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Nuvo Pharmaceuticals™ Update to Nuvo’s Presentation Time at H.C. Wainwright Global Investment Conference

On September 9, 2019 Nuvo Pharmaceuticals Inc. (Nuvo or the Company) (TSX:NRI;OTCQX:NRIFF), a Canadian focused, healthcare company with global reach and a diversified portfolio of commercial products, reported that Jesse Ledger, Nuvo’s President & Chief Executive Officer will present at the H.C. Wainwright 21st Annual Global Investment Conference to be held September 8-10, 2019 in New York City (Press release, Nuvo Pharmaceuticals, SEP 9, 2019, https://www.prnewswire.com/news-releases/nuvo-pharmaceuticals-update-to-nuvos-presentation-time-at-hc-wainwright-global-investment-conference-300913789.html [SID1234539389]).

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Updated Nuvo Presentation Details

Date:

Tuesday, September 10, 2019

Time:

4:15 p.m. ET (previously announced time 5:00 p.m. ET)

Location:

Lotte New York Palace Hotel

A link to the live audio webcast of the presentation will be available on the Home Page of the Company’s website at www.nuvopharmaceuticals.com. The archived webcast will be available for 30 days.

Mr. Ledger will be available during the conference for one-on-one meetings. Members of the investment community who are interested in meeting with the Company should contact conference coordinators to arrange an appointment or contact Nuvo directly via email at [email protected].

Cellular Biomedicine Group to Present at 5th Annual CAR-TCR Summit in Boston

On September 9, 2019 Cellular Biomedicine Group Inc. (NASDAQ: CBMG) ("CBMG" or the "Company"), a biopharmaceutical firm engaged in the drug development of immunotherapies for cancer and stem cell therapies for degenerative diseases, reported that the Company will present at the upcoming Annual CAR-TCR Summit in Boston, MA September 10-13, 2019 (Press release, Cellular Biomedicine Group, SEP 9, 2019, View Source [SID1234539388]).

Wednesday, September 11, 2:47pm
Yihong Yao, PhD, Chief Scientific Officer
"Meeting the Challenge of Delivering Cell & Gene Therapy Products to Patients in China"

Medical digitalization will fundamentally transform research, clinical, and healthcare as a whole
How China can advance the progress in novel therapy modalities
De-risking clinical trials by leveraging fast-track clinical studies
A copy of the presentation will be made available on the Company’s website following the presentation.

Jubilant Life Sciences Announces Appointment of Dr. Syed Kazmi as President and CEO of its New Innovative Biopharmaceutical Company in the U.S. – Jubilant Therapeutics Inc.

On September 9, 2019 Jubilant Life Sciences Limited has reported that Dr. Syed Kazmi, PhD, MBA, will join its new innovative biopharmaceutical company in the U.S., Jubilant Therapeutics Inc., as President and Chief Executive Officer (Press release, Jubilant Life Sciences, SEP 9, 2019, View Source;jubilant-therapeutics-inc-300914090.html [SID1234539387]).

Dr. Kazmi joins from Novartis Pharmaceuticals Corporation where he was Vice President, Global Head of Business Development & Licensing for Oncology.

Earlier this year, Jubilant Life Sciences spun off select proprietary innovation assets that are in various stages of discovery and development into Jubilant Therapeutics. The new company has a unique business model with a combination of semi-virtual set up and significant synergies with rest of Jubilant Life Sciences including strategic partnership with Jubilant Biosys, a world-class preclinical CRO.

Jubilant Therapeutics’ strategy is to discover and develop novel small molecule modulators of important and previously undruggable targets primarily in oncology and establish creative partnerships to bring innovative therapeutics to patients in need.

The Company’s current pipeline includes a novel dual epigenetic inhibitor of LSD1/HDAC6 to address unmet needs in liquid cancers like acute myeloid leukemia (AML), a small molecule PDL-1 therapy with comparable efficacy to large molecules and lower side effects, a small molecule PAD4 inhibitor with potential to address unmet needs in multiple auto-immune disorders and a PRMT5 inhibitor for lymphoma.

