On November 11, 2022 VBI Vaccines Inc. (Nasdaq: VBIV) (VBI), a biopharmaceutical company driven by immunology in the pursuit of powerful prevention and treatment of disease, reported that its abstract highlighting data from the ongoing Phase 2a study of VBI-1901, the Company’s cancer vaccine immunotherapeutic candidate in recurrent glioblastoma (GBM), was accepted for poster presentation at the 27th Annual Meeting and Education Day of the Society for Neuro-Oncology (SNO), taking place November 16-20, 2022 (Press release, VBI Vaccines, NOV 11, 2022, View Source [SID1234623833]).
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Presentation Details
Poster Number CTIM-14
Title: Comprehensive biomarker analysis of responders and non-responders in a Phase 2a trial of a CMV vaccine immunotherapeutic candidate (VBI-1901)
Session: Poster Session
Date: Friday, November 18, 2022
Poster Session Time: 7:30-9:30PM ET
Poster Presenter: Fabio M. Iwamoto, M.D., Deputy Director, Division of Neuro-Oncology and Assistant Professor of Neurology at the Columbia University Irving Medical Center
About VBI-1901 and GBM
VBI-1901 is a novel cancer vaccine immunotherapeutic candidate developed using VBI’s enveloped virus-like particle (eVLP) technology to target two highly immunogenic cytomegalovirus (CMV) antigens, gB and pp65. Scientific literature suggests CMV infection is prevalent in multiple solid tumors, including glioblastoma (GBM). GBM is among the most common and aggressive malignant primary brain tumors in humans. In the U.S. alone, 12,000 new cases are diagnosed each year. The current standard of care for treating GBM is surgical resection, followed by radiation and chemotherapy. Even with aggressive treatment, GBM progresses rapidly and has a high mortality.