Asieris to Present World’s Innovative Photodynamic Products at 19th IPA Congress

On June 6, 2025 Asieris reported that the 19th International Photodynamic Association (IPA) Congress will convene in Shanghai from June 10-16, 2025 (Press release, Asieris Pharmaceuticals, JUN 6, 2025, View Source [SID1234653766]). Asieris Pharmaceuticals (Stock Code: 688176.SH) will participate under the theme "Illuminating Tomorrow, Healing with Light" showcasing two globally innovative photodynamic therapy (PDT).

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Among them, APL-1702—the world’s first and only non-invasive drug-device combination for cervical precancerous lesions—has demonstrated confirmed efficacy through an international multicenter Phase III clinical study. It is poised to provide a fertility-friendly, non-invasive solution for cervical cancer prevention systems in China and globally.

Concurrently, Asieris will exhibit APL-1706, its drug for bladder cancer diagnosis or surgical procedures. APL-1706 is currently the only approved optical imaging agent for assisting bladder cancer diagnosis or surgical procedures worldwide. The combined use of APL-1706 and blue light cystoscopy (BLC) for managing non-muscle invasive bladder cancer (NMIBC) is included in international and domestic guidelines/expert consensus.

The IPA is the preeminent global academic organization in photodynamic therapy, hosting its prestigious biennial congress—often hailed as the "Olympics of PDT." Centered on the theme "Integrating Photodynamic Basic Research and Clinical Applications for Human Health," IPA 2025 will gather leading scholars, clinical experts, and industry leaders to explore cutting-edge advancements and the vast potential of PDT.

A pioneer in photodynamic therapy for gynecological precancerous lesions, Prof. Peter Hillemanns will deliver an invited lecture on "Efficacy of APL-1702 in Patients with Cervical High-Grade Squamous Intraepithelial Lesions (HSIL): A Subgroup Analysis of the APRICITY1 Study." He serves as Director of the Department of Gynecology and Obstetrics at Hannover Medical School, Director of the Claudia von Schilling Cancer Center (CCC Hannover), and Spokesperson for the Comprehensive Cancer Center Lower Saxony, applying his specialization in gynecology and oncology.

Additionally, in the Gynecology Session (Part 1), the session chair Prof. Fei Chen from Peking Union Medical College Hospital, Chinese Academy of Medical Sciences will present APL-1702 study data.

Additionally, Prof. Lihua Qiu (Renji Hospital, Shanghai Jiao Tong University School of Medicine) and other prominent experts will lead keynote speeches on the latest clinical applications of PDT for cervical intraepithelial lesions.

[HIGHLIGHTED ACADEMIC AGENDA]

June 12, 08:45–09:05
Session: Featured Presentation

Speaker: Prof. Peter Hillemanns

Topic: Efficacy of APL-1702 in patients with cervical HSIL: A subgroup analysis of the APRICITY study

June 12, 10:15–12:15
Session: Oral Presentation

Session Chair: Prof. Peter Hillemanns & Prof. Fei Chen

Topic: Gynecology Session 1

June 14, 13:45–15:45
Session: Oral Presentation

Session Chair: Prof. Lihua Qiu

Topic: Gynecology Session 2

IPA 2025 is not only a premier academic event but also a vital platform for advancing the industrialization of photodynamic therapy. Asieris anticipates that deep dialogues with global experts will accelerate APL-1702’s international expansion, contributing Chinese expertise and solutions to the global strategy of "Accelerating the Elimination of Cervical Cancer."

Join us to witness the highlights of this landmark event!

Venue: Shanghai International Convention Center (2727 Binjiang Avenue, Pudong, Shanghai)

Asieris Booth: A02,3rd Floor

Phio Pharmaceuticals Announces Strategic Initiative to Create Awareness of the Comprehensive INTASYL siRNA Portfolio

On June 6, 2025 Phio Pharmaceuticals Corp. (NASDAQ: PHIO) a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL gene silencing technology to treat cancer, reported a strategic initiative to heighten awareness of potential applications of the broader INTASYL siRNA portfolio, which includes approximately 30 compounds (Press release, Phio Pharmaceuticals, JUN 6, 2025, View Source [SID1234653765]). Recently, positive interim safety and efficacy results were reported in the on-going Phase 1b dose escalation clinical trial with the INTASYL compound PH-762 for the treatment of skin cancer. Clinical and preclinical data to date suggest promise for other potential applications across the INTASYL portfolio.

