Helix BioPharma Corp. Closes Private Placement

On December 30, 2020 Helix BioPharma Corp. (TSX: "HBP") ("Helix" or the "Company"), a clinical-stage biopharmaceutical company developing unique therapies in the field of immuno-oncology, based on its proprietary technological platform DOS47, reported it has closed a private placement financing for gross proceeds of $3,000,000 (Press release, Helix BioPharma, DEC 30, 2020, View Source [SID1234573344]).

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The terms of the placement are for the purchase of units at $0.50 per unit. Each unit is comprised of one common share and one common share purchase warrant. Each common share purchase warrant will entitle the holder to purchase one common share at an exercise price of $0.70 and have an expiry of five years from the date of issuance. Helix intends to use the net proceeds of the private placement for working capital and research and development activities.

ACM Alpha Consulting Management AG provided financial advisory services to Helix in connection with the private placement.

Ascentage Pharma Officially Included in Shenzhen-Hong Kong Stock Connect Program

On December 30, 2020 Ascentage Pharma (6855.HK), a globally focused, clinical-stage biotechnology company engaged in developing novel therapies for cancers, chronic hepatitis B (CHB), and age-related diseases, reported that the company was officially included into the Shenzhen-Hong Kong Stock Connect program (the "Hong Kong Stock Connect") (Press release, Ascentage Pharma, DEC 30, 2020, View Source [SID1234573343]). This was officially announced by the Shenzhen Stock Exchange ("SZSE") on December 25, 2020, which has been effective since December 28, 2020. This inclusion is the very first arrangement for the eligible pre-revenue biotech companies listed under Chapter 18A of Hong Kong’s Main Board Listing Rules, and complied with the conditions for the inclusion in the Hong Kong Stock Connect.

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The Hong Kong Stock Connect is a collaboration program between the Hong Kong, Shanghai and Shenzhen Stock Exchanges. Stock Connect allows international and China Mainland investors to trade securities in each other’s markets through the trading and clearing platforms of their home exchange. In this adjustment, a total of six eligible pre-revenue biotech companies will be the first included in the Hong Kong Stock Connect. The expansion of the eligible stocks of Hong Kong Stock Connect, will further optimize the interconnected, intercommunicated, and mutual development of the capital markets between Mainland China and Hong Kong.

As the first biotech stock specializing in small molecular innovative drugs, Ascentage Pharma has made significant progress in clinical development, external partnership, and patent distribution during the recent one year since its listing, and achieved a number of global collaborations, which is transforming the company from an R&D enterprise for self-innovative new drug to an R&D and manufacturing enterprise. In 2020, Ascentage Pharma made its first New Drug Application (NDA) and was granted priority review by China National Medical Products Administration (NMPA), achieving a significant milestone. During the past six months, the company has kept ahead in the industry, four new drugs have been granted eight Orphan Drug Designation (ODD) by the US Food and Drug Administration (FDA). In August, Ascentage Pharma was included in the Hang Seng Composite Index, the Hang Seng Hong Kong-Listed Biotech Index and the Hang Seng Healthcare Index, which have become effective in September 2020. Only over a year since the listing, Ascentage Pharma was included in the Hang Seng Index as well as the Hong Kong Stock Connect, fully demonstrating that its value for investment and the future prospect are highly recognized in the capital market.

"As one of the first batch of the arranged Chapter 18A companies according to the new regulation, the inclusion of the company is a significant milestone and fully reflects the recognition and confidence in the company’s business and development prospects from the capital market, and will facilitate further expansion of our investor base and enhance the liquidity of our stocks," said Dr. Dajun Yang, Chairman & CEO of Ascentage Pharma. "In the future, we will adhere to the innovation strategy and continue strengthening the R&D, and maintaining our leading position in the industry in order to accelerate the global clinical development of our pipelines, We will commit to Ascentage Pharma’s mission of ‘addressing the unmet clinical needs in China and around the world’, benefitting worldwide patients and return to our public shareholders and investors."

Thermo Fisher Scientific Announces Redemption of Senior Notes

On December 30, 2020 Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science, reported that on December 31, 2020, it will give notice of its intention to redeem the following Senior Notes, representing an aggregate total principal amount of approximately $2.6 billion, on January 15, 2021 (the "Redemption Date") (Press release, Thermo Fisher Scientific, DEC 30, 2020, View Source [SID1234573342]):

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€0.5 billion aggregate principal amount of 2.150% Senior Notes due 2022 (NYSE: TMO 22A) (the "2022 Notes")
$1.0 billion aggregate principal amount of 3.000% Senior Notes due 2023 (the "2023 Notes")
$1.0 billion aggregate principal amount of 4.150% Senior Notes due 2024 (the "2024 Notes" and, together with the 2022 Notes and the 2023 Notes, the "Notes")
The Notes will be redeemed at a redemption price equal to the greater of (1) 100% of the principal amount of the Notes to be redeemed and (2) the sum of the present values of the remaining scheduled payments of the Notes to be redeemed discounted to the Redemption Date (a) on an annual basis at a comparable bond rate plus 25 basis points in the case of the 2022 Notes, (b) on a semi-annual basis at a comparable treasury rate plus 25 basis points in the case of the 2023 Notes and (c) on a semi-annual basis at a comparable treasury rate plus 20 basis points in the case of the 2024 Notes, plus, in each case, accrued and unpaid interest on the Notes to be redeemed to, but excluding, the Redemption Date. Thermo Fisher intends to fund the redemption using cash on hand.

ImmunoGen Announces Webcast of Presentation and Q&A at the 39th Annual J.P. Morgan Healthcare Conference

On December 30, 2020 ImmunoGen Inc. (Nasdaq: IMGN), a leader in the expanding field of antibody-drug conjugates (ADCs) for the treatment of cancer, reported that Mark Enyedy, President and CEO, will present at the upcoming 39th Annual J.P. Morgan Virtual Healthcare Conference. The presentation is scheduled for 10:50am ET on January 13, 2021 (Press release, ImmunoGen, DEC 30, 2020, View Source [SID1234573341]).

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Following the presentation, Mr. Enyedy will be joined by other members of ImmunoGen’s management team for a question-and-answer session at 11:10am ET.

A webcast of the presentation and question-and-answer session will be accessible live through the "Investors & Media" section of the Company’s website, www.immunogen.com; a replay will be available in the same location.

Guardant Health to Participate in the 39th Annual J.P. Morgan Healthcare Conference

On December 30, 2020 Guardant Health, Inc. (Nasdaq: GH), a leading precision oncology company, reported the company will be participating in the upcoming 39th Annual J.P. Morgan Virtual Healthcare Conference (Press release, Guardant Health, DEC 30, 2020, View Source [SID1234573340]).

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Guardant Health’s management is scheduled to present on Monday, January 11 at 7:50 a.m. Pacific Time / 10:50 a.m. Eastern Time. Interested parties may access a live and archived webcast of the presentation on the "Investors" section of the company website at: www.guardanthealth.com.