Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting

On April 21, 2026 Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle) technology, reported an oral presentation and multiple poster presentations across five abstracts at the American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper) 2026 Annual Meeting, taking place May 29–June 2 in Chicago.

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Presentation Details:

Title: Interim analysis results from Duravelo-2: Zelenectide pevedotin (zele; BT8009) + pembrolizumab in patients (pts) with previously untreated locally advanced/metastatic urothelial carcinoma (la/mUC)
Type: Rapid Oral Abstract Session
Session: Genitourinary Cancer – Kidney and Bladder
Date and Time: Monday, June 1, 8:30-8:36 a.m. CT
Abstract Number: 4516
Lead Author: Yohann Loriot, M.D., Institute Gustave Roussy

Title: Interim analysis results from Duravelo-2: zelenectide pevedotin (zele; BT8009) in patients (pts) with previously treated locally advanced/metastatic urothelial carcinoma (la/mUC)
Type: Poster Session
Session: Genitourinary Cancer – Kidney and Bladder
Date and Time: Sunday, May 31, 9 a.m.-12 p.m. CT
Abstract Number: 4566
Lead Author: Dan Petrylak, M.D., Yale School of Medicine

Title: Zelenectide pevedotin (BT8009) monotherapy in previously treated metastatic urothelial carcinoma (mUC): Update on Duravelo-1
Type: Poster Session
Session: Genitourinary Cancer – Kidney and Bladder
Date and Time: Sunday, May 31, 9 a.m.-12 p.m. CT
Abstract Number: 4563
Lead Author: Oscar Reig Torras, M.D., Hospital Clínic de Barcelona

Title: Zelenectide pevedotin (BT8009) plus pembrolizumab in 1L cisplatin-ineligible locally advanced/metastatic urothelial carcinoma: Update on Duravelo-1 B7
Type: Poster Session
Session: Genitourinary Cancer – Kidney and Bladder
Date and Time: Sunday, May 31, 9 a.m.-12 p.m. CT
Abstract Number: 4564
Lead Author: Ignacio Duran, M.D., Hospital Universitario Marqués de Valdecilla

Title: Identify optimized dosage for zelenectide pevedotin in locally advanced/metastatic urothelial carcinoma (la/mUC) using quantitative analyses
Type: Poster Session
Session: Genitourinary Cancer – Kidney and Bladder
Date and Time: Sunday, May 31, 9 a.m.-12 p.m. CT
Abstract Number: 4567
Lead Author: Yasong Lu, Ph.D., Bicycle Therapeutics

The presentations will be made available in the Publications section of the Bicycle Therapeutics website on the morning of each session.

(Press release, Bicycle Therapeutics, APR 21, 2026, View Source [SID1234664600])