On February 23, 2022 NanoString Technologies, Inc. (NASDAQ: NSTG), a leading provider of life science tools for discovery and translational research, reported the release of a fully automated GeoMx RNA protocol on BOND RX research staining systems through an expanded partnership with Leica Biosystems (Press release, NanoString Technologies, FEB 23, 2022, View Source [SID1234608904]). The new, improved RNA protocol offers whole transcriptome profiling of Formalin-Fixed Paraffin-Embedded (FFPE), fixed frozen, or fresh frozen tissue, ultimately improving reproducibility and throughput, minimizing manual steps, and reducing hands-on time.
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"This fully automated protocol not only increased our ability to get more slides done in a week but also increased the quality of the data coming off of our instrument by reducing variability between runs," said Carlee Hemphill, formerly a lead scientist with Labcorp, a beta site for the automated workflow, now senior manager, Translational and R&D Services, PathAI.
The GeoMx Digital Spatial Profiler (DSP) combines standard immunofluorescence techniques with digital barcoding technology to perform highly multiplexed, spatially resolved multi-omic profiling studies. The BOND RX staining solution offers investigators an open platform to develop customized protocols for immunohistochemistry (IHC) and In Situ Hybridization (ISH) with open reagents and detection options. The new protocol creates a fully automated GeoMx DSP workflow allowing researchers to quickly see the biological complexity of heterogeneous tissues using GeoMx DSP’s combination of tissue morphological context and high-plex, whole transcriptome RNA expression profiling from a single slide.
"We’re excited to have the Leica workflow as part of our spatial biology ecosystem," said Vice President of Marketing for NanoString, Anna Berdine. "Enabling full automation facilitates translational and multi-sample studies by improving reproducibility and decreasing the hands-on time down to less than one hour, freeing up researchers to focus more of their time on generating insights from their data."
To learn more about NanoString’s GeoMx Digital Spatial Profiler, visit View Source