SkylineDx Confirms Positive Results First Independent Validation Skin Cancer Test

On September 30, 2019 SkylineDx reported, during the European Society for Medical Oncology congress (Barcelona, EU), that it successfully validated the performance of their skin cancer (melanoma) diagnostic test on the first, independent, European dataset (Press release, SkylineDx, SEP 30, 2019, View Source [SID1234539960]). This melanoma test combines genetic information from a patient’s tumor cells (taken during a diagnostic biopsy) with tumor – and patient specific characteristics. Based on this unique combination, the test is able to accurately predict the risk of having metastasis present in the lymph nodes without a patient having to undergo a surgery to remove (part of the) lymph nodes. The discovery came from an US patient population and remains robust in the Dutch validation population, saving 41% of patients an unnecessary surgical intervention [2].

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

These positive results follow last week’s announcement of launching a pilot study to evaluate and optimize the diagnostic services in clinical practice with a renowned US hospital in Q4 2019 and the start of a national trial in the US in 2020 [3]. "I am always anxious going into validation. If you optimize the performance of a test too much on the initial dataset, it will only work in that dataset and fails in an independent dataset," says Dharminder Chahal, CEO SkylineDx. "That we may present these positive results today during this major conference, is fantastic news for our team and gives everyone the needed energy and enthusiasm to continue the developments in our Falcon R&D Program to get this test from bench to bedside as quickly as possible."