Anocca raises SEK 400 million for large-scale development of cancer cell therapies

On May 31, 2023 Anocca AB reported that the company has successfully raised SEK 400 million through an equity financing round led by AMF and Mellby Gård (Press release, Anocca, MAY 31, 2023, View Source [SID1234632255]). The capital injection will be used to further develop the company’s unique process that enables discovery and manufacture of next generation cell therapies for cancer on an industrial scale. The financing also allows Anocca to progress the company’s first products into clinical trials.

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The financing brings together a solid group of existing and new investors, including Mellby Gård, AMF, Michano, Swedbank Robur, Ramsbury, Nidoco and several well-known family offices and private investors.

"In recent years, we have made great progress in automating our research platform. In addition, our large-scale and precise analytical methods have allowed us to generate additional data that strengthens the first products that will enter clinical trials. The capital injection will fund the continued expansion of Anocca’s research, development, and manufacturing capabilities as well as the start of a first clinical trial which is planned to be initiated in 2024," says Reagan Jarvis, CEO of Anocca.

Anocca uses proprietary analytical methods to identify and produce a kind of immune cell, T-cells, that have the ability fight a specific tumour. These processes are unique and Anocca aims to be the first company that on an industrial scale can identify suitable targets on tumour cells and generate matching T-cell receptors (TCRs), a type of receptor that controls the activity of the immune system’s T-cells. Each active TCR identified by Anocca can be further developed into a highly specialised cancer treatment, or a "TCR-T" therapy.

"We appreciate the opportunity to invest in such an interesting and important Swedish research company as Anocca. The company operates at the forefront of cancer research and drug development, with its ability to create a broad range of therapies with high precision. They have an impressive capacity and position already today, and very interesting plans for future expansion and development. We look forward to being a part of Anocca’s future growth journey and believe that this will be an investment that will be beneficial for our pension holders, as well as for Sweden, Swedish research, and for patients that will have access to more effective treatments due to Anocca’s breakthrough solutions," says Anders Oscarsson, Head of Equities at AMF.

In recent years, cell therapies have shown enormous potential in the treatment of cancer. The cell therapies used in practice today, CAR-T, have revolutionised the treatment of some cancers but are effective in less than 10% of all tumours. Despite this, CAR-T has quickly created a multi-billion-dollar market. The next generation of cell therapies, TCR-T, unlike CAR-T, has the potential to target virtually all forms of cancers.

"Anocca’s unique process creates almost endless opportunities to generate new TCR-Ts on a continuous basis. This means that we now have the chance to establish a Swedish company as a global leader in future cancer treatments," says Hans Stråberg, Chairman of the Board of Anocca.

Anocca was founded in 2014 and currently has 100 employees. The company’s operations include both research and manufacturing and are located at former AstraZeneca facilities in Södertälje. In recent years, Anocca has focused on automating and expanding its platform to identify the right targets on tumour cells and matching TCRs, while preparing for regulatory approval of the manufacturing facility. Including the current capital raise, Anocca has received a total of SEK 1.3 billion in venture capital. In addition, in December 2022, Anocca was granted a venture debt facility from the European Investment Bank (EIB) of EUR 25 million.

Danske Bank acted as financial advisor to Anocca in the transaction.

Alkermes to Participate in Two Upcoming Investor Conferences

On May 31, 2023 Alkermes plc (Nasdaq: ALKS) reported that management will participate in fireside chats at two upcoming investor conferences (Press release, Alkermes, MAY 31, 2023, View Source [SID1234632254]).

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Jefferies Healthcare Conference
Date/Time: Wednesday, June 7, 2023 at 10:00 a.m. EDT (3:00 p.m. BST)

Goldman Sachs 44th Annual Global Healthcare Conference
Date/Time: Monday, June 12, 2023 at 9:20 a.m. PDT (12:20 p.m. EDT/5:20 p.m. BST)

The live webcasts may be accessed under the Investors tab on www.alkermes.com and will be archived for 14 days.

ALENTIS THERAPEUTICS TO PARTICIPATE IN THE ASCO ANNUAL MEETING AND BIO INTERNALTIONAL CONVENTION

On May 31, 2023 Alentis Therapeutics ("Alentis"), the Claudin-1 company, reported its participation in the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper) to be held June 2-6 in Chicago, IL, and the BIO International Convention to be held June 5-8 in Boston, MA (Press release, Alentis Therapeutics, MAY 31, 2023, View Source [SID1234632253]).

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Alentis management will be present at the conferences. In case you want to schedule a meeting please reach out via [email protected].

Acorda Therapeutics to Conduct 1-for-20 Reverse Stock Split

On May 31, 2023 Acorda Therapeutics, Inc. (Nasdaq: ACOR) reported that it will conduct a reverse stock split of its outstanding and authorized shares of common stock at a ratio of 1-for-20 (Press release, Acorda Therapeutics, MAY 31, 2023, View Source [SID1234632251]). The reverse stock split will become effective at 4:01 p.m. Eastern Time, on June 2, 2023. The Company’s common stock will begin trading on a post-split basis at the market open on June 5, 2023. The reverse stock split is being effected to regain compliance with the $1.00 per share minimum closing price required to maintain continued listing on The Nasdaq Global Select Market.

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The reverse stock split will apply equally to all outstanding shares of the common stock, and each stockholder will hold the same percentage of common stock outstanding immediately following the reverse stock split as that stockholder held immediately prior to the reverse stock split, except for adjustments that may result from the treatment of fractional shares. The Company will not issue any fractional shares in connection with the reverse stock split, and the number of shares issued will be rounded up to the next whole share. The reverse stock split will not modify the rights or preferences of the common stock. As a result of the proportionate reduction in the number of authorized shares of common stock, the reverse stock split will result in the number of authorized shares of common stock being reduced from 61,666,666 to 3,083,333.

As previously reported in the Company’s Current Report on Form 8-K filed on November 14, 2022, on November 11, 2022, the Company’s stockholders approved a proposal to authorize the Company’s board of directors to approve an amendment and restatement of the Company’s certificate of incorporation to effect a reverse stock split of the Company’s common stock by a ratio of any whole number in the range of 1-for-2 to 1-for-20, and a corresponding reduction in the number of authorized shares of the Company’s common stock, within one year following the conclusion of the Special Meeting of Stockholders on November 11, 2022.

Dynavax to Present at Upcoming Investor Conferences

On May 30, 2023 Dynavax Technologies Corporation (Nasdaq: DVAX), a commercial-stage biopharmaceutical company developing and commercializing innovative vaccines, reported that the Company will present at the following upcoming investor conferences during the month of June (Press release, Dynavax Technologies, MAY 30, 2023, View Source [SID1234632265]):

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William Blair 43rd Annual Growth Stock Conference on Tuesday, June 6 at 9:20 a.m. CT

Goldman Sachs 44th Annual Global Healthcare Conference on Monday, June 12 at 11:20 a.m. PT

The presentations will be webcast and may be accessed through the "Events & Presentations" page on the "Investors" section of the Company’s website at View Source