Immutep TACTI-002 Data Presentation
at the AACR Virtual Annual Meeting 2020

On April 14, 2020 Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep" or "the Company"), a biotechnology company developing novel immunotherapy treatments for cancer and autoimmune diseases, reported that interim Phase II TACTI-002 clinical data has been selected for a poster short talk presentation as part of the high-impact paper presentation program at the American Association for Cancer Research (AACR) (Free AACR Whitepaper) Virtual Annual Meeting, scheduled for 27 and 28 April (Press release, Immutep, APR 14, 2020, View Source [SID1234556346]).

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This presentation was originally accepted as a late-breaking poster for the AACR (Free AACR Whitepaper) Annual Meeting prior to the event being rescheduled as two virtual events due to the ongoing COVID-19 pandemic, including AACR (Free AACR Whitepaper) Virtual Annual Meetings I and II. The data in this presentation relates to Immutep’s lead product candidate, eftilagimod alpha ("efti" or "IMP321"), a soluble LAG-3 protein based on the LAG-3 immune control mechanism, as part of a combination treatment with pembrolizumab, an anti-PD-1 therapy.

Presentation Details:

Title: ‘Initial results from a phase II study (TACTI-002) in metastatic non-small cell lung or head and neck carcinoma patients receiving eftilagimod alpha (soluble lag-3 protein) and pembrolizumab’
Date: Monday, April 27, 2020
Session: VPO.CT02.Phase II Clinical Trials: CT202
Presenter: Dr. Martin Forster, MBBS FRCP PhD, TACTI-002 clinical trial Principal Investigator, University College London Cancer Institute in the United Kingdom
The abstract title was published today on the AACR (Free AACR Whitepaper) website at View Source!/9045/presentation/10803.

The submitted abstract and the virtual poster presentation will also be accessible on Immutep’s website at www.immutep.com/investors-media/presentations.html on the day of the poster presentation.

TACTI-002 is being conducted in collaboration with Merck & Co., Inc., Kenilworth, NJ, USA (known as "MSD" outside the United States and Canada). It is evaluating the combination of efti with MSD’s KEYTRUDA (pembrolizumab) in up to 109 patients with second line HNSCC or NSCLC in first and second line.

Compugen to Present Data Update on COM701 Phase 1 Clinical Trial at the 2020 AACR Virtual Annual Meeting

On April 14, 2020 Compugen Ltd. (Nasdaq: CGEN), a clinical-stage cancer immunotherapy company and a leader in predictive target discovery, reported that it will present updates on its ongoing Phase 1 clinical trial evaluating COM701, a first-in-class therapeutic antibody targeting PVRIG, for the treatment of advanced solid tumors in an oral presentation at the 2020 American Association for Cancer Research (AACR) (Free AACR Whitepaper) Virtual Annual Meeting I on April 27, 2020 at 11:45 AM EST (Press release, Compugen, APR 14, 2020, View Source [SID1234556327]).

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The presentation, titled, "COM701 demonstrates preliminary antitumor activity as monotherapy and in combination with nivolumab in patients with advanced solid tumors", will include updates from the dose escalation arms of COM701 monotherapy and in combination with nivolumab. The presentation will be delivered by Ryan Sullivan, M.D., Assistant Professor, Medicine, Harvard Medical School and Assistant Professor, Hematology/Oncology, Massachusetts General Hospital.

The presentation will be made available on Compugen’s website at www.cgen.com following the conclusion of the presentation.

About COM701

COM701 is a humanized antibody that binds with high affinity to PVRIG, a novel immune checkpoint discovered computationally by Compugen, and blocks the interaction with its ligand, PVRL2. TIGIT, discovered by Compugen’s computational discovery platform in 2009, and PVRIG constitute parallel immune checkpoint pathways that counteract DNAM, a costimulatory molecule on T cells and NK cells. Preclinical data suggest that the blockade of PVRIG induces a robust anti-tumor immune response and demonstrates synergistic activity when used in combination with inhibitors of TIGIT and/or PD-1. Currently, COM701 is being evaluated in a Phase 1 clinical study. Data from the ongoing study have shown that COM701 is well-tolerated and demonstrated preliminary signs of anti-tumor activity in a heavily pretreated patient population.

BioMarin to Host First Quarter 2020 Financial Results Conference Call and Webcast on Thursday, April 30 at 4:30pm ET

On April 14, 2020 BioMarin Pharmaceutical Inc. (NASDAQ: BMRN) reported that Jean-Jacques Bienaimé, Chairman and Chief Executive Officer of BioMarin, will host a conference call and webcast on Thursday, April 30, at 4:30 p.m. ET to discuss first quarter 2020 financial results and provide a general business update (Press release, BioMarin, APR 14, 2020, View Source [SID1234556326]).

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Dial-in Number
U.S. / Canada Dial-in Number: (833) 360-0852
International Dial-in Number: (630) 652-5841
Conference ID: 6194595

Replay Dial-in Number: (855) 859-2056
Replay International Dial-in Number: (404) 537-3406
Conference ID: 6194595

Interested parties may access a live audio webcast of the conference call via the investor section of the BioMarin website, www.biomarin.com. A replay of the call will be archived on the site for one week following the call.

Cigna Corporation’s First Quarter 2020 Earnings Release Details

On April 14, 2020 Cigna Corporation (NYSE:CI) reported that it will release its first quarter 2020 financial results on Thursday, April 30, 2020 and will host a conference call on the same day (Press release, Cigna , APR 14, 2020, View Source [SID1234556325]).

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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First quarter 2020 financial results will be released no later than 6:30 a.m. Eastern Time (ET). Management will review these results on a conference call beginning at 8:30 a.m. ET that same morning. The call-in numbers for the conference call are as follows:

Live Call
(888) 324-7575 (Domestic)
(210) 234-0013 (International)
Passcode: 4302020

Replay
(866) 358-4539 (Domestic)
(203) 369-0140 (International)

It is strongly suggested you dial in to the conference call by 8:15 a.m. ET on April 30. A replay of the call will be available from 12:30 p.m. ET on Thursday, April 30 until 11:59 p.m. ET on Thursday, May 14, 2020. Additionally, the conference call will be available on a live Internet webcast at www.cigna.com under the About Cigna, Investor Relations section. Please note that this feature will be in listen-only mode.

A copy of the company’s news release and financial supplement will be available online at www.cigna.com under the About Cigna, Investor Relations section, no later than 6:30 a.m. ET on April 30.

IDEXX Laboratories to Release 2020 First Quarter Financial Results

On April 14, 2020 IDEXX Laboratories, Inc. (NASDAQ: IDXX), a global leader in veterinary diagnostics, veterinary practice software and water microbiology testing, reported that it has scheduled the release of its 2020 first quarter financial results for Thursday, April 30, 2020 before the market opens (Press release, IDEXX Laboratories, APR 14, 2020, View Source [SID1234556324]). The Company will host a conference call beginning at 8:30 a.m. ET on that day.

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Individuals can access a live webcast of the conference call through a link on the IDEXX website, www.idexx.com/investors. An archived edition of the webcast will be available after 1:00 p.m. ET on that day via the same link and will remain available for one year.

The live call also will be accessible by telephone. To listen to the live conference call, please dial 1-877-336-4441 or 1-409-207-6985 and reference access code 1103408.