On October 2, 2018 Arcus Biosciences, Inc. (NYSE:RCUS), a clinical-stage biopharmaceutical company focused on creating innovative cancer immunotherapies, reported that nine abstracts have been accepted for poster presentation at the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) Annual Meeting, which is being held from November 7-11, 2018 in Washington, D.C (Press release, Arcus Biosciences, OCT 2, 2018, View Source [SID1234529716]).

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Details of Arcus’s poster presentations are as follows.

AB928 (dual A2aR/A2bR antagonist)
Title: Development of biomarkers to assess adenosine generation & activity in support of clinical trials conducted with the adenosine receptor antagonist AB928
Poster Number: P35; Abstract ID: 10513
Poster Presentation Hours: Friday, Nov. 9, from 12:45 – 2:15 pm. and 6:30 – 8 pm ET
Poster Hall Location: Hall E

Title: Selection of optimized drug candidates, dosing regimen, pharmacodynamic endpoints, tumor types, and biomarkers for translating inhibition of the adenosine pathway into effective anti-tumor activity.
Poster Number: P668; Abstract ID: 10724
Poster Presentation Hours: Saturday, Nov. 10 from 12:20 – 1:50 pm and 7:00 – 8:30 pm ET
Poster Hall Location: Hall E

Title: A phase 1/1b study to evaluate the safety and tolerability of AB928, a novel dual adenosine receptor antagonist, in combination with chemotherapy in patients with breast or gynecologic malignancies
Poster Number: P320 (Trial in Progress); Abstract ID: 10688
Poster Presentation Hours: Saturday, Nov. 10 from 12:20 – 1:50 pm and 7:00 – 8:30 pm ET
Poster Hall Location: Hall E

Title: A phase 1/1b study to evaluate the safety and tolerability of AB928, a novel dual adenosine receptor antagonist, in combination with chemotherapy in patients with gastrointestinal malignancies
Poster Number: P321 (Trial in Progress); Abstract ID: 10700
Poster Presentation Hours: Friday, Nov. 9, from 12:45 – 2:15 pm. and 6:30 – 8 pm ET
Poster Hall Location: Hall E

Title: A phase 1/1b study to evaluate the safety and tolerability of AB928, a novel dual adenosine receptor antagonist, in combination with carboplatin/pemetrexed and pembrolizumab in lung cancer patients
Poster Number: P322 (Trial in Progress); Abstract ID: 10706
Poster Presentation Hours: Saturday, Nov. 10 from 12:20 – 1:50 pm and 7:00 – 8:30 pm ET
Poster Hall Location: Hall E

Title: A phase 1 study to evaluate the safety and tolerability of AB928, a novel dual adenosine receptor antagonist, with AB122, a programmed cell death-1 inhibitor, in patients with advanced malignancies
Poster Number: P323 (Trial in Progress); Abstract ID: 10711
Poster Presentation Hours: Friday, Nov. 9, from 12:45 – 2:15 pm. and 6:30 – 8 pm ET
Poster Hall Location: Hall E

AB122 (anti-PD-1 antibody)
Title: Preliminary results from an ongoing Phase 1 study of AB122, an anti-programmed cell death-1 (PD-1) monoclonal antibody, in patients with advanced solid tumors.
Poster Number: P673; Abstract ID: 10638
Poster Presentation Hours: Friday, Nov. 9, from 12:45 – 2:15 pm. and 6:30 – 8 pm ET
Poster Hall Location: Hall E

Title: Development of a robust, simplified method to measure receptor occupancy in peripheral blood from patients treated with a novel anti-PD1 agent, AB122.
Poster Number: P15; Abstract ID: 10495
Poster Presentation Hours: Friday, Nov. 9, from 12:45 – 2:15 pm. and 6:30 – 8 pm ET
Poster Hall Location: Hall E

AB154 (anti-TIGIT antibody)
Title: Preclinical characterization of AB154, a fully humanized anti-TIGIT antibody, for use in combination therapies
Poster Number: P697; Abstract ID: 10538
Poster Presentation Hours: Friday, Nov. 9, from 12:45 – 2:15 pm. and 6:30 – 8 pm ET
Poster Hall Location: Hall E