26/10/2021: Theradiag launches a Rights Issue

On October 26, 2021 THERADIAG (ISIN: FR0004197747, Ticker: ALTER), a company specializing in in vitro diagnostics and Theranostics, reported the launch of a rights issue for a target amount of €5,334,745,24, at a price of €1.22 per share with a nominal discount of 30.05% to the closing price on 21 October 2021, and a ratio of 1 new share for every 2 existing shares (the "Rights Issue") (Press release, Theradiag, OCT 26, 2021, View Source [SID1234591930]).

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Bertrand de Castelnau, CEO of Theradiag, said: "Our strategic refocus on innovation and the commercial development of our two activities, Theranostics and in vitro diagnostics, has enabled us to post very solid growth in recent semesters and be close to breakeven in the first half of 2021[1]. On the basis of buoyant activity for our innovative solutions and a healthier cost structure, we are entering a new phase of profitable growth with the aim of strengthening our global leadership on the biotherapy monitoring market.

Theradiag stands out on this growing biotherapy monitoring market through its expertise and its ties with the healthcare professionals ecosystem in France and abroad. Building on these assets, the Company wants to begin a new chapter in its history through this fundraising operation that will enable it to finance the five projects that will structure its future growth:

Secure the quality and commercial supply of antibodies via the Humabdiag project developed thanks to the recent partnership with the University of Tours (bioproduction of human monoclonal antibodies);
Accelerate the internationalization of existing activities in the world’s main healthcare countries, and in particular accelerate sales in the United States (which already account for 19% of Theranostics revenue);
Develop a technological solution to ensure Near Patient Testing;
Invest in new therapeutic fields with a substantial medical need and strong growth (e.g. oncology, central nervous system, rheumatology, etc.);
Thanks to the expertise acquired in autoimmune diseases, reposition and revive FIDIS technology, in particular in the United States, and the activity covering serums used in quality control.
Through our current structure and these five routes of development that present substantial synergies, our unique positioning will provide a response to the substantial demand on the rapidly growing global biotherapy monitoring market.

In this perspective, the planned use of the funds raised in the capital increase will be as follows:

50% of the funds will be used to strengthen the sales team by recruiting sales professionals in the United States, France and the rest of the world, to develop the autoimmunity portfolio and to design a marketing campaign for Theradiag products;
30% of the funds to research new therapeutic areas, develop new products and adapt near-patient testing;
10% of the funds raised to accelerate product registrations in several countries, particularly the United States, in order to increase international sales; and
Up to 10% of the funds raised, in order to finance Theradiag’s working capital requirements, open subsidiaries and improve production facilities.
If the issue is limited to 75%, the funds will be used as follows:

50% of the funds will be used to strengthen the sales team by recruiting sales professionals in the United States, France and the rest of the world, to develop the autoimmunity portfolio and to design a marketing campaign for Theradiag’s products;
30% of the funds to research new therapeutic areas, develop new products and adapt near-patient testing;
10% of the funds raised to accelerate product registrations in several countries, particularly the United States, in order to increase international sales; and
10% of the funds raised to finance Theradiag’s working capital requirements, open subsidiaries and improve production facilities.
Theradiag is thus preparing for a new growth phase that requires the financial means to match its ambitions. We want to involve you in this new phase by launching a Rights Issue of approximately 5.3 million euros (through the issuance of up to 4,372,742 shares at a price of €1.22 each). The funds raised will be allocated to boost our R&D and internationalize our activities in our key geographic areas, which are France and the United States. Our goal is to achieve annual revenue of over €40 million[2] within five years while keeping our costs strictly under control in order to achieve an operating margin of between 20 and 30%. This ambition should be achieved through organic growth and the implementation of the five development axes described. With the exception of public grants and subsidies, the Company does not expect to call on other complementary financing".

Pierre Morgon, Chairman of the Board, adds: "We are determined to take Theradiag to a new dimension thanks to the added value of our solutions and the current dynamic of the market segments we are targeting. On behalf of the Board of Directors and our entire team, I would like to thank you for your trust in and support for this operation that should put Theradiag on a track to faster growth and contribute to strengthening its leadership position in biotherapy monitoring".

[1] The Company’s operating result and net result at 30 June 2021 amount to -178 K€ and -92 K€ respectively.

[2] The Company’s sales as at 30 June 2021 was €5.5 million.

EpiAxis to present at STEM 2021 Conference

On October 26, 2021 EpiAxis Therapeutics reported that it is among 25 emerging companies that will be showcased at Wholesale Investor’s STEM 2021 Conference on Thursday, October 28 (Press release, EpiAxis Therapeutics, OCT 26, 2021, View Source;utm_medium=rss&utm_campaign=epiaxis-to-present-at-stem-2021-conference [SID1234591924]).

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Breakthroughs in Science, Technology, Engineering, and Mathematics (STEM) have formed the foundation for critical disruptions across many industries and sectors in the last decade. STEM is the realm where our most significant problems are discovered, and the mechanism whereby these problems can be solved.