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Mr. Robert Infarinato has been appointed to the role of VP, Strategic Development, effective June 9, 2025. He will be transitioning from his role as Chief Financial Officer to concentrate on directing strategic business development initiatives focusing on potential applications of the broader INTASYL portfolio. Concurrently, Ms. Lisa Carson, was appointed VP, Finance and Administration and will lead Phio’s finance team.

Mr. Infarinato has over 30 years of finance and accounting leadership experience. He served as head of a consulting firm, advising on operational matters including funding and IPO process. Previous positions include serving as Chairman of the Board of Trustees for Abington Health and as executive Vice President and CFO of an international service company.

Ms. Carson joined Phio in May 2025 with more than 20 years of finance and accounting leadership experience. She most recently was VP, Finance and Controller at Prelude Therapeutics, where she supported the company’s IPO and expansion. Ms. Carson also held leadership roles at TELA Bio and PhaseBio Pharmaceuticals.

"It is a great pleasure to announce the new positions of these two experienced professionals," said Robert Bitterman, Phio’s CEO and President. "This strategic move underscores the company’s commitment to gain greater awareness of the potential applications in our INTASYL siRNA portfolio."

UroGen Pharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

On June 6, 2025 UroGen Pharma Ltd. (Nasdaq: URGN), a biotech company dedicated to developing and commercializing innovative solutions that treat urothelial and specialty cancers, reported the grants of inducement restricted stock units ("RSUs") to 27 new employees in connection with their employment with UroGen (Press release, UroGen Pharma, JUN 6, 2025, View Source [SID1234653764]). These new team members will support the ongoing commercialization of Jelmyto (mitomycin) for pyelocalyceal solution, UroGen’s first approved product, and the continued development of the Company’s pipeline.

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Up to 118,000 ordinary shares of UroGen are issuable upon the vesting and settlement of the RSUs. The RSUs will vest equally over three years, with one-third of the underlying shares vesting each year on the anniversary of the vesting date, subject in each case to the employee’s continued service relationship with UroGen.

The RSUs are subject to the terms and conditions of UroGen’s 2019 Inducement Plan and RSU grant notice and agreement thereunder. The RSUs were granted as an inducement material to each employee entering into employment with UroGen in accordance with Nasdaq Listing Rule 5635(c)(4).

TG Therapeutics to Participate in the Goldman Sachs 46th Annual Global Healthcare Conference

On June 6, 2025 TG Therapeutics, Inc. (NASDAQ: TGTX) reported that Michael S. Weiss, the Company’s Chairman and Chief Executive Officer, will participate in the Goldman Sachs 46th Annual Global Healthcare Conference, being held in Miami, FL on June 9-11, 2025 (Press release, TG Therapeutics, JUN 6, 2025, View Source [SID1234653763]). The fireside chat is scheduled to take place on Tuesday, June 10, 2025, at 10:40am ET.

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A live webcast of the fireside chat will be available on the Events page, located within the Investors & Media section, of the Company’s website at View Source

Replimune Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

On June 6, 2025 Replimune Group, Inc. (NASDAQ: REPL), a clinical stage biotechnology company pioneering the development of novel oncolytic immunotherapies, reported the grant of inducement equity awards to newly hired non-executive employees (Press release, Replimune, JUN 6, 2025, View Source [SID1234653762]).

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The Company granted equity awards to 10 employees as a material inducement to commencing their employment with the Company under the Company’s 2025 Inducement Grant Incentive Compensation Plan (the "Inducement Plan"). The inducement awards consist of non-qualified stock options to purchase an aggregate of 36,485 shares of the Company’s common stock and restricted stock units representing an aggregate of 41,080 shares of the Company’s common stock. Each option has an exercise price of $9.75 per share, which is equal to the closing price of the Company’s common stock on June 5, 2025 (the "Date of Grant"). Each option has a 10-year term and will vest over four years, with 25% of the underlying shares vesting on the one-year anniversary of the Date of Grant, and the remainder vesting in monthly installments for three years thereafter. The restricted stock units vest in approximately four equal annual installments beginning on May 15, 2026.

The aforementioned inducement awards were approved by the compensation committee of the Company’s board of directors in reliance on the employment inducement exception under Nasdaq Listing Rule 5635(c)(4). The inducement awards are subject to the terms and conditions set forth under the Inducement Plan.