CYCLACEL ANNOUNCES PRICING OF $20 MILLION PUBLIC OFFERING

On April 21, 2020 Cyclacel Pharmaceuticals, Inc. (NASDAQ: CYCC, NASDAQ: CYCCP; "Cyclacel" or the "Company"), a biopharmaceutical company developing innovative medicines based on cancer cell biology, reported the pricing of a public offering with expected total gross proceeds of approximately $20 million, before deducting placement agent fees and other offering expenses payable by the Company (Press release, Cyclacel, APR 21, 2020, View Source [SID1234556584]).

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Roth Capital Partners is acting as the lead placement agent for the offering. Ladenburg Thalmann and Brookline Capital Markets, a division of Arcadia Securities, LLC are acting as co-placement agents for the offering.

The securities offered by the Company consist of (i) 4,000,000 shares of its common stock (or pre-funded warrants to purchase common stock in lieu thereof) and (ii) common warrants to purchase up to 4,000,000 shares of common stock. Each share of common stock and, as applicable, each pre-funded warrant, is being sold together with a common warrant to purchase one share of common stock at a combined effective price to the public of $5.00 per share and accompanying common warrant, and/or $4.999 per pre-funded warrant and accompanying common warrant. For each pre-funded warrant the Company sells, the number of shares of common stock the Company is offering will be decreased on a one-for-one basis. The common warrants will be immediately exercisable at a price of $5.00 per share of common stock and will expire five years from the date of issuance. The shares of common stock and/or the pre-funded warrants, and the accompanying common warrants, can only be purchased together in the offering but will be issued separately and will be immediately separable upon issuance. The offering is expected to close on April 23, 2020, subject to customary closing conditions.

A registration statement relating to these securities has been filed with the Securities and Exchange Commission (the "SEC") and was declared effective on April 20, 2020. A final prospectus relating to the offering will be filed with the SEC and will be available on the SEC’s web site at www.sec.gov. Copies of the final prospectus relating to this offering may be obtained, when available, by contacting Roth Capital Partners, LLC, Attention: Equity Capital Markets, 888 San Clemente Drive, Suite 400, Newport Beach, California 92660, by telephone at (800) 678-9147 or e-mail at [email protected].

This press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

Myovant Sciences to Host Webcast and Conference Call at 8:30 a.m. Eastern Time Wednesday, April 22 to Discuss Results from Phase 3 SPIRIT 2 Study Evaluating Once-Daily Relugolix Combination Therapy in Women with Endometriosis and from Ovulation Inhibition

On April 21, 2020 Myovant Sciences (NYSE: MYOV), a healthcare company focused on redefining care for women’s health and prostate cancer, reported it will hold a webcast and conference call beginning at 8:30 a.m. Eastern Time / 5:30 a.m. Pacific Time on Wednesday, April 22, 2020, to discuss results from the Phase 3 SPIRIT 2 study of once-daily relugolix combination therapy (relugolix 40 mg plus estradiol 1.0 mg, and norethindrone acetate 0.5 mg) in women with pain associated with endometriosis (Press release, Myovant Sciences, APR 21, 2020, https://investors.myovant.com/news-releases/news-release-details/myovant-sciences-host-webcast-and-conference-call-830-am-2 [SID1234556503]). The company will also discuss results from a separate ovulation inhibition study with relugolix combination therapy.

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Webcast/Teleconference Details
To participate in the live conference call, please dial 1-800-532-3746 for domestic callers and +1-470-495-9166 for international callers. A live webcast of the conference call will also be available on the investor relations page of Myovant’s website at investors.myovant.com and will remain archived on Myovant’s website for at least 30 days.

