On November 16, 2020 Q BioMed Inc. (OTCQB: QBIO), reported that it has received a patent from the U.S. Patent and Trademark Office for its Uttrocide-B molecule (Press release, Q BioMed, NOV 16, 2020, View Source [SID1234571182]). The Patent is titled "Uttroside-B and Derivatives Thereof as Therapeutics for Hepatocellular Carcinoma". Q BioMed has the exclusive rights to the technology through an agreement with the Rajiv Gandhi Centre for Biotechnology, an Autonomous Institute under the Department of Biotechnology, Government of India and the Oklahoma Medical Research Foundation. The Method Of Use patent covers the use of a novel pharmaceutical for the treatment of hepatocellular carcinoma. International and additional U.S. claims are currently under prosecution for the technology which addresses a severe unmet need for a safe and effective drug to treat hepatocellular carcinoma (HCC), the most common form of liver cancer.
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"This patent allowance in the U.S. comes at an opportune time as we are scaling up manufacturing and preparing Uttroside-B for an investigational new drug (IND) application with the U.S. FDA. Upon the FDA’s clearance, we anticipate initiating proof of concept studies by the end of next year," stated Q BioMed CEO Denis Corin.
Uttroside-B has shown ten times the potency against HCC as compared to the current standard of care drug in early pre-clinical investigation. Currently, there are only two approved first-line therapies for HCC. Challenges with current treatments include patients becoming resistant to the specific drugs, adverse side effects, and high costs. An estimated 700,000 people are diagnosed with HCC each year, with the global market for liver cancer drugs expected to grow to $3.9 billion by 2027.