Bristol Myers Squibb to Participate in Citi’s 17th Annual BioPharma Conference

On August 31, 2022 Bristol Myers Squibb (NYSE: BMY) reported that the company will take part in a fireside chat at Citi’s 17th Annual BioPharma Conference on Thursday, September 8, 2022 in Boston, Massachusetts (Press release, Bristol-Myers Squibb, AUG 31, 2022, View Source [SID1234618821]). Company executives will answer questions about the company at 8:50 a.m. ET.

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Investors and the general public are invited to listen to a live webcast of the session at View Source An archived edition of the session will be available later that day.

Exercise of Options

On August 31, 2022 ImmuPharma plc (LSE : IMM), the specialist drug discovery and development company, reported that L1 Capital Global Opportunities Master Fund ("L1") has exercised Options over 2,000,000 new ordinary shares of 1p each ("Ordinary Shares") at an exercise price of 5p per share, for a consideration of £100,000 (Press release, ImmuPharma, AUG 31, 2022, View Source [SID1234618820]).

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New Ordinary Shares and Admission

The New Ordinary Shares have been allotted today and are issued credited as fully paid and will rank pari passu in all respects with the Company’s existing issued ordinary shares.

An application will be made for the New Ordinary Shares to be admitted to trading on the AIM market ("Admission") of the London Stock Exchange. It is anticipated that Admission will occur on or around Monday 5 September 2022.

The New Ordinary Shares represent 0.61% of the Company’s enlarged issued share capital.

Total Shares in Issue

For the purposes of the Disclosure Guidance and Transparency Rules of the Financial Conduct Authority ("DTR"), the Board of ImmuPharma hereby notifies the market that following Admission, the Company’s total issued share capital will consist of 330,403,115 Ordinary Shares with a nominal value of 1p each.

This figure may be used by Shareholders as the denominator for the calculations by which they may determine if they are required to notify their interest in, or a change to their interest in, the Company under the DTR.

This announcement contains inside information for the purposes of Article 7 of EU Regulation 596/2014.

Revolution Medicines to Participate in Upcoming Investor Conferences

On August 31, 2022 Revolution Medicines, Inc. (Nasdaq: RVMD), a clinical-stage oncology company developing targeted therapies for RAS-addicted cancers, reported that the company will participate in two upcoming investor conferences (Press release, Revolution Medicines, AUG 31, 2022, View Source [SID1234618818]). Mark A. Goldsmith, M.D., Ph.D., chief executive officer and chairman of Revolution Medicines, will be the featured speaker in fireside chats at the 2022 Wells Fargo Healthcare Conference and the H.C. Wainwright 24th Annual Global Investment Conference.

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Details of these events are as follows:

2022 Wells Fargo Healthcare Conference
Conference Date: September 7-9, 2022
Fireside Chat Time/Date: 3:45 – 4:15 p.m. Eastern on Thursday, September 8, 2022
Format: In-person conference located at Encore Boston Harbor
H.C. Wainwright 24th Annual Global Investment Conference
Conference Date: September 12-14, 2022
Fireside Chat Time/Date: 7:00 a.m. Eastern on Monday, September 12, 2022
Format: Hybrid event (in-person and virtual); webcast available
A webcast of the H.C. Wainwright fireside chat can be accessed at: View Source An archived replay of the webcast will be available on the investors section of the company’s website for at least 14 days following the event.

BioCryst to Present at Upcoming Investor Conferences

On August 31, 2022 BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) reported that the company will present at the 2022 Wells Fargo Healthcare Conference on Wednesday, September 7, 2022 at 11:35 a.m. ET and the H.C. Wainwright 24th Annual Global Investment Conference (Press release, BioCryst Pharmaceuticals, AUG 31, 2022, View Source [SID1234618817]). A pre-recorded fireside chat for the H.C. Wainwright conference will be made available Monday, September 12, 2022, at 7:00 a.m. ET.

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Links to live audio webcasts and replays of the presentations may be accessed in the Investors & Media section of BioCryst’s website at http://www.biocryst.com.

Ensysce Biosciences and Quotient Sciences Announce a Partnership on the Development and Clinical Testing of Ensysce’s PF614-MPAR, a Novel Opioid Designed to Prevent Abuse and Overdose

On August 31, 2022 Ensysce Biosciences, Inc. ("Ensysce" or the "Company") (NASDAQ:ENSC)(OTC PINK:ENSCW), a clinical-stage biotech company applying transformative chemistry to improve prescription drug safety, and Quotient Sciences, a drug development and manufacturing accelerator, reported a partnership to support the development and clinical testing of PF614-MPAR (Press release, Ensysce Biosciences, AUG 31, 2022, View Source [SID1234618816]).

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PF614-MPAR is a novel opioid combination product for the potential treatment of chronic pain that is designed to prevent both abuse and overdose.

Quotient Sciences is currently using its integrated Translational Pharmaceutics platform to identify a PF614-MPAR formulation that allows conversion into oxycodone within the prescribed dose range but reduces conversion to oxycodone at higher than prescribed dose levels in an overdose scenario.

The formulation will be an optimized composition that balances dose and release rate, with the candidate formulations being tested in the clinic having been selected from emerging clinical data in order to achieve the desired exposure profile, allowing formulation optimization in humans rather than preclinical species.

Mark Egerton, PhD, CEO of Quotient Sciences, said: "We are pleased to be partnering with Ensysce to accelerate the development of their PF614-MPAR program. Quotient Sciences’ ability to integrate formulation and clinical services under a single organization will expedite Ensysce’s development timeline and provide patients who are suffering with a safer option for pain relief faster."

Lynn Kirkpatrick, PhD, CEO of Ensysce Biosciences, commented: "Opioids have been a longstanding and important type of treatment for moderate to severe pain, but they are prone to abuse and overdose. This widespread problem for patients and society results in significant cost to the healthcare system, which we are trying to address with our two proprietary technology platforms."

"The PF614-MPAR program is designed to fill a great unmet need for effective pain medications that reduce the risk of abuse and specifically prescription drug overdose. This partnership serves as validation of our mission and ultimately our platforms. We continue to make strong progress towards our clinical development of PF614 and are excited to partner with Quotient Sciences to develop PF614- MPAR, as we believe we will be bringing to market important therapeutic options for those in severe pain."