"We extend a warm welcome to Syed as the CEO of Jubilant Therapeutics," said Shyam Bhartia and Hari Bhartia, Chairman and Co-Chairman of Jubilant Life Sciences. "Syed has had an accomplished career of over 25 years in M&A, licensing, strategic collaborations, and R&D in both specialty biotech and large pharma companies. We are confident that his extensive experience will help make Jubilant Therapeutics a successful global clinical stage biopharmaceutical company with the mission of transforming the lives of patients with serious diseases."

"I am honored to join as CEO to continue building the pipeline assets and collaborations to fast-track new innovative drugs to market. I look forward to growing Jubilant Therapeutics into a first-in-class biopharma company," said Syed Kazmi.

BioMarin to Participate in Morgan Stanley 17th Annual Global Healthcare Conference on September 10, 2019 in New York

On September 9, 2019 BioMarin Pharmaceutical Inc. (NASDAQ: BMRN), reported that Dan Spiegelman, Executive Vice President and Chief Financial Officer and Henry Fuchs, M.D., President, Worldwide Research & Development, will present at the Morgan Stanley 17th Annual Global Healthcare Conference on September 10, 2019 at 8:35am ET in New York (Press release, BioMarin, SEP 9, 2019, View Source [SID1234539386]). To access the live webcast, please visit the investor section of the BioMarin website, www.biomarin.com. A replay will also be archived on the site for at least one week following each event.

Novocure Announces 27 Presentations at the American Society for Radiation Oncology 2019 Annual Meeting

On September 9, 2019 Novocure (NASDAQ: NVCR) reported 27 presentations on Tumor Treating Fields, including four oral presentations, will be featured at the American Society for Radiation Oncology (ASTRO) 2019 Annual Meeting, Sept. 15 through Sept. 18 in Chicago (Press release, NovoCure, SEP 9, 2019, View Source [SID1234539381]). The volume of Tumor Treating Fields presentations marks a record number of abstracts for Novocure at this conference. External authors prepared 16 of the presentations, pointing to a growing interest in Novocure’s proprietary Tumor Treating Fields platform within the radiation oncology community.

Presentation highlights include a subgroup analysis of the STELLAR trial by radiological response patterns in malignant pleural mesothelioma and the first presentation of in vitro data combining treatment with Tumor Treating Fields and chemotherapy in gastric cancer.

"The presence of Tumor Treating Fields at the ASTRO Annual Meeting has grown substantially over the last three years," said Novocure’s Chief Medical Officer Ely Benaim. "We are excited to continue our partnership with the radiation oncology community to help establish Tumor Treating Fields as an important treatment for solid tumors. We look forward to participating in the exchange of scientific information at one of the premier meetings for radiation oncologists."

Oral Presentations

(Presentation 1070) Radiological Response Patterns in Malignant Pleural Mesothelioma (MPM): Subgroup Analyses of the Phase 2 STELLAR Trial of TTFields plus Chemotherapy for First-Line Treatment. F. Grosso. 8:40 to 8:45 a.m. CDT Monday, Sept.16.

(Presentation 1102) Blood Brain Barrier (BBB) Integrity is Affected By Tumor Treating Fields (TTFields) in Vitro and In Vivo. C. Hagemann. 4:25 to 4:30 p.m. CDT Monday, Sept.16.

(Presentation 212) Creating Conductivity Maps at 200 Khz of Brain and Tumor Tissue of Glioblastoma Patients with Water-Content Based Electric Properties Tomography. N. Gentilal. 1:55 to 2:05 p.m. CDT Wednesday, Sept. 18.

(Presentation 1277) Tumor Treating Fields Delivery to the Abdomen Is Unlikely to Cause Thermal Tissue Damage: Results of an Extensive Computational Analysis. N. Gentilal. 2:25 to 2:30 p.m. CDT Wednesday, Sept. 18.

Joint Interactive Session

Novel targeted therapies/Immuno-oncology and Clinical Trials/TTF. M. Ahluwalia. 4:32 to 4:44 p.m. CDT Monday, Sept. 16.

Poster Presentations

(3109) Efficacy and Thermal Safety of Tumor Treating Fields Delivered to the Thorax: A Simulation-Based Study. Z. Bomzon. 1:15 to 2:30 p.m. CDT Sunday, Sept. 15.

(3116) Malignant Pleural Mesothelioma: Survival Meta-Analysis from 15 Years of a Standard Systemic Therapy. J. Friedberg. 1:15 to 2:30 p.m. CDT Sunday, Sept. 15.

