VYANT BIO REPORTS THIRD QUARTER 2021 RESULTS AND PROVIDES STRATEGIC BUSINESS UPDATES

On November 11, 2021 Vyant Bio, Inc. ("Vyant Bio", "Company") (Nasdaq: VYNT), an emerging global drug discovery company, reported that is rapidly identifying small and large molecule therapeutics to treat central nervous system (CNS) and oncology-related diseases (Press release, Vyant Bio, NOV 11, 2021, View Source [SID1234595434]). With leading-edge capabilities in data science, biological and chemical sciences, engineering, and regulatory affairs, Vyant Bio capitalizes on in silico, human cell-derived in vitro disease models, and in vivo discovery technologies to identify novel biological targets and valuable therapeutics for patients. Today, Vyant Bio reports its Third Quarter 2021 strategic and business updates in a conference call scheduled for 4.30pm ET.

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"We are pleased with the progress our R&D team is making to further our CNS rare disease and oncology related HER2+ drug discovery programs," stated Jay Roberts, CEO of Vyant Bio. The timing of Dr. Robert Fremeau’s arrival as our Chief Scientific Officer coincides well with our acceleration to later-stage drug discovery. Dr. Fremeau’s extensive experience with scientific research and drug discovery will be invaluable to us as we complete feasibility programs with leading biopharma companies, and develop our preclinical and translational strategy for driving a portfolio of therapeutic candidates from early discovery to human proof-of-concept".

"Vyant Bio is committed to transforming the way drugs are discovered by quickly adapting to exciting new technologies and combining our internal capabilities in ways that leverage the strength of our scientific and data science teams along with innovative technologies," stated Robert Fremeau, CSO of Vyant Bio. "Our internal teams of scientists, data scientists, and engineers, coupled with the capabilities of select strategic partners that are now integrated into our platform, allow us all to work together to design and develop superior therapeutics and position us to build a robust pipeline of novel therapeutics targeting degenerative and developmental neurological disorders and cancers with high unmet needs."

The Company expects to file its quarterly report for the Third Quarter 2021 on Form 10-Q tomorrow with the Securities and Exchange Commission. Please refer to Vyant Bio’s Form 10-Q for more detailed information with respect to our financial results for the three and nine months ended September 30, 2021.

THIRD QUARTER 2021 FINANCIAL RESULTS1

As StemoniX, Inc. was deemed to have acquired Cancer Genetics, Inc. for accounting purposes and the Merger closed on March 30, 2021, the Company’s Third Quarter 2021 financial results include the post-merger results of the combined companies, now known as Vyant Bio. The analysis below excludes the Third Quarter 2020 results as they are based solely on StemoniX’s historical stand-alone operations and therefore do not reflect the post-merger enterprise.

Cash and cash equivalents totaled $23.2 million as of September 30, 2021.

Total revenues were $1.5 million for the three months ended September 30, 2021. Cost of goods sold – service aggregated to $1.1 million for the three months ended September 30, 2021 resulting in a cost of goods sold of 80% of service revenues. Cost of goods sold – product aggregated to $159 thousand for the three months ended September 30, 2021 resulting in a cost of goods sold gross margin deficit of $196 thousand. Our product manufacturing capabilities currently have excess capacity to support future growth. Research and development expenses were $1.2 million for the three months ended September 30, 2021. Selling, general and administrative expenses were $3.3 million for the three months ended September 30, 2021.

While the Company executes its drug development strategy for long-term growth, the Company currently generates revenue from its vivoPharm and StemoniX subsidiaries. On a pro forma basis, assuming the Merger occurred on January 1, 2020, revenues for the three and nine-month ended September 30, 2021 were $1.5 million and $5.3 million, respectively, as compared with $1.9 million and $5.0 million for the respective prior-year periods. On a pro forma basis, revenues (decreased) increased by (21)% and 5% in the current-year three and nine-month periods as compared with the same prior-year periods.

1Pro forma information gives effect to the Merger between Cancer Genetics, Inc. and StemoniX, Inc. as if the Merger had occurred as of January 1, 2020. The pro forma information is presented solely for informational purposes and is not necessarily indicative of the combined results of operations or financial position that might have been achieved for the periods or dates indicated, nor is it necessarily indicative of the future results of the Company.

Vyant Bio’s Conference Call and Webcast and Information

Vyant Bio’s management will host a conference call on Thursday, November 11, 2021 at 4:30 pm ET to discuss the Third Quarter 2021 results and provide strategic business updates as well as answer questions. Event information is below:

The live event will be recorded and available for replay. The conference call and webcast details are also included inside the Investors section of the Vyant Bio corporate website at www.vyantbio.com.

Immutep Announces Publication of AIPAC, TACTI-002 and TACTI-003 Abstracts
for SITC 2021 Annual Meeting & AIPAC Global Webcast Details

On November 11, 2021 Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep" or "the Company"), a biotechnology company developing novel LAG-3 related immunotherapy treatments for cancer and autoimmune disease, reported that data from its AIPAC, TACTI-002 and TACTI-003 studies have been published in abstracts available via the links below on the SITC (Free SITC Whitepaper) 2021 Annual Meeting’s official website or the Company’s website (Press release, Immutep, NOV 11, 2021, View Source [SID1234595396]).

