L. Ho, M.D., Ph.D., Memorial Sloan Kettering Cancer Center
Session: Late-Breaking Poster Session A (Clinical Trials)
Abstract Number: LB-A10
Location: Hall E, Pennsylvania Convention Center
Title of Poster: A novel small molecule menin-MLL inhibitor for potential treatment of MLL-rearranged leukemias and NPM1/DNMT3A-mutant AML
Date & Time: Saturday, October 28, 12:30 p.m. – 4:00 p.m. EDT
Presenter: Francis Burrows, Ph.D., Kura Oncology
Late-Breaking Poster Session A (Epigenetic Targets)
Abstract Number: LB-A27
Location: Hall E, Pennsylvania Convention Center