On June 18, 2025 Neogap Therapeutics, a Swedish clinical-stage biotechnology company developing personalised immunotherapy for cancer, reported it will participate in this year’s Neoantigen Summit Europe in Amsterdam (Press release, Neogap Therapeutics, JUN 18, 2025, View Source,c4165752 [SID1234653978]). Ola Nilsson, Head of Neoantigen Production, Development & Clinical Processing at Neogap, is an invited expert speaker and will present the company’s personalised cell therapy pTTL and its EpiTCer technology.
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pTTL (personalised tumour-trained lymphocytes) is a personalised cell therapy based on the patient’s own T cells, extracted from regional lymph nodes and trained to recognise tumour-specific neoantigens. The treatment is currently being evaluated in an ongoing Phase I/IIa clinical trial in patients with advanced colorectal cancer.
EpiTCer, Neogap’s proprietary technology, plays a central role in the development of pTTL. By mimicking natural antigen presentation, it delivers selected neoantigens to the immune system. It is also used to develop potency assays – functional tests that assess the therapy’s ability to trigger a tumour-directed immune response.
"The EpiTCer technology is very powerful, as it not only enables efficient delivery of neoantigens to the immune system and selective expansion of tumour-specific T cells, but also provides us with the tools to functionally assess the potency of our therapy. This combination makes Neogap’s approach unique within cell therapy," says Ola Nilsson, Head of Neoantigen Production, Development & Clinical Processing at Neogap Therapeutics.
"Neoantigen Summit is a key international forum for demonstrating how we bridge technological innovation with clinical application – and to contribute our perspectives to the global conversation on the future of cancer treatment."
Neoantigen Summit Europe is a leading international conference focused on neoantigen-based therapies, bringing together researchers, clinicians and industry leaders from around the world.
The conference will be held in Amsterdam on 24–26 June 2025. Ola Nilsson is scheduled to speak on 26 June at 11:30. For registration and program details, visit the event website: https://neoantigen-summit.com/.