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Three poster presentations with additional data and commentary that are not included in the abstracts will be available on View Source from 12 November 2021, at 7 am EST and made available on Immutep’s website at www.immutep.com.

TACTI-002
Title: Results from a Phase II study of eftilagimod alpha (soluble LAG-3 protein) and pembrolizumab in patients with PD-L1 unselected metastatic 2nd line head and neck squamous cell carcinoma (HNSCC).
Abstract: View Source
TACTI-003
Title: A Phase II study of eftilagimod alpha (soluble LAG-3 protein) and pembrolizumab in patients unselected for PD-L1 expression in first line metastatic head and neck squamous cell carcinoma (HNSCC).
Abstract: View Source
AIPAC
Note: A separate announcement detailing the AIPAC results has also been released today.
Immutep Limited, Level 12, 95 Pitt Street, Sydney NSW 2000

ABN: 90 009 237 889

Title: Final results from AIPAC: A phase IIb comparing eftilagimod alpha (a soluble LAG-3 protein) vs. placebo in combination with weekly paclitaxel in HR+ HER2- MBC.
Abstract: View Source
Webcast Details
Immutep will present the AIPAC data in a global webcast for investors. Details are as follows:
Date & Time 8.00 am AEDT (Sydney) Wednesday 17 November 2021
4.00 pm EST (New York) Tuesday 16 November 2021
10.00 pm CET (Berlin) Tuesday 16 November 2021
Register: View Source
Questions: Investors are invited to submit questions in advance via [email protected].

Silverback Therapeutics to Participate in the Stifel 2021 Virtual Healthcare Conference

On November 11, 2021 Silverback Therapeutics, Inc. (Nasdaq: SBTX) ("Silverback"), a clinical-stage biopharmaceutical company leveraging its proprietary ImmunoTAC technology platform to develop systemically delivered, tissue targeted therapeutics for the treatment of cancer, chronic viral infections, and other serious diseases, reported that the Company will participate in the Stifel 2021 Virtual Healthcare Conference from November 15-17, 2021 (Press release, Silverback Therapeutics, NOV 11, 2021, View Source [SID1234595345]).

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Laura Shawver, Ph.D., Silverback’s Chief Executive Officer, and Valerie Odegard, Ph.D., Silverback’s President and Chief Scientific Officer, will participate in a fireside chat on Wednesday, November 17, 2021 at 2:40 PM ET (11:40 AM PT). The live webcast of the event will be available on Silverback’s investor relations website and a replay will be available for 30 days following the event. Members of the Silverback management team will also host investor meetings during the conference.

ORIC Pharmaceuticals to Participate in Upcoming Investor Conferences

On November 11, 2021 ORIC Pharmaceuticals, Inc. (Nasdaq: ORIC), a clinical stage oncology company focused on developing treatments that address mechanisms of therapeutic resistance, reported that management will participate in the following investor conferences (Press release, ORIC Pharmaceuticals, NOV 11, 2021, View Source [SID1234595343]):

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Jefferies London Health Conference – Participating in a virtual fireside chat on Thursday, November 18, 2021, at 8:00 a.m. GMT.

Evercore ISI 4th Annual HealthconX Conference – Participating in a virtual fireside chat on Thursday, December 2, 2021, at 3:55 p.m. ET.
Webcasts of the fireside chats will be available through the investor section of the company’s website at www.oricpharma.com. Replays of the webcasts will be available for 90 days following the events.

Emergent BioSolutions Announces Stock Repurchase Program

On November 11, 2021 Emergent BioSolutions Inc. (NYSE: EBS) reported that its Board of Directors has authorized management to repurchase up to $250 million of the company’s common stock from time to time on the open market or in privately negotiated transactions (Press release, Emergent BioSolutions, NOV 11, 2021, View Source [SID1234595335]). This repurchase authorization expires on November 11, 2022.

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"As part of a balanced capital management plan, we believe the company’s stock can represent an attractive investment opportunity," said Robert G. Kramer, president and chief executive officer at Emergent BioSolutions. "This announcement demonstrates our confidence in Emergent’s business and the strength of our balance sheet and cash position, providing the flexibility to implement this program while simultaneously pursuing opportunities to invest and grow the business both organically and through potential acquisitions."

The timing and amount of any shares repurchased will be determined by the company’s management based on its evaluation of market conditions and other factors, consistent with its insider trading policy. Repurchases may also be made under a pre-established trading plan under Rule 10b5-1 that might result in shares being repurchased when the company might otherwise be precluded from doing so. The repurchase program may be suspended or discontinued at any time. Any repurchased shares will be held in treasury shares and will be available for use in connection with the company’s stock plans and for other corporate purposes.

The repurchase program will be funded using the company’s cash on hand and cash from operations. As of September 30, 2021, the company had cash and cash equivalents of $403.8 million.

The company had approximately 53.7 million shares of common stock outstanding as of September 30, 2021.