On February 22, 2022 Cumulus Oncology, Europe’s first oncology biotech creation company, reported that it has secured a £4.1 million ($5.6 million) investment led by St Andrews-based investment firm Eos Advisory (Press release, Cumulus Oncology, FEB 22, 2022, View Source [SID1234608825]). Scottish Enterprise invested alongside Eos as Cumulus plans further scale, while an additional £1.5 million ($2 million) will follow in the coming months.

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Cumulus was founded in 2017 to identify novel oncology assets to de-risk and add value to, before creating spin-out companies to commercialise novel cancer therapies. After founding Nodus Oncology in April 2020 to conduct research into DNA damage response (DDR), Cumulus formed Modulus Oncology in September 2020 alongside the University of Sheffield.

CEO and co-founder Clare Wareing said: "With the support of our cornerstone investors, we will accelerate our business model to identify and develop new oncology treatments that target the unmet medical needs of specific cancer patient populations."

Andrew McNeill, Managing Partner, Eos Advisory, said: "Clare and her team have made tremendous progress over the last few years, are at the forefront of their field in the European context, and we are pleased to continue our support of the business as Cumulus enters its next phase of growth."

Kerry Sharp, Director of Growth Investments at Scottish Enterprise, said: "It’s fantastic to see the progress Cumulus Oncology is making in the field of cancer therapies. With Scottish Enterprise investment, which focuses on early stage high growth potential companies, this company can continue to develop its ambitious plans."

Cumulus is also announcing that Dr Russell Greig will be joining the board as Chairman. Greig, a GlobalScot, spent much of his career working on both the drug development and investment sides of the business at GlaxoSmithKline, where he held a number of positions including President, International Pharmaceuticals, and Senior Vice President, Worldwide Business Development. More recently, he has held board roles for a series of biotechs and has advised life science VCs and biotechnology companies in the USA, Europe, and Asia via his Philadelphia-based Greig Biotechnology Global Consulting business.

Dr Russell Greig, Chairman, Cumulus Oncology, said: "Cumulus has established a unique position in Europe, and is set to make an impact further afield in other regions including North America. I look forward to helping to guide Clare and her expert team around strategic focus over the months and years ahead."

On February 22, 2022 Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, reported that it will report fourth quarter and full-year 2021 financial results after the Nasdaq Global Market closes on Tuesday, March 1, 2022 (Press release, Sarepta Therapeutics, FEB 22, 2022, View Source [SID1234608824]). Subsequently, at 4:30 p.m. E.T., the Company will host a conference call to discuss its fourth quarter and full-year 2021 financial results and to provide a corporate update.

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The conference call may be accessed by dialing (844) 534-7313 for domestic callers and (574) 990-1451 for international callers. The passcode for the call is 8075225. Please specify to the operator that you would like to join the "Sarepta Fourth Quarter and Full-Year 2021 Earnings Call." The conference call will be webcast live under the investor relations section of Sarepta.com and will be archived there following the call for 90 days. Please connect to Sarepta’s website several minutes prior to the start of the broadcast to ensure adequate time for any software download that may be necessary.

On February 22, 2022 Poseida Therapeutics, Inc. (NASDAQ: PSTX), a clinical-stage biopharmaceutical company utilizing proprietary gene engineering platform technologies to create cell and gene therapeutics with the capacity to cure, reported that Brent Warner has joined the Company as President, Gene Therapy effective February 21, 2022 (Press release, Poseida Therapeutics, FEB 22, 2022, View Source [SID1234608823]).

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"Brent brings deep pharmaceutical expertise and a strong track record of leadership in gene therapy and rare genetic diseases to Poseida, and I am excited to welcome him to our team," said Mark Gergen, Chief Executive Officer of Poseida. "Alongside our top scientists, he will lead the execution of drug development programs in gene therapy, including our recent research collaboration with Takeda. It’s an exciting time at Poseida, and I look forward to working with Brent as we continue to advance our innovative gene therapy programs."

