1stOncology™: Cancer Intelligence Service – Page 14339 – 1stOncology is recognized as a Top 10 Global Pharma Analytic Provider

Merck to Hold Fourth-Quarter and Full-Year 2018 Sales and Earnings Conference Call on February 1

On January 22, 2019 Merck (NYSE: MRK), known as MSD outside the United States and Canada, reported that it will hold its fourth-quarter and full-year 2018 sales and earnings conference call with institutional investors and analysts at 8:00 a.m. EST on Friday, Feb. 1 Merck (NYSE: MRK), known as MSD outside the United States and Canada, will hold its fourth-quarter and full-year 2018 sales and earnings conference call with institutional investors and analysts at 8:00 a.m. EST on Friday, Feb. 1. During the call, company executives will provide an overview of Merck’s performance for the quarter.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

Schedule Your 30 min Free Demo!

Investors, journalists and the general public may access a live audio webcast of the call on Merck’s website at View Source A replay of the webcast, along with the sales and earnings news release and supplemental financial disclosures, will be available at www.merck.com.

Institutional investors and analysts can participate in the call by dialing (706) 758-9927 or (877) 381-5782 and using ID code number 9872199. Members of the media are invited to monitor the call by dialing (706) 758-9928 or (800) 399-7917 and using ID code number 9872199. Journalists who wish to ask questions are requested to contact a member of Merck’s Media Relations team at the conclusion of the call.

. During the call, company executives will provide an overview of Merck’s performance for the quarter.

BiocurePharm, Korea (“BPK”) Announces Private Placement

On January 21, 2019 Biocure Technology Corp. ("CURE" or the "Company") (CSE:CURE; OTCQB: BICTF) BiocurePharm, Korea ("BPK"), a wholly owned subsidiary of Biocure Technology Inc. ("CURE") reported that it has arranged a non- brokered private placement through its Korean Subsidiary BiocurePharm, Korea ("BPK"), BPK will be issuing up to 100,000 shares at 11,40 CAD per share for gross proceeds of $1.14 Million or more, depending on investor interest (Press release, Biocure Technology, JAN 21, 2019, View Source [SID1234628758]). Finder’s fees or commissions may be payable by the Company in connection with this Private Placement.

The net proceeds from the non-brokered private placement are intended to be used for general working capital and research and development.

RadioMedix received $2 M SBIR Phase II Contract award from NCI NIH for the targeted alpha-emitter therapy of neuroendocrine cancers

On January 21, 2019 RadioMedix Inc. is reported that the company has been awarded a two-year, $2.0 M Phase II SBIR contract award by the NIH NCI (HHSN261201800048C; UPIID:75N91018C00048) for the clinical development of Targeted Alpha-emitter Therapy (TAT) of neuroendocrine tumors (Press release, RadioMedix, JAN 21, 2019, View Source [SID1234532801]). This Phase II Contract award is a continuation of the successfully completed Phase I SBIR contract (HHSN261201600015C). This award will support the Phase I, non-randomized, open-label, dose escalation study to determine the safety, bio-distribution, and preliminary effectiveness of 212Pb-octreotate analog (AlphaMedix) in adult subjects with Somatostatin Receptor (SSTR) expressing neuroendocrine tumors (NCT03466216). Dr. Izabela Tworowska (RadioMedix) serves as a Principal Investigator of the SBIR Phase II contract and is working together with Dr. Julien Torgue (co-I, Orano Med). The clinical studies are currently on-going at the Excel Diagnostics and Nuclear Oncology Center (Houston, TX).

"Patients with advanced Neuroendocrine Tumors (NETs) have limited treatment options available to them. Our goal is to address this unmet clinical need by using targeted alpha-emitter therapy", said Izabela Tworowska, PhD, CSO of RadioMedix. "We are grateful to NCI for acknowledging the importance of alpha-emitter therapy and supporting our clinical studies of 212Pb-octreotate analog. This SBIR Phase II Contract is the second award highlighting RadioMedix – Orano Med collaboration."

