On June 27, 2018 Sarah Cannon Research Institute – UK, Part of HCA Healthcare UK, reported the European initiation of a Phase II clinical trial studying the effectiveness of TIL therapy in the treatment of patients facing metastatic melanoma (Press release, Sarah Cannon Research Institute, JUN 27, 2018, View Source [SID1234527503]). Sarah Cannon is the first clinical site in Europe to treat a patient on this trial.
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Sarah Cannon Research Institute – UK, which provides access to clinical trials to both private and NHS cancer patients, is one of 25 centres around the world taking part in Iovance Biotherapeutics’ Phase II TIL trial. The patient population participating in the trial will include people with late-stage melanoma where prior treatments have proven ineffective. The initiation of this trial took place at HCA Healthcare UK at University College Hospital, a complex cancer facility in London.
"We are pleased to offer this cutting-edge immunotherapy option for patients facing melanoma throughout Europe," said Carol Woodward, Vice President of Sarah Cannon Development Innovations and European Operations. "Through Sarah Cannon Research Institute – UK, Part of HCA Healthcare UK, we can ensure patients have access to the latest treatments in their cancer journey."
TIL therapy is a procedure in which white blood cells that have left the bloodstream and migrated towards a tumour, TIL (tumour infiltrating lymphocytes), are enriched to help fight and reduce cancers. As part of the therapy, TIL cells are extracted from a patient’s tumour, amplified in a laboratory to increase their number, and then infused back into the patient. At the recent 2018 ASCO (Free ASCO Whitepaper) Annual Meeting, research for TIL therapy in abstract TPS9595, indicated the potential for durable and complete responses, even in heavily pre-treated patients.
"We are excited to offer this therapy to melanoma patients seeking the latest options," said Hendrik-Tobias Arkenau, MD, PhD, FRCP, Executive Medical Director of the Drug Development Program, Sarah Cannon Research Institute – UK. "TIL therapy is an innovative treatment that brings together a multidisciplinary team to provide patients with access to a complex and cutting-edge treatment approach."
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