On February 24, 2026 Bruker Spatial Biology, a division of Bruker Corporation (Nasdaq: BRKR) reported that it will expand its collaboration with Noetik Inc., following their prior study of more than 3500 patient samples with the CosMx Spatial Molecular Imager (SMI). CosMx SMI powers Noetik’s pre-training and scaling of bio-foundation models to perform complex genome-wide simulations of human cellular- and tissue-level biology to enable diverse therapeutics applications.
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"Noetik’s multiple spatial AI models, including the Oncology Counterfactual Therapeutics Oracle virtual cell, which can simulate patient biology and inform drug discovery, represent transformative breakthroughs for tackling human disease," said Dr. Mark R. Munch, President of the Bruker NANO Group. To develop self-supervised AI, Noetik leverages the CosMx SMI platform to generate the largest and most biologically complete single-cell and subcellular spatial transcriptomic and multiomic datasets in oncology.
Noetik is now further imaging thousands of additional patients with the CosMx whole transcriptome assay to train their world models that learn from human tissue data.
"Spatial context is necessary for training foundation models that truly learn human biology. We have demonstrated that our models exhibit clear scaling laws; as we ingest more high-resolution CosMx data, we see a predictable and powerful increase in the models’ ability to represent complex biology. We are excited to partner with Bruker to scale toward one billion spatially resolved human cells, spanning the breadth of oncology and beyond," said Ron Alfa, MD, PhD, Co-Founder and CEO of Noetik.
This collaboration builds on Bruker’s best-in-class spatial biology portfolio, including CosMx SMI, AtoMx SIP, CellScape XR, GeoMx DSP and PaintScape platform, which together support high fidelity data generation for discovery and translational research.
(Press release, Noetik AI, FEB 24, 2026, View Source [SID1234662954])