On July 17, 2026 Incyte (Nasdaq:INCY) reported that it will highlight data from several programs in its oncology portfolio in six presentations at the European Society of Medical Oncology (ESMO) (Free ESMO Whitepaper) Congress 2026, being held October 23 – 27, 2026, in Madrid.

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"The data at ESMO (Free ESMO Whitepaper) will further illustrate Incyte’s commitment to advancing innovation for patients with cancer," said Pablo J. Cagnoni, M.D., President, Incyte and Global Head of Research and Development. "Among the presentations are important updates from our KRAS G12D inhibitor in advanced pancreatic cancer and colorectal cancer, our TGFβR2×PD-1 bispecific antibody in microsatellite stable colorectal cancer and our CDK2 inhibitor in recurrent epithelial ovarian cancer – investigational approaches that reflect our focus on areas where there is significant need for novel therapies."

Details on key data presentations at ESMO (Free ESMO Whitepaper) include:

Rapid Oral Presentations

INCB161734 (KRAS G12D)

Safety and Efficacy of Oral KRAS G12D Inhibitor INCB161734 as Monotherapy or in Combination with Cetuximab (Cetux) in Patients (pts) with Advanced/Metastatic Colorectal Cancer (CRC)
(Session: Rapid Oral session. Sunday, October 25, 3:30-5:00 a.m. ET [8:30-10:00 a.m. CET]. Abstract #1007RO.)

Safety and Efficacy of INCB161734, a Novel Oral KRAS G12D Inhibitor, in Combination with Chemotherapy in Patients (pts) with Advanced/Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
(Session: Rapid Oral session. Monday, October 26, 9:45-11:15 a.m. ET [2:45-4:15 p.m. CET]. Abstract #3137RO.)

INCA33890 (TGFβR2xPD-1)1

INCA33890, a TGFβR2xPD-1 Bispecific Antibody, with Standard of Care (SoC) Anticancer Therapies for Microsatellite Stable Colorectal Cancer (MSS CRC)
(Session: Rapid Oral session. Saturday, October 24, 2:30-4:00 a.m. ET [8:30-10:00 a.m. CET]. Abstract #1954RO.)

INCB123667 (CDK2)

Preliminary Efficacy of INCB123667 (CDK2 Inhibition) with Bevacizumab in Recurrent Epithelial Ovarian Cancer (rEOC)
(Session: Rapid Oral session. Friday, October 23, 10:15-11:45 a.m. ET [4:15-5:45 p.m. CET]. Abstract #1241RO.)

Poster Presentations

Retifanlimab

Final Survival Outcomes (OS) in POD1UM-303/InterAACT-2: a Phase 3 Study of Retifanlimab (R) + Carboplatin-Paclitaxel (CP) in First-Line (1L) Advanced Squamous Anal Cancer (SCAC)
(Session: Rectal and anal cancer. Sunday, October 25, 7:00-7:45 a.m. ET [12:00-12:45 p.m. CET]. Abstract #3536P.)

INCB123667 (CDK2)

A Phase 3, Double-Blind, Randomized, Controlled Study of INCB123667 with Bevacizumab Versus Bevacizumab Alone as First-Line Maintenance Therapy for Advanced Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Overexpressing Cyclin E1 (MAESTRA 3; GOG-3146; ENGOT-OV106)
(Session: Gynaecological cancers. Monday, October 26, 7:00-7:45 a.m. ET [12:00-12:45 p.m. CET]. Abstract #1336TiP.)

(Press release, Incyte, JUL 17, 2026, View Source [SID1234669296])