Sirtex Medical announces collaboration with MIM Software Inc.

On February 12, 2020 Sirtex Medical, a leading manufacturer of targeted liver cancer therapies, reported a collaboration with MIM Software Inc., a leading global provider of practical imaging solutions in the fields of radiation oncology, radiology, nuclear medicine, neuroimaging and cardiac imaging (Press release, Sirtex Medical, FEB 12, 2020, View Source [SID1234554247]). Under the terms of the agreement, Sirtex’s specialized sales teams in the United States, Europe and other key global markets will offer MIM SurePlanTM LiverY90 software alongside the company’s SIR-Spheres Y-90 resin microspheres to improve treatment precision for patients with hepatic tumors.

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MIM SurePlan LiverY90 provides timesaving tools and post-treatment dosimetry for interventional radiologists and nuclear medicine physicians treating hepatic tumors with SIR-Spheres. The software allows physicians to quickly calculate the dose delivered by the microspheres to improve treatment decisions and patient care. The technology also incorporates CT, PET, SPECT and MRI scans simultaneously to deliver results on spheres deposition, coverage and absorbed dose, allowing physicians to make informed decisions faster about next steps.

In addition to sharing a mission to provide physicians the tools they need to treat cancers, Sirtex and MIM also share a commitment to provide patients the best care throughout the treatment journey.

"Given the overlap of their technology and our SIR-Spheres product, Sirtex and MIM have a long history of working alongside clinical care teams," said Kevin Smith, Chief Executive Officer of Sirtex. "Now as partners, we will be able to combine our expertise and resources to provide an even higher level of support to treat liver tumors. We are excited to see how this collaboration will benefit physicians and ultimately improve treatment outcomes for patients."

"We are proud and excited to partner with Sirtex, mainly because it will provide access to personalized dosimetry for a large number of patients across the globe," said Andrew Nelson, Chief Executive Officer of MIM Software Inc. "The treatment of liver tumors requires a multi-disciplinary approach, so it’s a natural evolution for companies like ours to partner to provide an even faster, higher level of support and resources to treatment teams."

In the United States, SIR-Spheres Y-90 resin microspheres received Premarket Approval (PMA) from the FDA and are indicated for the treatment of non-resectable metastatic liver tumors from primary colorectal cancer in combination with intrahepatic artery chemotherapy using floxuridine. SIR-Spheres Y-90 resin microspheres are approved for the treatment of inoperable liver tumors in Australia, the European Union, Argentina, Brazil, Canada and several countries in Asia, such as India and Singapore.

About Selective Internal Radiation Therapy (SIRT) using SIR-Spheres Y-90 resin microspheres
SIR-Spheres Y-90 resin microspheres is a prescription device for the treatment of inoperable liver tumors. SIRT is a minimally invasive treatment that delivers high doses of high-energy beta radiation directly to the tumors. SIRT is administered to patients by interventional radiologists and nuclear medicine physicians, who infuse millions of radioactive resin microspheres via a catheter into the liver arteries that supply blood to the tumors. By using the tumors’ blood supply, the microspheres selectively target liver tumors with a dose of radiation that is up to 40 times higher than conventional radiotherapy, while sparing healthy tissue.

miR Scientific Presents Breakthrough New Data on the miR Scientific Sentinel™ Tests for the Detection and Classification of Prostate Cancer at the 2020 ASCO Genitourinary Cancers Symposium (February 13-15 in San Francisco, Calif.)

On February 12, 2020 miR Scientific LLC, reported that it will present the results of the recently completed Case-Control validation study of 1,436 patients consisting of 836 patients in a fully cross-validated training group and independent testing group of 600 patients (Press release, miR Scientific, FEB 12, 2020, View Source [SID1234554246]). The podium presentation will be in Oral Abstract Session A: Prostate Cancer at 1:10 p.m. on Thursday, February 13, 2020 and is titled Abstract 277: Analysis of small non-coding RNAs in urinary exosomes to classify prostate cancer into low-grade (GG1) and higher-grade (GG2-5).

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The study describes the miR Scientific Sentinel Disease Management Platform for Prostate Cancer which currently consists of three tests: The Sentinel PCa Test, that determines the presence or absence of prostate cancer, the Sentinel CS Test which identifies patients with low grade (GG1) or intermediate and high grade (GG2-GG5) prostate cancer and the Sentinel HG Test that identifies patients with high grade, high-risk cancer. Each test examines the expression levels of small non-coding RNAs (sncRNAs) extracted from urinary exosomes to diagnose, classify and monitor prostate cancer. The company’s classification algorithms identify and interrogate between 200-280 small non-coding RNAs using a customized, high throughput qPCR OpenArray platform for each test.

The results of the validation study demonstrate that the Sentinel PCa Test has a sensitivity of 94% and a specificity of 92%; the Sentinel CS Test has a sensitivity of 93% and a specificity of 90%; and the Sentinel HG Test has a sensitivity of 94% and a specificity of 96%. The performance characteristics of these tests support the company’s efforts to introduce the miR Scientific Disease Management Platform to mitigate poor outcomes and waste for patients and all key stakeholders, including healthcare providers, employers and payors. This validation now enables stakeholders to engage as early adopters worldwide. The combination of the three tests, which are standalone, do not require nor rely on any other testing nor risk analysis and can be performed on a single urine sample, providing a very precise platform for disease management, with high utility for diagnosing, classifying and monitoring prostate cancer.

