AETERNA ZENTARIS ANNOUNCES $4.5 MILLION REGISTERED DIRECT OFFERING PRICED AT-THE-MARKET

On February 19, 2020 Aeterna Zentaris Inc. (NASDAQ: AEZS) (TSX: AEZS) ("Aeterna" or the "Company"), a specialty biopharmaceutical company commercializing and developing therapeutics and diagnostic tests, reported that it has entered into a securities purchase agreement with several institutional investors in the United States providing for the sale and issuance of approximately 3,478,261 common shares at a purchase price of $1.29375 per common share in a registered direct offering priced at-the-market under Nasdaq rules (Press release, AEterna Zentaris, FEB 19, 2020, View Source [SID1234554539]). The offering is expected to result in gross proceeds to Aeterna Zentaris of approximately $4.5 million.

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Aeterna Zentaris will also issue to the purchasers unregistered warrants to purchase up to an aggregate of 2,608,696 common shares. The warrants will be exercisable for a period of five and one-half years, exercisable immediately following the issuance date and have an exercise price of $1.20 per common share.

H.C. Wainwright & Co. is acting as the exclusive placement agent for the offering.

The registered direct offering and concurrent private placement is expected to close on or about February 21, 2020, subject to the satisfaction of customary closing conditions.

The common shares described above (but not the warrants or the common shares underlying the warrants) are being offered by Aeterna Zentaris pursuant to a "shelf" registration statement on Form F-3 (File No. 333-232935), which was previously declared effective by the U.S. Securities and Exchange Commission ("SEC") on August 15, 2019. Such common shares may be offered only by means of a prospectus, including a prospectus supplement, forming a part of the effective registration statement.

A prospectus supplement relating to the common shares will be filed by Aeterna with the SEC. When filed with the SEC, copies of the prospectus supplement and the accompanying prospectus relating to the registered direct offering, may be obtained at the SEC’s website at www.sec.gov. Electronic copies of the prospectus supplement and accompanying prospectus relating to the registered direct offering may also be obtained by contacting H.C. Wainwright & Co., LLC, 430 Park Avenue, 3rd Floor, New York, NY 10022, by telephone at (646) 975-6996 or by email at [email protected].

The warrants described above were offered in a private placement pursuant to an exemption from the Securities Act of 1933, as amended (the "Act"), and along with the common shares issuable upon their exercise, have not been registered under the Act, and may not be offered or sold in the United States absent registration with the SEC or an applicable exemption from such registration requirements.

This press release does not constitute an offer to sell or the solicitation of an offer to buy, nor will there be any sales of these securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such jurisdiction. No Canadian prospectus has been or will be filed in a province or territory of Canada to qualify the common shares or the warrants in connection with the offering.

NeuroVive Pharmaceutical AB Year End Report January – December 2019

On February 19, 2020 NeuroVive Pharmaceutical AB reported that Year End Report January – December 2019 (Press release, NeuroVive Pharmaceutical, FEB 19, 2020, View Source;december-2019-301007315.html [SID1234554533])

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Important events in 2019

KL1333

NeuroVive enrolls first subject in its European KL1333 phase Ia/b clinical study
NeuroVive initiates second part of its ongoing KL1333 Phase Ia/b clinical study
NeuroVive completes recruitment of healthy volunteers in the second part of its ongoing KL1333 clinical Phase Ia/b study
NV354

NeuroVive initiates NV354 preclinical safety studies and scales up compound production
NeuroSTAT

NeuroVive’s IND for clinical development of NeuroSTAT approved by FDA
NeuroSTAT receives Fast Track designation from the US Food and Drug Administration
Financials

NeuroVive is supplied with approximately MSEK 99.0 in share issue proceeds
NeuroVive receives SEK 28.2 Million in a directed new share issue
Strategy and communications

NeuroVive updates its strategy and sharpens its focus on primary mitochondrial diseases
NeuroVive hosts the company’s first Capital Markets Day
NeuroVive hosts the Mitochondria Day for the second time
Other

NeuroVive announces settlement in dispute with CicloMulsion AG
Important events after the reporting period

NeuroVive proposes a rights issue of approximately MSEK 74 before issue costs. The rights issue is guaranteed to 90%.
Financial information fourth quarter (Oct-Dec 2019)*

Net revenues: KSEK 49 (5)
Other operating income: KSEK 1,000 (1,009)
Loss before tax: KSEK 27,112 (19,978)
Loss per share: SEK -0.15 (-0.25)
Diluted loss per share: SEK -0.15 (-0.25)
Financial information full year 2019 (Jan-Dec 2019)*

Net revenues: KSEK 34 (5)
Other operating income: KSEK 3,500 (2,461)
Loss before tax: KSEK 77,000 (73,494)
Loss per share: SEK 0.45 (0.94)
Diluted loss per share: SEK 0.45 (0.94)
* APM Alternative perfomance measures, see definition on page 17 in the Report.

The complete Year End report is available for download below and through NeuroVive’s web site www.neurovive.com.

The information was submitted for publication, through the agency of the contact person set out below at 08:40 a.m. CET on 19 February 2020.

United Therapeutics Corporation to Report Fourth Quarter and Full Year 2019 Financial Results Before the Market Opens on Wednesday, February 26, 2020

On February 19, 2020 United Therapeutics Corporation (Nasdaq: UTHR) reported that it will report its fourth quarter and full year 2019 financial results before the market opens on Wednesday, February 26, 2020 (Press release, United Therapeutics, FEB 19, 2020, View Source [SID1234554531]).

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United Therapeutics will host a teleconference on Wednesday, February 26, 2020, at 9:00 a.m. Eastern Time. The teleconference is accessible by dialing (866) 209-9943 in the United States, with international callers dialing +1 (825) 312-2282. A rebroadcast of the teleconference will be available for one week and can be accessed by dialing (800) 585-8367 in the United States, with international callers dialing +1 (416) 621-4642, and using access code: 1598163.

This teleconference is also being webcast and can be accessed via United Therapeutics’ website at View Source

Caris Life Sciences to Present at Cowen and Company 40th Annual Health Care Conference

On February 19, 2020 Caris Life Sciences, a leading innovator in molecular science focused on fulfilling the promise of precision medicine, reported that Brian Brille, Vice Chairman of the Company, will present at the Cowen and Company 40th Annual Health Care Conference on Tuesday, March 3, 2020, at 9:30 a.m. Eastern time (Press release, Caris Life Sciences, FEB 19, 2020, https://www.prnewswire.com/news-releases/caris-life-sciences-to-present-at-cowen-and-company-40th-annual-health-care-conference-301007123.html [SID1234554530]). The conference is being held at the Boston Marriott Copley Place, Boston.

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Mr. Brille will provide an overview of the business and discuss recent corporate achievements that position Caris to further extend its leadership in the precision medicine market. He also will take questions from the audience.

Investors attending the conference who would like to schedule a one-on-one meeting with Caris executives may do so by contacting their Cowen representative.

Ionis Pharmaceuticals to hold 2019 financial results webcast

On February 19, 2020 Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) reported that it will host a live webcast on Wednesday, February 26th at 11:30 a.m. Eastern Time to discuss its 2019 financial results and report on pipeline and business progress (Press release, Ionis Pharmaceuticals, FEB 19, 2020, View Source [SID1234554529]).

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Click here to access the audio webcast and slides. A webcast replay will remain posted on Ionis’ website for a limited time.