On August 3, 2021 Personalis, Inc. (Nasdaq: PSNL), a leader in advanced genomics for cancer, reported that its management team will participate at the 6th Annual Needham Virtual MedTech & Diagnostics 1×1 Conference on Tuesday, August 17, 2021 (Press release, Personalis, AUG 3, 2021, View Source;1-Conference [SID1234585646]).

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On August 3, 2021 Epizyme, (Nasdaq: EPZM), a fully integrated, commercial-stage biopharmaceutical company developing and delivering novel epigenetic therapies, reported that management will host a conference call to discuss its second quarter 2021 financial results and provide a business update on Monday, August 9, 2021 at 8:30 a.m. ET (Press release, Epizyme, AUG 3, 2021, View Source [SID1234585645]).

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To participate in the conference call, please dial (877) 844-6886 (domestic) or (970) 315-0315 (international) and refer to conference ID 3658407. A live webcast will be available in the investor section of the company’s website at www.epizyme.com, and will be archived for 60 days following the call.

On August 3, 2021 BostonGene Corporation, a biomedical software company committed to defining optimal precision medicine-based therapies for cancer patients, reported a publication in Blood Cancer Journal, a peer-reviewed journal that focuses on hematologic malignancies and related disorders (Press release, BostonGene, AUG 3, 2021, View Source [SID1234585644]). The manuscript "Lack of intrafollicular memory CD4+ T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma" underscores the role of intrafollicular CD4 expression to independently predict treatment outcomes of high-risk follicular lymphoma (FL) patients.

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"We’re proud to support Mayo Clinic in its mission to predict treatment outcomes for patients with newly diagnosed follicular lymphoma"

Early event-free status (EFS) at 12 and 24 months are good indicators of subsequent prolonged survival and lengthy life expectancy in FL. However, an unmet need remains to predict early EFS at diagnosis to better treat patients with optimal therapeutics. This discovery and validation study evaluated the tumor microenvironment (TME) determinants of early failure in patients with newly diagnosed FL and integrated the results into the Follicular Lymphoma International Prognostic Index (FLIPI), the clinically-driven scoring system of survival in FL. This research study analyzed the prevalence of T-cell subsets and macrophages in the pretreatment biopsy specimens of newly diagnosed patients with FL who were prospectively enrolled in the Molecular Epidemiology Resource (MER) cohort at Mayo Clinic and the University of Iowa. To support this work, BostonGene conducted comprehensive analysis of Co-Detection by Indexing (CODEX) multiplex immunofluorescence data generated by the Villasboas Lab at Mayo Clinic to characterize intratumoral immunophenotypes. The study revealed that insufficient intrafollicular CD4 expression was the main predictor of early failure, leading to the development of a novel bio-clinical risk model (called BioFLIPI), where lack of CD4 intrafollicular expression moved patients up one FLIPI risk group, ultimately improving the identification of patients at risk for early failure at diagnosis.

"Leveraging BostonGene’s analytical capacity to explore the ultrahigh plex CODEX imaging datasets generated in our laboratory furthered our understanding of the composition and spatial distribution of immune cells within the TME," said J. C. Villasboas, MD at Mayo Clinic. "These key insights are critical to improving clinical outcomes for FL patients."

This work is the result of the research collaboration between Mayo Clinic and BostonGene to uncover key tumor characteristics that can be exploited to develop personalized therapies for lymphoma patients.

"We’re proud to support Mayo Clinic in its mission to predict treatment outcomes for patients with newly diagnosed follicular lymphoma," said Nathan Fowler, MD, Chief Medical Officer at BostonGene. "With our combined transformational technologies, we have a significant opportunity to identify patients with the highest risk of early failure and personalize treatment."

On August 3, 2021 NantHealth, Inc. (NASDAQ: NH), a provider of enterprise solutions that help businesses transform complex data into actionable insights, reported the appointment of Tiffany Avery, MD, MPH, as Chief Medical Officer (Press release, NantHealth, AUG 3, 2021, View Source [SID1234585643]). In her new position, Dr. Avery will be responsible for providing clinical strategic direction and guiding the development and deployment of NantHealth’s Eviti decision support platform and other innovative products and services.

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"Appointing Dr. Avery to our leadership team is an incredibly valuable addition to the organization, particularly as we expand into areas like population health and additional disease states for Eviti," said Ron Louks, Chief Operating Officer, NantHealth. "With her background in medical oncology, epidemiology, and cancer and health disparities, Dr. Avery will play a key role in helping NantHealth to deliver valuable, equitable care and improved outcomes to the patients and populations we serve."

Dr. Avery joined NantHealth in January of 2019 as Medical Director of Oncology. Prior to her role at NantHealth, she served as an Assistant Professor of Oncology at Thomas Jefferson University and Wake Forest Baptist Health. After completing fellowship training at The University of Texas MD Anderson Cancer Center in Houston, Texas, Dr. Avery focused and lectured on clinical research and the care of breast cancer patients. In the community, Dr. Avery is a recognized expert and invited speaker on topics including cancer prevention, treatments, clinical trials, and survival disparities. Over the course of her career, Dr. Avery has produced peer-reviewed publications, conference abstracts, editorials, and served as an investigator on numerous breast cancer clinical trials.

"I’m excited to be a part of NantHealth to reach our collective goal of improving health outcomes and providing value-based, quality healthcare," said Dr. Avery. "As an advocate for equitable care, in cancer but certainly in all of healthcare, not only does it make financial sense to all stakeholders, but it’s absolutely the right thing to do. Our technology helps deliver on that mission, and I’m honored to help guide us on this journey."

Dr. Avery earned her BS and MPH in Epidemiology from Tulane University, and MD from LSU Health Sciences Center New Orleans. She completed fellowship training in Hematology and Medical Oncology at MD Anderson Cancer Center. Dr. Avery recently earned certification in Lifestyle Medicine and is a co-host of 3 Black Docs, a podcast aimed at addressing health and cancer disparities.

On August 3, 2021 Omeros Corporation (NASDAQ: OMER), reported that the company will issue its second quarter financial results for the period ended June 30, 2021, on Monday, August 9, 2021, after the market closes (Press release, Omeros, AUG 3, 2021, View Source [SID1234585642]). Omeros management will host a conference call and webcast that day at 4:30 p.m. Eastern Time (1:30 p.m. Pacific Time) to discuss the financial results as well as recent developments and highlights.

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Conference Call Details

To access the live conference call via phone, please dial (844) 831-4029 from the United States and Canada or (920) 663-6278 internationally. The participant passcode is 4195376. Please dial in approximately 10 minutes prior to the start of the call. A telephone replay will be available for one week following the call and may be accessed by dialing (855) 859-2056 from the United States and Canada or (404) 537-3406 internationally. The replay passcode is 4195376.

To access the live and subsequently archived webcast of the conference call, go to Omeros’ website at View Source