(3254) Clinical Value of TTFields Treatment in Mesothelioma Using ASCO (Free ASCO Whitepaper) and ESMO (Free ESMO Whitepaper) Frameworks. J. Kelly. 1:15 to 2:30 p.m. CDT Sunday, Sept. 15.

(3611) Animal Studies Evaluating the Safety of Tumor Treating Fields (TTFields) Alone and in Combination with Chemotherapy Agents Demonstrate No Additional Toxicities. M. Giladi. 1:15 to 2:30 p.m. CDT Sunday, Sept. 15.

(2159) Delivering Uniform TTFields Distribution to the Brain. Z. Bomzon. 10:45 to 12 p.m. CDT Monday, Sept. 16.

(2214) Prostaglandin E Receptor 3 Mediates Resistance to Tumor Treating Fields in Glioblastoma Cells. D. Chen. 10:45 to 12 p.m. CDT Monday, Sept. 16.

(2222) Tumor Treating Fields Combined with Radiotherapy and Temzolomide for the Treatment of Newly Diagnosed Glioblastoma: Final Results from a Pilot Study. R. Grossman. 10:45 to 12 p.m. CDT Monday, Sept. 16.

(2226) Analysis of the EF-14 Phase 3 Trial Reveals That Tumor Treating Fields Alter Progression Patterns in Glioblastoma. S. Jeyapalan. 10:45 to 12 p.m. CDT Monday, Sept. 16.

(2287) A Proof of Concept Study for Simulating Heat Transfer in Patients Treated with Tumor Treating Fields. Z. Bomzon. 10:45 to 12 p.m. CDT Monday, Sept. 16.

(2240) Single Institutional Experience with Tumor Treating Field Compliance and Overall Survival in Patients with Primary Glioblastoma. K. Qualls. 10:45 a.m. to 12 p.m. CDT Monday, Sept. 16

(3003) Treating Elderly Glioblastoma Patients > 65 Years with TTFields: A Cost-Effectiveness Perspective. F. Leonard. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3362) Updated Meta-Analysis of Toxicity Data in Thoracic and Abdominal Malignancies from Clinical Trials in Tumor Treating Fields. I. Vergote. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3486) Exploiting Conditional Vulnerabilities Caused By the Systems Level Effects of Tumor Treating Fields. M. Story. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3498) TTFields Induces Immunogenic Cell Death and Sting Pathway Activation through Cytoplasmic Double-Stranded DNA in Glioblastoma Cells. D. Chen. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3541) Tumor Treating Fields (TTFields) Suppress Tunneling Nanotube Formation in Malignant Mesothelioma. A. Sarkari. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3581) Patient-Derived Metastatic Non-Small Cell Lung Cancer (NSCLC) Cell Lines from Untreated and Treated Patients Are Sensitive to Tumor Treating Fields (TTFields) in Vitro. S. Michelhaugh. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3573) Tumor Treating Fields (TTFields) Plus Sorafenib Is Safe and Effective in Hepatocellular Carcinoma Tested in Vitro and in an Animal Model. S. Davidi. 1 to 2:15 p.m. CDT Tuesday, Sept.17.

(3514) Immunogenic Cell Death Induced by Tumor Treating Fields (TTFields) Enhances Efficacy When Combined with Anti-PD-1 Therapy in Lung and Colon Cancer Animal Models. T. Voloshin. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3582) Efficacy of Tumor Treating Fields (TTFields) in Combination with Cisplatin or Pemetrexed for the Treatment of Mesothelioma in Vitro and in Vivo. M. Munster. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3587) The Combined Treatment of 150 kHz Tumor Treating Fields (TTFields) and FOLFOX Inhibit Gastric Cancer in Vitro. E. Zeevi. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3845) Tumor Treating Fields Therapy Influences Patterns of Failure in Glioblastoma Patients in a Dose-Dependent Manner: A Multidisciplinary Analysis of the Randomized Phase III EF-14 Clinical Trial. M. Ballo. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.

(3857) Optimizing Transducer Array Layout for the Treatment of Pancreatic Cancer Using Tumor Treating Fields (TTFields) in the Phase 3 PANOVA-3 Trial. Z. Bomzon. 1 to 2:15 p.m. CDT Tuesday, Sept. 17.