Jazz Pharmaceuticals Announces Participation in the Leerink 10th Annual Global Healthcare Conference

On February 17, 2021 Jazz Pharmaceuticals plc (Nasdaq: JAZZ) reported that the company will webcast its corporate presentation at the Leerink 10th Annual Global Healthcare Conference (Press release, Jazz Pharmaceuticals, FEB 17, 2021, View Source [SID1234575221]).

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Bruce Cozadd, chairman and chief executive officer, will provide an overview of the company and a business and financial update on Wednesday, February 24, 2021 at 1:40 p.m. EST / 6:40 p.m. GMT.

A live audio webcast of the presentation may be accessed from the Investors section of the Jazz Pharmaceuticals website at www.jazzpharmaceuticals.com. Please connect to the website prior to the start of the presentation to ensure adequate time for any software downloads that may be necessary to listen to the webcast.

An archive of the webcast will be available following the presentation for at least one week on the Investors section of the company’s website at www.jazzpharmaceuticals.com.

Avidity Biosciences to Present at the 10th Annual SVB Leerink Global Healthcare Conference

On February 17, 2021 Avidity Biosciences, Inc. (Nasdaq: RNA), a biopharmaceutical company pioneering a new class of oligonucleotide-based therapies called Antibody Oligonucleotide Conjugates (AOCs), reported that Sarah Boyce, President and Chief Executive Officer, and Art Levin, Ph.D., Chief Scientific Officer, will participate in a fireside chat at the 10th Annual SVB Leerink Global Healthcare Conference on Wednesday, February 24th, 2021 at 2:00pm PST (Press release, Avidity Biosciences, FEB 17, 2021, View Source [SID1234575220]). The conference is being held in a virtual format.

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A live webcast of the virtual fireside chat will be available on the Company’s website at www.aviditybiosciences.com in the Investors section. A replay of the fireside chat will be archived on the site for 90 days.

ESSA Pharma Announces Pricing of Public Offering of Common Shares

On February 17, 2021 ESSA Pharma Inc. ("ESSA", or the "Company") (Nasdaq: EPIX), a clinical-stage pharmaceutical company focused on developing novel therapies for the treatment of prostate cancer, reported the pricing of an underwritten public offering of 4,830,918 common shares at a public offering price of $27.00 per share, before underwriting discounts, for an aggregate offering of approximately $130.4 million (the "Offering") (Press release, ESSA, FEB 17, 2021, View Source [SID1234575219]). ESSA has granted the underwriters a 30-day option to purchase, in whole or in part, up to an additional 724,637 shares of its common shares (the "Option"). The proceeds to ESSA from the Offering are expected to be approximately $121.6 million after deducting underwriting discounts and commissions and other estimated offering expenses but excluding any exercise of the Option. ESSA intends to use the net proceeds of the Offering for pre-clinical and clinical activities, chemistry, manufacturing and controls, research and development, as well as working capital and general corporate purposes. All common shares to be sold in the Offering will be offered by ESSA.

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Jefferies and Piper Sandler are acting as joint book-running managers for the Offering. Oppenheimer & Co. is acting as lead manager for the Offering and Bloom Burton Securities Inc. is acting as co-manager for the Offering.

The securities described above are being offered by ESSA in the United States pursuant to a shelf registration statement on Form S-3 (File No. 333-250971) that was previously filed by ESSA with the Securities and Exchange Commission (the "SEC") and became effective on December 29, 2020 and in Canada pursuant to ESSA’s Canadian short form base shelf prospectus (the "Canadian Base Shelf Prospectus") dated August 24, 2020 that was previously filed with the securities regulatory authorities in each of the provinces of British Columbia, Alberta and Ontario.

A preliminary prospectus supplement related to the Offering was filed with the SEC on February 16, 2021 and is available on the SEC’s website at View Source and a final prospectus supplement related to the Offering will be filed with the SEC and will be available on the SEC’s website at View Source. A preliminary prospectus supplement to ESSA’s Canadian Base Shelf Prospectus was also filed with the securities regulatory authorities in each of the provinces of British Columbia, Alberta and Ontario on February 16, 2021 and is available at View Source and a final prospectus related to the Offering will be filed with the securities regulatory authorities in each of the provinces of British Columbia, Alberta and Ontario and will be available at View Source. Copies of the final prospectus supplements related to the Offering and the accompanying prospectuses can be obtained by contacting Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor, New York, NY 10022, by e-mail at [email protected] or by telephone at (877) 547-6340; or Piper Sandler & Co., Attention: Prospectus Department, 800 Nicollet Mall, J12S03, Minneapolis, MN 55402, or by telephone at 800-747-3924 or by email at [email protected].

The Company has applied to list the common shares sold under the Offering on the Nasdaq Capital Market. The Offering is expected to close on or about February 22, 2021, subject to customary closing conditions.

This press release does not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

Guardant Health to Participate in Upcoming Investor Conferences

On February 17, 2021 Guardant Health, Inc. (Nasdaq: GH), a leading precision oncology company, reported the company will be participating in the following virtual investor conferences (Press release, Guardant Health, FEB 17, 2021, View Source [SID1234575215]).

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10th Annual SVB Leerink Global Healthcare Conference
Fireside Chat on Friday, February 26th at 1:20 p.m. Pacific Time / 4:20 p.m. Eastern Time
Cowen 41st Annual Health Care Conference
Fireside Chat on Tuesday, March 2nd at 8:10 a.m. Pacific Time / 11:10 a.m. Eastern Time
Interested parties may access a live and archived webcast of the virtual sessions on the "Investors" section of the company website at: www.guardanthealth.com.

Natera and Personalis Partner for Personalized Monitoring in Oncology

On February 17, 2021 Personalis, Inc. (Nasdaq: PSNL), a leader in advanced genomics for cancer, and Natera, Inc. (Nasdaq: NTRA), a global leader in cell-free DNA testing, reported that the two companies have entered into a partnership in the field of personalized oncology (Press release, Personalis, FEB 17, 2021, View Source [SID1234575214]). The partnership will pair Personalis’ NeXT tumor profiling and diagnostic products with Natera’s personalized ctDNA platform Signatera for treatment monitoring and molecular residual disease (MRD) assessment.

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Under this non-exclusive agreement, Natera will validate the design of Signatera personalized ctDNA assays using matched tumor and normal exome sequence data from Personalis, and Natera will be responsible for commercialization. The agreement covers MRD testing for both clinical use and research use.

"This represents another step forward in Natera’s vision for Signatera, as a personalized monitoring and MRD platform that can be scaled and integrated robustly with high-quality exome-scale tissue sequencing assays worldwide, of which Personalis’ NeXT is a leading example," commented Solomon Moshkevich, Natera’s General Manager of Oncology. "We are pleased to partner with them and to expand access of Signatera to a new set of potential customers."

"The NeXT Platform complements Signatera by offering advanced tumor analysis with augmented coverage across all 20,000 genes," said Richard Chen, Chief Scientific Officer of Personalis. "We are excited to partner with Natera on this sensitive tumor-informed approach to accelerate molecular residual disease detection in cancer."