EpiAxis recently joined Wholesale Investor, Australasia’s leading investment platform that connects innovative, emerging companies that are looking to raise capital with an active, engaged and growing ecosystem of more than 29,300 high-net-worth investors, fund managers, family offices, PE and VC firms, government bodies and industry participants.

CEO Jeremy Chrisp will present at the Virtual Investor Showcase to raise awareness and visibility for EpiAxis’ epigenetic pipeline of therapies, which work differently to existing – and often toxic – cancer treatments by uniquely reprograming (re-train) the cancer cells back towards normal cells. Chrisp will discuss how our epigenetic science aims to maintain and extend cancer remission, with low side effects.

The showcase includes everything investors need to capitalise on STEM investment opportunities:

25 emerging companies solving problems in the space of; Renewable Energy, Life Sciences, AgriTech, FinTech, Data, and AI
Panel sessions from globally leading STEM investors discussing their due diligence process and sectors of interest
Live Q&A/interaction with panellists
Ability to conduct one-on-one meetings with founders of ventures

Delcath Systems Schedules Conference Call to Report 2021 Third Quarter Financial Results

On October 25, 2021 Delcath Systems, Inc. (Nasdaq: DCTH), an interventional oncology company focused on the treatment of rare primary and metastatic cancers of the liver, reported it will host a conference call on Nov 9, 2021 at 8:30 AM Eastern Time to discuss results for its third quarter ended September 30, 2021 (Press release, Delcath Systems, OCT 25, 2021, View Source [SID1234595188]).

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Conference Call Information

To participate in this event, dial approximately 5 to 10 minutes before the beginning of the call.

The call will also be available over the Internet and accessible at:

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Israel’s Silenseed Raises $7.8 Million for China RNAi Joint Venture

On October 25, 2021 Silenseed, a Tel Aviv RNAi company, reported that it raised $7.8 million from the Guangzhou Sino-Israel Bio-Industry Investment Fund to start a China JV (Press release, Silenseed, OCT 25, 2021, View Source [SID1234593957]). Silenseed-China will own the rights to develop, market and sell Silenseed’s RNAi products in China. The Israeli company will use the capital to conduct a Phase III trial of its lead candidate, which targets the KRAS oncogene to treat pancreatic cancer. Silenseed’s novel drug delivery platform enables the insertion of RNAi therapeutics directly into solid tumors. GIBF will own a 49% stake in the Silenseed Chinese subsidiary.

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Entry into a Material Definitive Agreement

On October 25, 2021, Oncotelic Therapeutics, Inc. (the "Company") reported that it entered into an Unsecured Convertible Note Purchase Agreement (the "Purchase Agreement") with Golden Mountain Partners, LLC (the ("Holder"), pursuant to which the Company issued a convertible promissory note in the aggregate principal amount of $0.5 million (the "Note"), which Note is convertible into shares of the Company’s common stock, par value $0.01 per share ("Common Stock") (Filing, 8-K, Mateon Therapeutics, OCT 25, 2021, View Source [SID1234592110]).

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The Note carries an interest rate of 2% per annum and matures on the earlier of (a) the one-year anniversary of the date of the Agreement, or (b) the acceleration of the maturity of the Note by Holder upon occurrence of an Event of Default (as defined below). The Note contains a voluntary conversion mechanism whereby the Holder may convert the outstanding principal and accrued interest under the terms of the Note into shares of Common Stock (the "Conversion Shares"), at the consolidated closing bid price of the Company’s Common Stock on the applicable OTC Market as of the date the Company receives a Notice of Conversion (as defined in the Note) from Holder. Prepayment of the Note may be made at any time by payment of the outstanding principal amount plus accrued and unpaid interest. The Note contains customary events of default (each an "Event of Default"). If an Event of Default occurs, at the Holder’s election, the outstanding principal amount of the Note, plus accrued but unpaid interest, will become immediately due and payable in cash. The Purchase Agreement requires the Company to use of the proceeds received under the Note to support the clinical development of OT-101, including payroll and has been made in continuation of the relationship between the Company and the Holder.

The issuance of the Note is exempt from the registration requirements of the Securities Act of 1933, as amended ("Securities Act"), in reliance on the exemptions provided by Section 4(a)(2) of the Securities Act as provided in Rule 506 of Regulation D promulgated thereunder. The shares of Common Stock issuable upon conversion of the Note have not been registered under the Securities Act or any other applicable securities laws, and unless so registered, may not be offered or sold in the United States except pursuant to an exemption from the registration requirements of the Securities Act.

The foregoing descriptions of the Purchase Agreement and the Note are qualified in their entirety by reference to the full text of such agreements, copies of which are attached hereto as Exhibit 10.1 and 10.2, respectively, and each of which is incorporated herein in its entirety by reference.