"The results presented at ASCO (Free ASCO Whitepaper) GU demonstrate that the miR Scientific Sentinel Tests can transform clinical practice with broadly new and powerful capabilities to directly classify patients into actionable pathways: those with no evidence of prostate cancer, patients in need of definitive treatment, and patients eligible for active surveillance, which the Sentinel Tests can monitor," said Sam Salman, Chairman & CEO of miR Scientific. "The accuracy demonstrated by the miR Scientific Sentinel tests is significantly better than that of other current technologies and could prove to be even more accurate as we are currently ascertaining what proportion of this discordance represents misattribution of core needle biopsy histopathology or genuine misclassification errors of the Sentinel Tests. miR Scientific believes that the results suggest that the non-invasive Sentinel tests can be used as part of the Sentinel Prostate Cancer Disease Management Platform to provide patients and health care providers with an unprecedented level of information, allowing for more accurate and effective treatment of these cancers."

Renowned practitioners have expressed their confidence in these results. "The burden of over diagnosis and unnecessary treatments in prostate cancer worldwide is well known. What has been lacking is an effective, non-invasive tool to identify which patients may harbor aggressive cancers that are life threatening. The miR Scientific platform of liquid biopsy represents a highly sensitive and accurate way to identify these patients with less need for invasive procedures," said James M. McKiernan, M.D., the John K. Lattimer Professor and Chairman of the Department of Urology at Columbia University College of Physicians and Surgeons, Urologist in Chief, New York Presbyterian Hospital.

Evogene Financial Results for the Fourth Quarter and Full Year of 2019 Earnings Announcement Schedule

On February 12, 2020 Evogene Ltd. (NASDAQ: EVGN) (TASE: EVGN), a leading company in leveraging computational biology to design novel products for life-science-based industries including: human health, agriculture and industrial applications, reported that it will release its financial results for the fourth quarter and full year of 2019 on Wednesday, March 4, 2020 (Press release, Evogene, FEB 12, 2020, View Source [SID1234554245]).

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On the day of the announcement, the Company’s management will host a conference call to discuss the results at 09:00 AM Eastern time, 16:00 Israel time. To access the conference call, please dial 1-888-668-9141 toll free from the United States, or +972-3-918-0609 internationally. Access to the call will also be available via live webcast through the Company’s website at www.evogene.com.

A replay of the conference call will be available approximately three hours following the completion of the call. To access the replay, please dial 1-888-326-9310 toll free from the United States, or +972-3-925-5904 internationally. The replay will be accessible through March 4, 2019, and an archive of the webcast will be available on the Company’s website.

BioLife Solutions Announces Earnings Call Date and Upcoming Investor and Scientific Conferences

On February 12, 2020 BioLife Solutions, Inc. (NASDAQ: BLFS) ("BioLife" or the "Company"), a leading developer and supplier of a portfolio of best-in-class bioproduction tools for cell and gene therapies, reported the dates for several key events (Press release, BioLife Solutions, FEB 12, 2020, View Source [SID1234554244]):

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Q4 & FY2019 Earnings Conference Call

The Company’s fourth quarter and full year 2019 financial results will be released after market close on Wednesday, March 11, 2020 and the Company will host a conference call and live webcast at 4:30 p.m. ET (1:30 p.m. PT) that afternoon. Management will provide an overview of the Company’s financial results and a general business update.

To access the webcast, log on to the Investor Relations page of the BioLife Solutions website at www.biolifesolutions.com/earnings. Alternatively, you may access the live conference call by dialing (844) 825-0512 (U.S. & Canada) or (315) 625-6880 (International) with the following Conference ID: 9098230. A webcast replay will be available approximately two hours after the call and will be archived on www.biolifesolutions.com for 90 days.

Investor Conferences

Cowen 40th Annual Healthcare Conference; March 2-4, 2020: Boston Marriott Copley Place
2020 Stephens West Coast 1×1 Conference; March 12, 2020: The Palace Hotel, San Francisco
Oppenheimer 30th Annual Healthcare Conference; March 17-18, 2020: InterContinental New York Barclay
B. Riley FBR’s 21st Annual Institutional Investor Conference; May 20-21, 2020: Beverly Hilton
Scientific Conferences

CAR TCR Summit Europe; February 24-27, 2020: Hotel Novotel London West
Innate Killer Summit 2020 | Hanson Wade; March 24-26, 2020: Westin San Diego
Advanced Therapies Congress & Expo; March 30 – April 1, 2020: Business Design Centre, London
Massachusetts Association of Blood Banks (MABB); April 7-8, 2020: Mansfield, MA
American Association of Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting; April 24-29, 2020: San Diego Convention Center
American Society of Gene & Cell Therapy (ASGCT) (Free ASGCT Whitepaper) Annual Meeting; May 12-15, 2020; Hynes Convention Center, Boston
Allogeneic Cell Therapies Summit 2020 | Hanson Wade; May 19-21, 2020; Sheraton Boston Hotel
ISCT Annual Meeting; May 27-30, 2020: Palais des congres de Paris, France

Portola Pharmaceuticals to Announce Fourth Quarter and Full Year 2019 Financial Results on Wednesday, February 26, 2020

On February 12, 2020 Portola Pharmaceuticals, Inc. (NASDAQ: PTLA) reported that it will host a webcast and conference call to discuss the Company’s financial results for the fourth quarter and full year ended December 31, 2019, and provide a general business overview, on Wednesday, February 26, 2020, at 4:30 p.m. ET (1:30 p.m. PT) (Press release, Portola Pharmaceuticals, FEB 12, 2020, View Source [SID1234554243]).

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Conference Call Details
The live conference call on Wednesday, February 26, 2020, at 4:30 p.m. ET, can be accessed by phone by calling (844) 452-6828 from the United States and Canada or 1 (765) 507-2588 internationally and using the passcode 6192918. The webcast can be accessed live on the Investor Relations section of the Company’s website at View Source It will be archived for 30 days following the call.