Mr. Warner has more than 15 years of biotech and pharmaceutical experience, most recently serving as Vice President, Gene Therapy and Rare Disease at Novartis, where he was responsible for building a division to commercialize multiple gene therapies overseeing three therapeutic areas. Prior roles included serving as a U.S. commercial leader in Hemophilia A at BioMarin Pharmaceutical Inc. and a variety of strategic operational roles at Biogen. Before that, he held commercial launch roles in blood disorders at Baxalta, then a biopharmaceutical division spun off by Baxter International and now a wholly owned subsidiary of Takeda. Warner has an MBA with an emphasis in marketing and finance and a Bachelor of Business Administration degree, both from Northwood University in Midland, Mich.

"I am thrilled to join Poseida, which has built an unparalleled platform to deliver novel cell and gene therapies for patients with high unmet need," Warner said. "Together with Poseida’s outstanding team, I look forward to the opportunity to accelerate potential single-treatment cures for the rare disease community."

On February 22, 2022 Neoleukin Therapeutics, Inc., "Neoleukin" (NASDAQ:NLTX), a biopharmaceutical company utilizing sophisticated computational methods to design de novo protein therapeutics, reported , reported it will report full year 2021 financial results on Tuesday, March 1, 2022 after the close of financial markets and then host a conference call and live audio webcast to discuss these results and provide a corporate update (Press release, Neoleukin Therapeutics, FEB 22, 2022, View Source [SID1234608822]). Details of the event are as follows:

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The archived audio webcast will be available on the Investor Relations section of the Neoleukin website approximately two hours after the event and will be available for replay for at least 30 days after the event.

On February 22, 2022 Kiniksa Pharmaceuticals, Ltd. (Nasdaq: KNSA) (Kiniksa), a biopharmaceutical company with a portfolio of assets designed to modulate immunological pathways across a spectrum of diseases, and Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd., a wholly-owned subsidiary of Huadong Medicine Co., Ltd. (Huadong Medicine), reported a strategic collaboration to develop and commercialize Kiniksa’s ARCALYST and mavrilimumab in the Asia Pacific Region (Press release, Kiniksa Pharmaceuticals, FEB 22, 2022, View Source [SID1234608820]).

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"This collaboration aims to bring Kiniksa’s therapeutics to patients in the Asia Pacific Region suffering from severe autoimmune and inflammatory diseases. With extensive regional experience, proven development and regulatory execution, and deep relationships with a broad network of hospitals and clinics, Huadong Medicine is an ideal partner to help drive value," said Sanj K. Patel, Chairman and Chief Executive Officer of Kiniksa. "The collaboration also provides non-dilutive capital, cost-sharing, and resources for clinical trials to accelerate our drug development and commercialization efforts."

"Kiniksa is an emerging leader in the development of immune-modulating therapies, for which there is significant unmet need across the Asia Pacific Region," said Liang Lv, Chairman and CEO of Huadong Medicine. "In addition to ARCALYST, the first and only FDA-approved treatment for recurrent pericarditis, the compelling clinical data generated to-date for mavrilimumab provide foundational support for development across a range of underserved diseases. We look forward to working closely with Kiniksa to leverage our clinical, regulatory, and commercial capabilities in the Asia Pacific Region."

Under the terms of the collaboration, Kiniksa will receive $22 million upfront and is eligible to receive up to approximately $640 million in specified development, regulatory and sales-based milestones. Kiniksa is also eligible to receive tiered royalties ranging from the low-teens to the low-twenties on annual net sales. Huadong Medicine will obtain exclusive rights and responsibility for the development and commercialization of ARCALYST and mavrilimumab in the Asia Pacific Region including Greater China, South Korea, Australia, and 18 other countries, but excluding Japan. Kiniksa will otherwise retain all existing development and commercialization rights for both assets.