"TAT is believed to be the next generation of radiopharmaceuticals in the field of Radioligand Therapy (RLT) in oncology. Our proprietary 212Pb labeled agent has potential to advance the effectiveness of Peptide Receptor Radionuclide therapy (PRRT) as compared to currently approved PRRT agents for neuroendocrine cancers", said Dr. Ebrahim S. Delpassand, CEO of RadioMedix. "Unique properties of 212Pb can induce targeted and irreversible damage to the cancer cells, which can result in significant clinical benefits to NET patients", added Dr. Delpassand.

This project has been funded in part with Federal funds from the National Cancer Institute, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN261201800048C.

Lilly Confirms Date and Conference Call for Fourth-Quarter 2018 Financial Results Announcement

On January 21, 2019 Eli Lilly and Company (NYSE: LLY) reported that it will announce its fourth-quarter and full-year 2018 financial results on Wednesday, February 13, 2019 (Press release, Eli Lilly, JAN 21, 2019, View Source [SID1234532800]). Lilly will also conduct a conference call on that day with the investment community and media to further detail the company’s financial performance.

The conference call will begin at 9 a.m. Eastern time. Investors, media and the general public can access a live webcast of the conference call through a link that will be posted on Lilly’s website at View Source A replay will also be available on the website following the conference call.

AIVITA Biomedical to Present at Upcoming January Healthcare Conferences

On January 21, 2019 AIVITA Biomedical, Inc., a biotech company specializing in innovative stem cell applications, reported the company will be presenting at two upcoming healthcare conferences. AIVITA’s Chief Medical Officer Dr. Robert O. Dillman will be presenting at Precision Medicine World Conference on Tuesday, Jan. 22, in Santa Clara, California. AIVITA Chairman and Chief Executive Officer Dr. Hans S. Keirstead will speak at Phacilitate Leaders World on Wednesday, Jan. 23, in Miami, Florida.

Precision Medicine World Conference in Silicon Valley is a healthcare conference for that provides attendees with an opportunity to learn about the latest developments and advancements in precision medicine. Dr. Dillman will be presenting details on AIVITA’s autologous cancer vaccine technology on Tuesday, Jan. 22, at 2:45 p.m. in a talk titled Patient-Specific Cancer Vaccines. He will share past and current clinical data in a presentation focused on antigens from autologous tumor initiating cells.

Co-located with the World Stem Cell Summit, Phacilitate Leaders World is an advanced therapies partnering event that provides attendees with a platform to build new partnerships and discuss cutting-edge therapies. On Wednesday, Jan. 23, at 2:35 p.m. Dr. Keirstead will deliver a talk titled Targeting the Cancer Stem Cell: Clinical Data and Mechanism of Action.

About ROOT OF CANCER

AIVITA’s treatment is a platform technology applicable to most solid tumor types and consists of autologous dendritic cells loaded with autologous tumor antigens from autologous self-renewing tumor-initiating cells.

AIVITA’s ovarian Phase 2 double-blind study is active and enrolling approximately 99 patients who will be randomized in a 2:1 ratio to receive either the autologous dendritic cell vaccine or autologous monocytes as a comparator.

Patients eligible for randomization and treatment will be those (1) who have undergone debulking surgery, (2) for whom a cell line has been established, (3) who have undergone leukapheresis from which sufficient monocytes were obtained, (4) have an ECOG performance grade of 0 or 1 (Karnofsky score of 70-100%), and (5) who have completed primary therapy.

For additional information about AIVITA’s AVOVA-1 trial patients can visit: www.clinicaltrials.gov/ct2/show/NCT02033616

AIVITA’s glioblastoma Phase 2 single-arm study is active and will enroll approximately 55 patients to receive the treatment candidate.

Patients eligible for treatment will be those (1) who have recovered from surgery such that they are about to begin concurrent chemotherapy and radiation therapy (CT/RT), (2) for whom an autologous tumor cell line has been established, (3) have a Karnofsky Performance Status of > 70 and (4) have undergone successful leukapheresis from which peripheral blood mononuclear cells (PBMC) were obtained that can be used to generate dendritic cells (DC).