Amgen To Present At The 2021 Evercore ISI Healthcare Conference

On November 24, 2021 Amgen (NASDAQ:AMGN) reported that it will present at the 2021 Evercore ISI Healthcare Conference at 5:10 p.m. ET on Tuesday, Nov. 30, 2021 (Press release, Amgen, NOV 24, 2021, View Source [SID1234596025]). Rob Lenz, M.D., Ph.D., senior vice president of Global Development at Amgen will present at the conference. Live audio of the conference call will be broadcast over the internet simultaneously and will be available to members of the news media, investors and the general public.

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The webcast, as with other selected presentations regarding developments in Amgen’s business given at certain investor and medical conferences, can be accessed on Amgen’s website, www.amgen.com, under Investors. Information regarding presentation times, webcast availability and webcast links are noted on Amgen’s Investor Relations Events Calendar. The webcast will be archived and available for replay for at least 90 days after the event.

Regulus Therapeutics Announces Private Placement of Equity

On November 24, 2021 Regulus Therapeutics Inc. (Nasdaq: RGLS), a biopharmaceutical company focused on the discovery and development of innovative medicines targeting microRNAs (the "Company" or "Regulus"), reported that it has entered into a definitive securities purchase agreement in connection with a private placement to certain institutional investors and other accredited investors (Press release, Regulus, NOV 24, 2021, View Source [SID1234596024]). The financing was led by the Federated Hermes Kaufmann Funds and New Enterprise Associates (NEA), with participation from other new and existing investors. Upon the closing of the financing, which is anticipated to occur on or about November 30, 2021, the Company expects to receive gross proceeds of approximately $34.6 million. The closing of the financing is subject to customary closing conditions.

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SVB Leerink is acting as the lead placement agent for the financing. H.C. Wainwright & Co. is acting as a co-placement agent for the financing.

Under the securities purchase agreement, the investors have agreed to purchase approximately 58.9 million shares of the Company’s common stock ("Common Stock") at a purchase price of $0.36 per share. Certain investors have also agreed to purchase, in lieu of shares of Common Stock, an aggregate of approximately 3,725,720 shares of newly designated, non-voting Class A-4 convertible preferred stock at a purchase price of $3.60 per share. Each share of non-voting Class A–4 convertible preferred stock will be convertible into 10 shares of Common Stock, subject to certain beneficial ownership conversion limitations.

The offer and sale of the foregoing securities are being made in a transaction not involving a public offering and have not been registered under the Securities Act of 1933, as amended (the "Securities Act"), or applicable state securities laws. Accordingly, the securities may not be reoffered or resold in the United States except pursuant to an effective registration statement or an applicable exemption from the registration requirements of the Securities Act and such applicable state securities laws.

This press release does not constitute an offer to sell or the solicitation of an offer to buy the securities, nor shall there be any sale of the securities in any state in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of such state.

Alkermes to Take Part in the Fourth Annual Evercore ISI HealthCONx Conference

On November 24, 2021 Alkermes plc (Nasdaq: ALKS) reported that management will participate in a fireside chat at the fourth annual Evercore ISI HealthCONx Conference on Thursday, Dec. 2, 2021 at 10:30 a.m. ET (3:30 p.m. GMT) (Press release, Alkermes, NOV 24, 2021, https://investor.alkermes.com/news-releases/news-release-details/alkermes-take-part-fourth-annual-evercore-isi-healthconx [SID1234596023]). The presentation may be accessed under the Investors tab on www.alkermes.com and will be archived for 14 days.

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Amgen To Present At The 2021 Piper Sandler Healthcare Conference

On November 24, 2021 Amgen (NASDAQ:AMGN) reported that it will present at the 2021 Piper Sandler Healthcare Conference at 1:00 p.m. ET on Wednesday, Dec. 1, 2021 (Press release, Amgen, NOV 24, 2021, View Source [SID1234596022]). Murdo Gordon, executive vice president of Global Commercial Operations and Peter H. Griffith, executive vice president and chief financial officer at Amgen will present at the conference . Live audio of the conference call will be broadcast over the internet simultaneously and will be available to members of the news media, investors and the general public.

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The webcast, as with other selected presentations regarding developments in Amgen’s business given at certain investor and medical conferences, can be accessed on Amgen’s website, www.amgen.com, under Investors. Information regarding presentation times, webcast availability and webcast links are noted on Amgen’s Investor Relations Events Calendar. The webcast will be archived and available for replay for at least 90 days after the event.

Philogen announces new collaboration with Janssen to discover small molecule therapeutics

On November 24, 2021 Philogen S.p.A., a clinical-stage biotechnology company focused on antibody and small molecule-based targeted therapeutics, reported that its wholly-owned Swiss subsidiary, Philochem AG, has entered into a new collaboration and option agreement with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, to discover new small molecules of pharmaceutical interest utilizing Philochem’s novel lead-generation technologies (Press release, Philogen, NOV 24, 2021, View Source [SID1234596021]). The agreement was facilitated by Johnson & Johnson Innovation.

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Under the terms of the agreement, Philochem will work with Janssen to apply its proprietary DNA-encoded chemical library technology platform, seeking to identify small molecule compounds that bind to specific targets. Janssen may exercise the options to use these identified ligands as candidates for further drug discovery and development activities.

Prof. Dario Neri, co-founder and Chief Executive Officer of Philogen commented: "We are pleased to establish another collaboration with Janssen and we hope our technology will contribute to providing innovative treatments for serious unmet medical needs."

Philogen’s main focus is on the discovery and development of targeted anti-cancer therapeutics, which selectively accumulate at the site of disease helping spare normal tissue. Besides the successful development of antibody-cytokine fusions, Philogen has used its encoded library platform to identify small organic ligands with ultra-high affinity for tumor-associated antigens. These ligands are used for the selective delivery of diagnostic and therapeutic payloads including radionuclides or cytotoxic drugs to the site of disease. This approach is complementary to the use of antibody-cytokine fusions and the small molecule product candidates developed by Philogen have already obtained clinical proof-of-principle validation.

No financial details of the agreement were disclosed.