Actinium Pharmaceuticals, Inc. Announces Proposed Public Offering

On April 21, 2020 Actinium Pharmaceuticals, Inc. (NYSE AMERICAN: ATNM) ("Actinium" or "the Company") reported that it intends to offer and sell shares of its common stock (or pre-funded warrants to purchase common stock in lieu thereof) in an underwritten public offering (Press release, Actinium Pharmaceuticals, APR 21, 2020, View Source [SID1234556502]). The Company expects to grant the underwriter a 30-day option to purchase up to an additional 15% of the number of the securities to be sold in the offering at the public offering price, less underwriting discounts and commissions. The offering is subject to market and other conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

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H.C. Wainwright & Co. is acting as the sole book-running manager for the offering.

Actinium intends to use the net proceeds from the offering to complete its ongoing pivotal, Phase 3 SIERRA trial for its lead product candidate, Iomab-B, and progress Phase 1 trials from its refocused CD33 program to the proof of concept stage. Net proceeds from this offering will also be used to support its AWE Technology Platform, Iomab-ACT program, research and development and general working capital needs.

A shelf registration statement on Form S-3 relating to the public offering of the shares of common stock described above was filed with the Securities and Exchange Commission ("SEC") and was declared effective on October 24, 2017. The offering will be made only by means of a written prospectus and prospectus supplement that form a part of the registration statement. A preliminary prospectus supplement describing the terms of the offering will be filed with the SEC. Electronic copies of the preliminary prospectus supplement and the accompanying base prospectus relating to the offering may be obtained, when available, from H.C. Wainwright & Co., LLC, 430 Park Avenue 3rd Floor, New York, NY 10022, or by calling (646) 975-6996 or by emailing [email protected] or at the SEC’s website at View Source

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

New Horizon Health Raises $20 Million for China Early-Stage Cancer Tests

On April 21, 2020 Omniscience reported that New Horizon Health of Hangzhou completed a $20 million Series D financing to support its early-stage cancer screening products (Press release, Omniscience, APR 21, 2020, View Source [SID1234556486]). Founded in 2013, New Horizon has launched at-home cancer screening products for colorectal cancer, cervical cancer, gastric cancer and lung cancer. The company claims to have served more than three million customers. New Horizon plans to use the funds to develop new products, make a large-scale investment in clinical research and upgrade its service system. The round was led by Omniscience, a private equity fund.

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Entopsis Selects Genetics Institute of America As Commercialization Partner for Prostate Cancer Test

On April 21, 2020 Entopsis, LLC reported that it has entered into a diagnostics commercialization agreement with Genetics Institute of America of Delray Beach, Florida (Press release, Entopsis, APR 21, 2020, View Source [SID1234556485]). Genetics Institute of America will create a laboratory developed test (LDT) based on Entopsis’ core diagnostic platform, OpsisDxTM . The purpose of the test will be to reduce or eliminate unnecessary prostate biopsies in men who are suspected of having prostate cancer.

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Current data show that only 34% of prostate biopsies result in a diagnosis of prostate cancer, resulting in thousands of unnecessary procedures each year, with resulting side effects and at great cost to the healthcare system. Early research data showed significant ability to stratify patients into the category of those who do not require prostate biopsy. Genetics Institute of America will run a prospective, Institutional Review Board approved validation study in its CLIA licensed facility and launch the laboratory developed test upon successful completion and acceptance of the study.

Entopsis is backed by Peter Thiel’s Breakout Labs and pursues the simple idea that an unbiased approach to diagnostics using signatures can be clinically and scientifically useful. In 2016, Entopsis was awarded the "Most Disruptive Technology Award" by the Greater Miami Chamber of Commerce.

"Our team of scientists and engineers have developed a uniquely impactful solution and are very excited to partner with the team at Genetics Institute of America in bringing OpsisDxTM to market," said Obdulio Piloto, PhD, Co-founder and CEO of Entopsis. "The ability to positively impact patients’ lives is one of the missions of Genetics Institute of America. Bringing the OpsisDxTM test to market has the potential to help improve urological care for thousands of men," said Holly Magliochetti, CEO and Founder of Genetics Institute of America.

Genetics Institute of America will recruit leading urologists as study sites having receiving IRB approval of the validation study protocol.