On May 5, 2025, IGM Biosciences, Inc. (the "Company") reported to have received a notice of termination of that certain Collaboration and License Agreement (the "Agreement"), dated as of March 28, 2022, by and between the Company and Genzyme Corporation, a corporation organized under the laws of Massachusetts ("Sanofi"), pursuant to which Sanofi has elected to terminate the Agreement, at will, in its entirety (Filing, IGM Biosciences, MAY 5, 2025, View Source [SID1234652744]). The effective date of the termination is thirty (30) days after the date of such notice.

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Under the original terms of the Agreement, the Company had agreed to generate, develop, manufacture and commercialize IgM antibodies directed to six primary targets, three of which were oncology targets and three of which were immunology targets. The parties concluded that conducting further activities under the Agreement was not in the interests of either party.