On February 21, 2022 Silence Therapeutics plc, Nasdaq: SLN ("Silence" or "the Company"), a leader in the discovery, development and delivery of novel short interfering ribonucleic acid ("siRNA") therapeutics for the treatment of diseases with significant unmet medical need, reported that Craig Tooman, previously Chief Financial Officer ("CFO"), has been appointed President, Chief Executive Officer ("CEO") and Board member of Silence, and Mark Rothera has stepped down as President, CEO and Board member, effective immediately (Press release, Silence Therapeutics, FEB 21, 2022, View Source [SID1234608362]). Rhonda Hellums, previously Vice President, Finance, has been appointed CFO.

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"On behalf of the Board, I would like to thank Mark for his contributions over the last 18 months and we wish him well," said Iain Ross, Chairman at Silence. "Craig is a seasoned leader who understands all aspects of our corporate strategy and the immediate need to maximize our potential going forward. With Craig as CEO and Dr. Giles Campion leading our exceptional research and development efforts, I am confident that Silence is now well-positioned to capitalize appropriately on the positive data we recently reported with SLN360 and ensure long-term shareholder value."

Craig Tooman, President and CEO, commented, "I am extremely pleased to have the opportunity to lead Silence and have come to appreciate the strong stewardship of Iain Ross as Chairman of the Board. I look forward to working with Giles, the executive team, and full Board, to take Silence through its next exciting stage of growth."

Craig Tooman joined Silence in January 2021, and brings more than 30 years of operational, financial and merger and acquisition ("M&A") experience. Most recently, he was Chief Operating Officer and CFO at Vyome Therapeutics, and prior to this was CEO of Aratana Therapeutics where he successfully negotiated a merger with Elanco. Before Aratana, Mr. Tooman was the CEO of Avanzar Medical Inc., a private oncology company, and CFO of Enzon Pharmaceuticals until its acquisition by Sigma Tau. Prior to that he led the $1.1 billion M&A initiative and integration of ILEX Oncology and Genzyme Corporation. He also held key positions at Pharmacia and Upjohn. Mr. Tooman currently serves on the Supervisory Board and Audit Committee of CureVac, which accomplished a successful initial public offering on Nasdaq in August of 2020. He holds a BA in Economics from Kalamazoo College and an MBA from the University of Chicago.

Rhonda Hellums has over 25 years of corporate finance, accounting, strategic planning, M&A, treasury management, investor and public relations. Prior to joining Silence in April 2021, she held management positions at several large healthcare companies, including KCI (now 3M+KCI) and Genzyme Corporation. She previously served as CFO of Deer Oaks Mental Health and prior to that, CFO of Aratana Therapeutics, a publicly traded pet therapeutics company. Ms. Hellums received her BBA degree in Accounting and Information Systems and MBA from the University of Texas at San Antonio.