On April 19, 2022 ProMIS Neurosciences, Inc. (TSX: PMN) (OTCQB: ARFXF), a biotechnology company focused on the discovery and development of antibody therapeutics targeting misfolded proteins such as toxic oligomers implicated in the development of neurodegenerative diseases, reported that it has appointed Larry Altstiel M.D. Ph.D., as Chief Medical Officer (Press release, ProMIS Neurosciences, APR 19, 2022, View Source [SID1234612501]).
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"Larry Altstiel has been a respected leader for over twenty years in the Alzheimer’s clinical research community, and we are delighted to welcome him to the ProMIS team", stated Gene Williams, ProMIS Chairman and CEO. "His deep knowledge of clinical research, regulatory pathways, and the neurodegenerative disease community will be a tremendous asset to ProMIS as we develop our portfolio of differentiated product candidates."
"ProMIS has shown compelling scientific rationale for the differentiation of PMN310 in Alzheimer’s disease" according to Dr. Altstiel. "ProMIS has developed unique and valuable methods for identification of misfolded proteins and toxic oligomeric forms of these proteins that may contribute to the development of a number of neurodegenerative diseases. In particular this approach supports the likely differentiation of PMN310 from other antibody approaches targeting other forms of Abeta. ProMIS’ unique technology platform has also led to the generation of potentially differentiated therapies in ALS and other neurodegenerative diseases. I look forward to helping advance this exciting portfolio in the clinic."
Larry Altstiel, M.D., Ph.D. brings decades of medical expertise in neurodegenerative diseases and experience in the pharmaceutical industry. At Pfizer, as vice president and head of neuroscience clinical research, Larry led the selection of drug candidates, development and oversight of multiple preclinical studies and clinical studies from Phase 1 through Phase 3. He is currently part time Chief Medical Officer at Pinteon Therapeutics. He received his Ph.D. in cell biology, virology, and physical chemistry from The Rockefeller University, completed a postdoctoral fellowship in cell biology at Harvard University and received an M.D. from the University of Miami Leonard M. Miller School of Medicine. He also completed a residency in Neurology at the Neurological Institute of New York, Columbia University College of Physicians and Surgeons.