On March 15, 2023 Targovax ASA (OSE: TRVX) reported that an abstract describing its circular RNA platform has been accepted for poster presentation at the 2023 American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting in Orlando, USA (Press release, Targovax, MAR 15, 2023, View Source [SID1234628800]).
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The abstract describes the advantage of protein expression utilizing Targovax´proprietary circAde vector system. By comparing protein expression from circRNA and mRNA-based vectors, it is shown that the circAde-system out-performs conventional mRNA-based designs, both in terms of protein expression level and durability. Persistent and prolonged protein expression in patients is expected to result in positive treatment outcomes. The results thus highlight the circAde platform’s potential for development of novel, more effective medicines for the treatment of cancer and other diseases.
The abstract has been released on the AACR (Free AACR Whitepaper) website (View Source!/10828/presentation/5271). The poster is scheduled for presentation Tuesday 18 April 2023 and will be available on Targovax’s website after the presentation.
Poster title: circAde: a circRNA-based system for prolonged and more effective treatment of cancer
Date and time: Tuesday 18 April 2023, 13:30- 17:00 CDT / 20:30-24:00 CET
Location: Orange County Convention Center, Orlando, Florida
Session title: High-throughput Screening, Lead Identification and Optimization, and in Silico Drug Discovery
Poster number: 5335 / 17
Presenter: Thomas Birkballe Hansen, VP Research, Targovax
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