Phase 1/2 Clinical Trial Progress for IDE196 to be Presented at Society for Melanoma Research Congress

On November 15, 2019 IDEAYA Biosciences, Inc. (Nasdaq:IDYA), an oncology-focused precision medicine company committed to the discovery and development of targeted therapeutics to treat cancer, reported that it will present data from an ongoing Phase 1/2 clinical trial entitled "A Phase 1/2 Study in Patients with Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions" (ClinicalTrials.gov Identifier: NCT03947385) (Press release, Ideaya Biosciences, NOV 15, 2019, View Source [SID1234551385]). This clinical trial is evaluating the tolerability and preliminary clinical activity of IDE196 for the treatment of MUM and other solid tumors harboring GNAQ or GNA11 (GNAQ/11) mutations activating the PKC signaling pathway.

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An update on the Phase 1 Dose-Escalation portion of the ongoing Phase 1/2 clinical trial will be provided, including:

Dosing schema for dose escalation cohorts
Patient enrollment by dose cohort
Patient baseline characteristics
Summary of adverse events
Duration of treatment through data cut-off (October 28, 2019)
Data will be presented at the 16th International Congress for the Society for Melanoma Research (SMR Congress) at the Grand America Hotel in Salt Lake City, Utah, November 20-23, 2019.

Dr. Matteo Carlino, Medical Oncologist, Westmead Hospital and University of Australia, Westmead, Australia, will provide a poster presentation at the SMR Congress on November 20, 2019, entitled: "A phase 1/2 study of IDE196 in patients with metastatic uveal melanoma or solid tumors harboring GNAQ/11 mutations or PRKC fusions."

Dr. Meredith McKean, MD, MPH, Investigator, Melanoma Research Program at Sarah Cannon Research Institute, Nashville, TN, will provide an oral presentation, at a related meeting hosted by the Melanoma Research Foundation’s CURE Ocular Melanoma (OM) initiative in conjunction with the SMR Congress, on November 20, 2019.